Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Chinese Journal of Disease Control and Prevention》 2003-05
Add to Favorite Get Latest Update

The study of dose-response relationship of pulsed electromagnetic radiation on rat blood-brain-barrier

WANG Qi 1, REN Dong-qing 1, KUANG Fang 2, SUN Jing-min 2, WANG Jin 1, PANG Yi-bing 1, GUO Yao 1, GUO Guo-zheng 1. 1.Department of Radiation Medicine, Fourth Military Medical University, Xi'an 710032, China; 2.Institute of Neuroscience, Fourth Military Medical University, Xi'an 710032, China  
Objective To investigate the dose-response relationship of electromagnetic radiation on rat blood-brain-barrier (BBB). Methods Evans blue (EB) was used on the rat by intravenous injection, then observed the effect of pulsed electromagnetic radiation (EMR) in different pulses through fluorescent microscope. Results EB could form fluorescent faculae in brain where the BBB permeability had changed; the number and area of fluorescent faculae increased along with pulse numbers (0-200 pulses). Fluorescent faculae in EMR group were distributed over the rat brain, especially in cerebral cortex, thalamus, hypothalamus, cerebellum, caudate putamen and medulla oblongata. Conclusions Pulsed EMR in different frequence could induce different quantitative change of BBB permeability in rat brain, at 200 pulses the change was the most obvious, cerebral BBB permeability changed obvious more than others.
【Fund】: 全军“十五”指令性课题 (0 1L0 70 )
【CateGory Index】: Q691
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 8 Hits
1 XU Hui1, SHEN Xue-Feng1, LUO Wen-Jing1, HE Guang-Bin2, YANG Yan-Xia1, CHEN Jing-Yuan1, LIU Yi-Ping3, WANG Qiang11Department of Occupational and Environmental Health, School of Preventive Medicine, 2Department of Ultrasonographic Diagnostics, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China, 3Institute of Microbiology Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China;Pathological changes of rats' retina after exposure to pulsed electromagnetic radiation[J];Journal of The Fourth Military Medical University;2005-11
2 HOUWugang ZHAO Jie ZHANG Yuanqiang ZENG Lihua GUOGuozhen (Department of Histology and Embryology, Fourth Military Medical University, Xi 'an 710032) (Department of Radiation Medicine, Faculty of Preventive Medicine, Fourth Military Medical University, Xi'an 710032);Radiation effects of electromagnetic pulses on mouse blood-testis barrier[J];Journal of Radiation Research and Radiation Processing;2005-06
3 WANG Qi~(1),ZHANG Yuan-ju~(2),WANG Jin~(3),REN Dong-qing~(3),SONG Zu-jun~(1),GUO Guo-zhen~(3),GUO Yao~(3).1.Department of Emergency Xijing Hospital,Xi'an 710032;2.Department of Physiotherapy and Rehabilition.Fourth Military Medical University,Xi'an 710032,China;3.Department of Radiation Medicine,Fourth Militory Medical University,Xi'an 710032,China;Influence of electromagnetic radiation on ultrastructure and permeability of blood-brain barrier on rats[J];Chinese Journal of Disease Control & Prevention;2006-01
4 QIU Lian-bo, DING Gui-rong, TAN Juan, GUO Guo-zhen. Department of Radiation Medicine, Faculty of Preventive Medicine, the Fourth Military Medical University, Xi’an 710032, China;The role of actin in the electromagnetic pulse induced blood-brain barrier opening[J];Chinese Journal of Disease Control & Prevention;2010-06
