Comparison of Several Methods of Bronchoscopic Treatment of Lymph Nodes Fistula Type(Ⅵ) Tracheobronchial Tuberculosis(TBTB)
HU Zhimin;ZHAN Zhihua;WANG Fei;Department of Respiratory Diseases Intervention,Wuhan Medical Treatment Center;Clinical Laboratory, Wuhan Institute for Tuberculosis Control;
Objective To evaluate the effect of different combinations of bronchoscopic treatment of lymph nodes fistula type tracheobronchial tuberculosis(TBTB) by analyzing the clinical data so as to put forward the best treatment. Methods 38 cases of lymph nodes fistula type TBTB patients admitted in our hospital from June, 2009 to December, 2012 were divided into 3 groups according to the intervention method. Patients in A group were treated with local injection of anti-TB drugs and biopsy forceps debridement. Patients in B group were treated with local injection of anti-TB drugs and biopsy forceps debridement and cryoablation.Patients in C group were treated with local injection of anti-TB drugs and cryoablation. The efficacy and complications of different intervention combinations were evaluated, the data of the groups of patients adopted chi-square test of four-fold table. Results Of the 38 cases of patients, at the 12 months' treatment, 25 cases were cured, the cure rate was 65.8%(25/38), improved in 13 cases,the overall efficiency was 100%. The average bronchoscopic interventional times of A group were(20 ±4.0)times, and those of B group were(12±3.0) times, those of C group were 11±4.0 times, the difference between A group and C group was statistically significant(P0.05). the incidence of bleeding of A group, B group, C group was 77.0%, 84.0%, 60.0%, respectively, compared with A group and B group(P0.05). The cure rate of C group at the treatment of 2 months, 6 months and 12 months was much higher than that of A group and B group(P0.05). Conclusion Lymph nodes fistula type tracheobronchial tuberculosis(TBTB) using bronchoscopic local injection of anti-TB drugs and cryoablation therapy can reduce the number of interventional bronchoscopy with less bleeding complications.