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《Acta Ecologiae Animalis Domastici》 2006-06
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Dosage Compensation of Early Embryo and Its Effect on the Development of Mammals

WANG Zheng-chao,PAN Xiao-yan,PANG Xun-sheng (1.College of Animal Science and Technology,Nanjing Agricultural University, Nanjing 210095,China; 2.Anhui College of Science and Technology,Bengbu 233100,China)  
Dosage compensation is the process by which the levels of X-linked gene expression is equalized between the sexes.In mammals,it is achieved by random inactivating one of the two X chromosomes in the female.X inactivation starts at the X-inactivation center(XIC) and spreads throughout the chromosomes.The Xist gene maps to the XIC region on the X chromosome and is thought to be involved in the initiation of inactivation.X-linked gene expression in androgenones,gynogenones,parthenogenones and normal Embryos were analysed in this article;Whilst it also summaried the effect of X chromosome inactivation(XIC) on the development of early embryos in mammals,and reviewed the dosage compensation of early embryo and its effect on the development in mammals
【Fund】: 安徽省自然科学基金(03041203)资助
【CateGory Index】: Q344
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