5 ZHANG Cheng-Gang(State Key Laboratory of Proteomics,Beijing Institute of Radiation Medicine, Beijing100850,China);Contemplation on the military radiation medicine research[J];Bulletin of the Academy of Military Medical Sciences;2009-01
6 GAO Ya-bing,LI Xiang,WANG Shui-ming,WANG Li-feng,ZHAO Li,DONG Ji,YAO Bin-wei,PENG Rui-yun(Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China);Application of Evans blue dye to the detection of permeability of BBB after microwave radiation[J];Military Medical Sciences;2011-05
7 LI Xiang,HU Xiang-jun,PENG Rui-yun,et al.Institute of Radiation Medicine,Academy of Military Medical Science(Beijing 100850,China);Effects of microwave radiation on permeability changes of blood-brain barrier in rats[J];Chinese Journal of Public Health;2008-07
8 HU Yuan1,YUAN Mo2,LIU Ping1,MU Lihua1,WANG Hong1(1.Depertment of Clinical Pharmacology and Pharmacy,Chinese PLA General Hospital,Beijing 100853,China;2.General Hospital of Second Artiuery Corps,Beijing 100088,China);Effect of Acorus tatarinowii schott on ultrastructure and permeability of blood-brain barrier[J];China Journal of Chinese Materia Medica;2009-03
【Citations】
Chinese Journal Full-text Database 2 Hits
1 Kuang Fang; Wang Bairen; Wang Ling ;Yang Zhijun ;Duan Xiaoli; Ju Gong(Institute of Nerosciences, the Fourth Military Medical Uaiversity,Xi’an);APPLYING EVAN'S BLUE TO EXAMINE THE ADRENALINE-INDUCED OPENING OF THE BLOOD-BRAIN BARRIER WITH FLUORESCENCE MICROSCOPE[J];CHINESE JOURNAL OF NEUROANATOMY;1997-04
2 Ding Guirong, Xie Xuejun, Zhang Liyan,et al.Department of Radiation Medicine, Fourth Military Medical University, 710032;Changes of Nitric Oxide Synthase in Hippocampus and Cerebellum of the Rat Following Exposure to Electromagnetic Pulse[J];Chinese Journal of Physical Medicine;1998-02
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Xiao-Bin, WANG Xiang-Tao, LI Sha,HOU Xin-Pu △ (Department of Pharmaceutics,Peking University School of Pharmaceutical Sciences, Beijing 100083, China);Preparation of the liposomes containing Evens blue and its distribution in mice[J];Journal of Beijing Medical University;2002-04
2 TONG Jian guo, WANG Xian rong, ZHU Gang, FENG Hua (Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Chongqing 400038,China);Experimental study on the therapeutic effect and mechanism of Huoxuehuayu-Mixture in contusion and laceration of the brain[J];Acta Academiae Medicine Militaris Tertiae;2001-07
3 KUANG Fang, WANG Bai Ren, JU Gong Institute of Neuroscience of Chinese PLA, Fourth Military Medical University, Xi'an 710033, China;Effect of intravenous injection of lipoplysaccharide and small dose of adrenaline on the opening of blood brain barrier[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;2000-01
4 QU Run Jiang 1, GUO Yao 1, WANG Shu Fang 2, ZHENG Zhen Xing 1 1Department of Radiation Medicine, Faculty of Preventive Medicine,Xi'an 710033, China, 2Department of pathology, Tangdu Hospital, Xi'an 710038,China,Fourth Military Medical Unive;Effects of electromagnetic pulse on Fos protein in hypothalamic suprachiasmatic nucleus and pineal glands of rats[J];JOURNAL OF THE FOURTH MILITARY MEDICAL UNIVERSITY;2000-08
5 XU Hui1, SHEN Xue-Feng1, LUO Wen-Jing1, HE Guang-Bin2, YANG Yan-Xia1, CHEN Jing-Yuan1, LIU Yi-Ping3, WANG Qiang11Department of Occupational and Environmental Health, School of Preventive Medicine, 2Department of Ultrasonographic Diagnostics, Xijing Hospital, Fourth Military Medical University, Xi'an 710033, China, 3Institute of Microbiology Epidemiology, Academy of Military Medical Sciences, Beijing 100071, China;Pathological changes of rats' retina after exposure to pulsed electromagnetic radiation[J];Journal of The Fourth Military Medical University;2005-11
