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Advance of Immunology Mechanism and Role of VE and Se in Host Defense Against Bovine Mastitis

DING Yue-yun, WANG Tian (College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China)  
Bovine mastitis is a kind of complicated disease with pathogens, and brought a large economy losses to bovine industry all over the world. Accumulating evidence shows that the incidence and severity of mastitis is related to the vitamin E and Se status of a dairy herd. VE and Se are essential nutrients that share common biological activities. Cows supplemented with both vitamin E and Se have lower incidence of clinical mastitis and shorter duration of clinical signs. A known physiological consequence of Se or VE deficiency is reduced polymorphonuclear cells (PMN) activity. This article summarized the role of VE and Se in host defense against mastitis, and clarified the immunology mechanisms of increased PMN activity by VE and Se.
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