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《Basic Medical Sciences and Clinics》 1988-03
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Dynamic Changes of Leukocytes and some Inflammatory Me-diators during Carrageenan-induced Pleurisy in Rats

Chen Xiang-yin Yan Yi-zhao Zhang Bao-ling and Xi Pin-xiang(Institute of Basic Medical Sciences, Beijing)  
42 male wistar rats, weighing 200-245g, were used in this investigation. Pleurisy was produced by injection of 1 % carrageenan 1 ml into pleural ca vity. The changes of leukocytes and some inflammatory mediators were ob-served. The results showed that exudate valume, neutrophils counts, β-gluc-uronidase and lysozyme activities in exudate were increased, TXB2 , 6-Keto -PGF1α elevated as well at 6 h after pleurisy. These changes were reached to maximum at 12-24h, and decresed to normal at 72h after pleurisy. The role of accumulation and activation of neutrophils and their production of inflammatory mediators such as lysosomal enzymes and arachidonic acid metabolites in pathogenesis of inflammation was discussed.
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【References】
Chinese Journal Full-text Database 1 Hits
1 LI Ping, LU YunBi, ZHOU HanLiang, CHEN JiQiang (Dept of Pharmacology, Medical School, Zhejiang University, Hangzhou 310031);Changes of phospholipase D activity of exudate leukocytes in rat carrageenan-induced pleurisy[J];CHINESE PHARMACOLOGICAL BULLETIN;2000-01
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Li He(Institute of Basic Medical Sciences, Beijing);The Effects of Electro-acupuncture on Exudate Volume and TXB2,6-Keto-PGF_(1α) Contents in Pleural Cavity after Carrageenin-Induced Pleurisy in Rats[J];Acta Academiae Medicinae Sinicae;1987-04
【Co-references】
Chinese Journal Full-text Database 2 Hits
1 Huang Yong; Wu Xinghong; Qureshi Imran Ahmad; Chen Huili(Department of Biochemistry, Public Health Ministry Key Lab of Glycoconjugate Research,School of Basic Medical Sciences, Shanghai Medical University, Shanghai 200032);DETERMINATION OF PHOSPHATIDYL CHOLINE SPECIFIC PHOSPHOLIPASE D USING ENZYME COUPLING COLORIMETRIC METHOD AND ITS APPLICATION[J];JOURNAL OF SHANGHAI MEDICA(UNIVERSITY);1997-05
2 LI Ping, ZHOU Han Liang, CHEN Ji Qiang (Department of Pharmacology, Zhejiang Medical University, Hangzhou 310031);Phospholipase D and Inflammation[J];PROGRESS IN PHYSIOLOGICAL SCIENCES;1999-02
【Secondary References】
Chinese Journal Full-text Database 3 Hits
1 Bai Jing, Sun Mingyu , Wang Shouyong, et al. (Disciplinary Division of TCM Formulas, Beijing University of Traditional Chinese Medicine,Beijing 100029);Effects of different ingredient-combinations of Xiaochaihu Decoction on the rat model of pleuritis induced by carrageenan[J];Journal of Beijing University of Traditional Chinese Medicine;2005-01
2 LU Yun-Bi, JIANG Bo, ZHOU Han-Liang (Department of Pharmacology, School of Medical Science, Zhejiang University, Hangzhou 310031, China);Effects of salbutamol and sodium cromoglicate on phospholipase D activity during the degranulation of rat peritoneal mast cell[J];Chinese Journal of Pharmacology and Toxicology;2001-05
3 SUN Ming-yu, XIE Ming, ZHANG Na, et al Beijing University of Chinese Medicine, Beijing (100029);Effect of Xiaochaihu Decoction and Different Herbal Formulations of Its Components on Cytokines of Carrageenan Induced Pleuritis in Rats[J];Chinese Journal of Integrated Traditional and Western Medicine;2004-07
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Shi Yiqing,Li Zenjia, Ma Kuirong,Cheng Jinxuan,Yan Meifang, Wang Shurong,Jiang Zenji,Duan Jinhong and Wang Zhengang(Institute of Basic Medical Sciences, Beijing) General Hospital of PLA,Beijing Institute of Zoology, Academic Sinica, Beijing Department of Pharmacology, Shandong Traditional Medical College;Radioimmunoassay of 6-keto-PGF1a[J];Acta Academiae Medicinae Sinicae;1986-04
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