6 HOUWugang ZHAO Jie ZHANG Yuanqiang ZENG Lihua GUOGuozhen (Department of Histology and Embryology, Fourth Military Medical University, Xi 'an 710032) (Department of Radiation Medicine, Faculty of Preventive Medicine, Fourth Military Medical University, Xi'an 710032);Radiation effects of electromagnetic pulses on mouse blood-testis barrier[J];Journal of Radiation Research and Radiation Processing;2005-06
7 WANG Qi 1, GUO Yao 1, REN Dong qing 1, ZENG Li hua 1, KUANG Fang 2, SUN Jing min 2, WANG Jin 1, PANG Yi bing 1, GUO Guo zhen 1. 1.Department of Radiation Medicine, Fourth Military Medical University, Xi'an 710032, China; 2.Institute of Neuroscience, Fourth Military Medical University, Xi'an 710032, China;The influence of electromagnetic radiation in different intensity on rat's brain-blood-barrier[J];Chinese Journal of Disease Control and Prevention;2003-02
8 WANG Qi 1, GUO Guo zhen 1, ZENG Li hua 1, REN Dong qing 1, MA Fu cheng 2, WANG Jin 1, PANG Yi bing 1, GUO Yao 1. 1.Department of Radiation Medicine, Fouth Military Medical University, Xi'an 710032, China; 2.Department of Pathology, Faculty of Preclinical Medicine, The Fouth Military Medical University, Xi'an 710032, China;The influence of electromagnetic radiation at different time after irradiation on rat brain-blood-barrier[J];Chinese Journal of Disease Control and Prevention;2003-03
9 Ren Dongqing Zeng Guiying Zhang Shiying Department of Radiation Medicine,Faculty of Military Preventive Medicine,Fourth Military Medical University,Xi'an 710032,China;Experimental study on the structural damage of the blood-brain barrier induced by overpressure blast in rat[J];Medical Journal of Chinese People's Liberation Army;2007-08
10 SHEN Ya-wen,ZHAO Yan-yan,WANG Wen-an.Department of Neurology,Xinhua Hospital at Chongming,Shanghai Jiaotong University School of Medicine,Shanghai 202150,China;Effect of diabetes on expression of intercellular adhesion molecule-1 and injury of brain tissue and blood-brain barrier in cerebral ischemia rats[J];Journal of Clinical Neurology;2011-02
China Proceedings of conference Full-text Database 3 Hits
1 Wang Qi, GUO Yao, REN Dong-Qing, Zeng Li-Hua, KuangFang, GUO Guo-Zheng (Fourth Military Medical University: Department of Radiation medicine, Institute of Neuroscience, Xi' an 710032, China);The study of influence of Electromagnetic radiation in different intensity on rat Brain-blood-barrier[A];[C];2002
2 Wang Qi, REN Dong-Qing ,Kuang Fang,Sun Jing-Min,Wang Jin.Pang Yi-Bing. GUO Yao, GUO Guo-Zheng, (Fourth Military Medical University: Department of Radiation medicine, Institute of Neuroscience, Xi' an 710032, China);The study of Dose-effect relationship of Pulsed Electromagnetic radiation on rat Brain-blood-barrier[A];[C];2002
3 Wang Qi, GUO Guo-Zheng, Zeng Li-Hua, REN Dong-Qin g, Ma Fu-cheng Wang Jin. Pang Yi-Bing. GUO Yao (Fourth Military Medical University: Department of Radiation medicine, Department of Pathology, faculty of Preclinical Medicine. Xi' an 710033, China);The study of the influence of Electromagnetic radiation at different time after irradiation on rat Brain-blood-barrier[A];[C];2002
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Li Junyou;Yu Yan;Hao Jun;Jin Hua;Xu Huijun(304 Hospital of PLA,Beijing 100037);Determination of diamine oxdase activity in intestinal tissue and blood using spectrophotometry[J];AMINO ACIDS & BIOTIC RESOURCES;1996-04
