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《BASIC MEDICAL SCIENCES AND CLINICS》 1995-02
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Protective Effects of 654-2 on Myocardial Ischemic reperfusion Injury in Rat

ChangYingzi Su Jingyi(Pathophysiological Department,Cardiovascular Research Basic Institute, Beijing Medical University)  
y using Langendorf’s perfusion of rat heart,the protective effects of 654-2 on myocardialischemic reperfusion injury resulted from calcium concentration alteration in perfusion fluid wasinvestigated.The results showed that 654-2 significantly prevented ischemic and ischemia -reper-fusion injury caused by Ca ̄2+) concentration alterations in perfusion fluid given at the beginning ofpreperfusionand reperfusion. The effect is probably realized by its membrane stabilizing actionandregulation of intracellular Ca ̄(2+) homeostasis.
【CateGory Index】: R541.405
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