Advance of Immunology Mechanism and Role of VE and Se in Host Defense Against Bovine Mastitis
DING Yue-yun, WANG Tian (College of Animal Science and Technology, Nanjing Agricultural University, Nanjing 210095, China)
Bovine mastitis is a kind of complicated disease with pathogens, and brought a large economy losses to bovine industry all over the world. Accumulating evidence shows that the incidence and severity of mastitis is related to the vitamin E and Se status of a dairy herd. VE and Se are essential nutrients that share common biological activities. Cows supplemented with both vitamin E and Se have lower incidence of clinical mastitis and shorter duration of clinical signs. A known physiological consequence of Se or VE deficiency is reduced polymorphonuclear cells (PMN) activity. This article summarized the role of VE and Se in host defense against mastitis, and clarified the immunology mechanisms of increased PMN activity by VE and Se.