2 WU Li-Wen,YIN Fei,PENG Jing,WANG Wei-Dong,GAN Na.Department of Pediatrics,Xiangya Hospital,Central South University,Changsha 410008,China;The tight junction proteins ZO-1,occludin and actin participate in the permeability increasing of blood-brain barrier induced by hypoxia-ischemia[J];Chinese Journal of Contemporary Pediatrics;2008-04
3 Bei Weihui Cao Yi(School of Radiation Medicine and Public Health,Suzhou University,Suzhou,215123);Biological Effects of Electromagnetic Radiation[J];Radiation Protection Bulletin;2007-03
4 GUO Dehuang; DONG Bo; WEN Gengyun; LUO Qingliang; MAO Bingzhi (Institute of Radiation Medicine, Academy of Military Medical Science, Beijing 100850);EFFECTS ON PROLIFERATION AND CELL CYCLE OF IRRADIATED KG-1 CELLS STIMULTATED BY CM-CSF[J];JOURNAL OF RADIATION RESEARCH AND RADIATION PROCESSING;2000-02
5 HOUWugang ZHAO Jie ZHANG Yuanqiang ZENG Lihua GUOGuozhen (Department of Histology and Embryology, Fourth Military Medical University, Xi 'an 710032) (Department of Radiation Medicine, Faculty of Preventive Medicine, Fourth Military Medical University, Xi'an 710032);Radiation effects of electromagnetic pulses on mouse blood-testis barrier[J];Journal of Radiation Research and Radiation Processing;2005-06
6 ;The Impact of the Joint Training in the Complex Electromagnetic Environment[J];National Defense Science & Technology;2008-04
7 CHEN Li-xin . Department of Ultrasonography, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China;Behaviors of contrast agents in the ultrasound field and emerging contrast imagings[J];;2004-03
8 Peng Yaoshu( Dept. of Acupuncture and Moxibustion, Guangzhou University of TCM, Guangzhou 510407);Experimental Study on the Model Selection and TCMP in theTreatment of the Animals with Epilepsy[J];HUNAN GUIDING JOURNAL OF TRADITIONAL CHINESE MEDICINE AND PHARMACOLOGY;1999-11
9 WANG Qi 1, GUO Yao 1, REN Dong qing 1, ZENG Li hua 1, KUANG Fang 2, SUN Jing min 2, WANG Jin 1, PANG Yi bing 1, GUO Guo zhen 1. 1.Department of Radiation Medicine, Fourth Military Medical University, Xi'an 710032, China; 2.Institute of Neuroscience, Fourth Military Medical University, Xi'an 710032, China;The influence of electromagnetic radiation in different intensity on rat's brain-blood-barrier[J];Chinese Journal of Disease Control and Prevention;2003-02
10 WANG Qi 1, GUO Guo zhen 1, ZENG Li hua 1, REN Dong qing 1, MA Fu cheng 2, WANG Jin 1, PANG Yi bing 1, GUO Yao 1. 1.Department of Radiation Medicine, Fouth Military Medical University, Xi'an 710032, China; 2.Department of Pathology, Faculty of Preclinical Medicine, The Fouth Military Medical University, Xi'an 710032, China;The influence of electromagnetic radiation at different time after irradiation on rat brain-blood-barrier[J];Chinese Journal of Disease Control and Prevention;2003-03
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 JI Xinxin HOU Wugang ZHAO Jie ZHAO Yong LI Wei ZHANG Yuanqiang (Department of Histology and Embryology, Fourth Military Medical University, Xi’an 710032);Expression and localization of Smad4, Smad1 and Smad5 in testis of mice exposed to electromagnetic pulses[J];Journal of Radiation Research and Radiation Processing;2006-06
