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《Pharmaceutical Journal of Chinese People's Liberation Army》 2004-04
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The Effect of Puerarin on Diuresis

ZHU Qing-Lei ①,HAN Hui-Rong ②,HE Ai-Xia ③,LU Xin-Ran ② ( ①Institute of Geriatric Cardiology,General Hospital of People's Liberation Army,Beijing 100853 China) ( ②Applied Pharmacology Laboratory of Weifang Medical College,Weifang 261042,Shangdong China) ( ③Department of Anesthesiology,Fuwai Cardiovascular Hospital,Beijing 100037 China)  
Aim To study the effect of Puerarin (Pue) on diuresis.Methods The urine volume and the renal blood flow (RBF) were determined by ureteral cannula and electromagnetic flowmeter,respectively,as well as the contents of urine sodium,potassium,and chloride were assayed by flame photometry and argentometry,respectively.Results Pue at the dose of 40 and 80mg·kg -1 iv could increase the urine volume and the contents of urine sodium,potassium,and chloride.Moreover the increase of the contents of urine sodium and chloride was much greater than that of potassium.However,the renal blood flow kept unchanged.Conclusion It is concluded that Pue is effective on diuresis.
【CateGory Index】: R285
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