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《China Foreign Medical Treatment》 2010-31
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Analysis of Cellular Immunity in Children with Intestinal and Extraintestinal Rotavirus Infection

Objective To investigate the change of cellular and humoral immunity in children with rotavirus enteritis with extraintestinal manifestions.Methods The patients with rotavirus enteritis were enrolled between 2008.10and 2009.2for identification T lymphocyte subsets,serum Immunoglobulin A,Immunoglobulin G,Immunoglobulin M.Results The level of serum Immunoglobulin A,Immunoglobulin G,Immunoglobulin M in children with rotavirus enteritis and extraintestinal manifestions as were obviously decreased compared with the controls,and CD4+lymphocytes and the ratio of CD4+/CD8+ were increased compared with the controls.CD3+、CD8+lymphocytes were no obvious difference between the two groups.Conclusion Cellular and humoral immunity in children with rotavirus extraintestinal manifestions were obvious disturbance which might be relative to the extraintestinal spreading of rotavirus.
【CateGory Index】: R725.1
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