2 JI Xinxin HOU Wugang ZHAO Jie ZHAO Yong LI Wei ZHANG Yuanqiang (Department of Histology and Embryology, Fourth Military Medical University, Xi’an 710032);The expression of Smad4 after radiation of electromagnetic pulses and apoptosis in spermatogenic cells in mouse[J];Journal of Radiation Research and Radiation Processing;2007-02
3 YANG Yang1 HOU Wugang2 ZENG Lihua3 ZHAO Jie2 LI Zhen2 ZHANG Yuanqiang21(Department of Dentistry and Clinical Medicine;Fourth Military Medical University,Xi’an 710032,China) 2(Department of Histology and Embryology,Fourth Military Medical University,Xi’an 710032,China) 3(Department of Radiation Medicine,Fourth Military Medical University,Xi’an 710032,China);The effects of electromagnetic pulses on the expression of TGF-βs in testis of mice[J];Journal of Radiation Research and Radiation Processing;2011-01
4 XU Kai1 HOU Wugang1 ZENG Lihua2 ZHAO Jie1 LI Zhen1 ZHANG Yuanqiang1 1(Department of Histology and Embryology,Fourth Military Medical University,Xi’an 710032,China) 2(Department of Radiation Medicine,Fourth Military Medical University,Xi’an 710032,China);Effect of electromagnetic pulses on the expression of occludin in testis of mice[J];Journal of Radiation Research and Radiation Processing;2011-05
5 WANG Yafeng;MIAO Xia;YANG Mingjuan;LANG Haiyang;JIANG Dapeng;ZHANG Jie;ZHAO Tao;ZENG Lihua;GUO Guozhen;Department of Radiation Medicine,The Fourth Military Medical University;State Key Laboratory of Electrical Insulation and Power Equipment,Xi'an Jiaotong University;Navy Health and Epidemic Prevention Team,Navy General Hospital;;Effects of electromagnetic pulse exposure on the development of reproduction system of male BALB/c mice[J];Journal of Radiation Research and Radiation Processing;2013-05
6 LIN Chen;AN Hongmei;Longhua Hospital,Shanghai University of Traditional Chinese Medicine;;Pharmacologic effects of Acorus Tatarinowii Schott on central nervous system[J];Journal of Changchun University of Traditional Chinese Medicine;2014-02
7 LI Yi;DENG Shengqi;REN Jing;Sichuan Industrial Institute of Antibiotics,Chengdu University;;Influence of Enhancers on Oral Absorption of Traditional Chinese Medicine Preparations[J];Journal of Chengdu University(Natural Science Edition);2014-03
8 QIU Lian-bo1,DING Gui-rong2,ZHOU Yan2,CHEN Chen3,DING Jun-wei1.1.Medical Team,93413 Force,Yongji 044500,China;2.Department of Radiation Medicine,College of Preventive Medicine,Fourth Military Medical University,Xi'an 710032,China;3.Department of Blood Transfusion,Xijing Hospital,Fourth Military Medical University,Xi'an 710033,China;The expression and significance of GFAP and PKC in the rat frontal cortex after electromagnetic pulse exposure[J];Chinese Journal of Disease Control & Prevention;2011-08
9 LI Xiang,PENG Rui-yun,HU Xiang-jun,WANG Shui-ming,GAO Ya-bing,WANG Li-feng,DONG Ji,ZHAO Li,CHANG Gong-min,WANG Xiao-min,SU Zhen-tao.Institution of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China;Changes and significance of occludin expression in rats with blood-brain barrier injury induced by microwave radiation[J];Medical Journal of Chinese People's Liberation Army;2011-07
10 PENG Rui-yun(Institute of Radiation Medicine,Academy of Military Medical Sciences,Beijing 100850,China);Potential solutions to brain injury induced by electromagnetic radiation and its protection[J];Military Medical Sciences;2011-05
China Proceedings of conference Full-text Database 1 Hits
1 ;The effect of Acorus gramineus in Kai-xin-san on the absorption of ginsenosides Rg1,Re and Rb1[A];[C];2009
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved