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《Pharmaceutical Journal of Chinese People's Liberation Army》 2001-06
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The Basic Study on Nonionic Surfactant Microemulsion

WANG Xiao Li ①,JIANG Xue Tao,LI Gan Zuo ②,MU Jian Hai ② ( ① Department of Pharmacy,The Second Military Medical University,Shanghai 200433) ( ② Key Laboratory for Colloid and Interface Science of State Education Ministory,Shandong Universi  
Aim To study the formation and the effect factors of microemulsion phase at 25℃ for system containing nonionic surfactant.Methods The effects of surfactants,cosurfactants,oils and additives on microemulsion region were examined by using the method of titration to prepare the pseudoternary phase diagram.Results The formation of microemulsion was dependent on the HLB values of surfactants,the nature of oils and cosurfactants,the weight ratio of surfactant to cosurfactant and the type of additives in the water phase and also the variation of temperature.Conclusions Microemulsions could be prepared by using nonionic surfactants when the suitable formulations were selected.
【CateGory Index】: O648
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