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《Pharmaceutical Journal of Chinese People's Liberation Army》 2011-03
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A Preliminary Study on the Anti-tumor Activity of Alcohol Extracts of Pini Pollen

LI Wen-wen①,CHEN Cai-fa②,LI Yue③,ZHU Yu-jie①①College of Biological Science,②Key Laboratory of Biotechnology for Medicinal Plants of Jiangsu province,Xuzhou Normal University,Xuzhou221116,China;③No.2 Attached Elementary School,Jiangsu China Lianyungang Teachers College,Lianyungang222023,China  
Objective To investigate the anti-tumor activities of alcohol extracts of Pini Pollen in vivo and in vitro.Methods In vitro test:the MTT method was used to determine the inhibitory effect of alcohol extracts of Pollen Pini on 247,HCT116,HeLa and K293.In vivo test:mice with Lewis lung carcinoma were used in this study,The weight of the tumor,thymus,spleen,the tumor inhibitory rate and immune organ index in each group were calculated.Results Alcohol extracts of Pollen Pini had obvious cytotoxicity to various tumor cells but less cytotoxicity to normal cell K293,Capable of significant inhibition on the growth of Lewis lung carcinoma transplanted tumor and can increase the thymus and spleen index of mice.Conclusion Alcohol extracts of Pollen Pini can effectively inhibit tumor and protect immune organs.
【Fund】: 江苏省高校自然科学基金项目 No.07KJD360212
【CateGory Index】: R285.5
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【Citations】
Chinese Journal Full-text Database 6 Hits
1 He Xiaoyan,Sun Xueyuan,Yu Zhiyang(Department of Biology,Tonghua Teachers College,Tonghua 134002,P.R.China);Effective Components and Pharmacological Function of Pine Pollen[J];Journal of Northeast Forestry University;2007-09
2 CHEN xiao-feng, GU Zhen-leng, LIANG Zhong-qin (Department of Pharmacology, Medical School,Suzhou University;Suzhou Institute of Chinese Materia Medica,Suzhou 215007,China);Antitumor Effect of the Extract of Fagopyrum Cymosum[J];Acta Academiae Medicinae Suzhou;2001-01
3 DING Zhi-Shan, GAO Cheng-Xian, CHEN Ni-Pi, LIANG Bing-Bing, YUAN Wei, WO Xing-De (Institute of Molecular Medicine,Zhejiang Traditional Chinese Medical College ,Hangzhou 310053);Effects of curcumin: antiangiogenesis and induction of SMMC-7721 cell apoptosis[J];Chinese Pharmacological Bulletin;2003-02
4 LiuKe -wu1,ZhaoXin -ping1,LiuXiao -wen1, ZhangBing1,ZhangHong -yuan1,WeiWei1,MinLi -e1,YuDong1,LiuXin2 . (1 .collegeofLifeScience ,SichuanUniversity , 61 0 0 64 ;2 .collegeofpharmacon ,ChengduUniversity ofTraditionalChineseMedicine,61 0 0 75 );Mechanism of Pollen’s Physiological Active Substances and Trace Ele me nts effecting Metabolism[J];APICULTURAL SCIENCE AND TECHNOLOGY;2000-01
5 MA Bing 1, XIANG Yang 1, LI Tao 1, YU He ming 2, LI Xue jun 1 (1 Department of Pharmacology, School of Basic Medical Sciences, Peking University, Beijing 100083, China; 2. National Research Institute for Family Planning, Beijing 100081, China);Inhibitory effects of Alisma orientalis on spontaneous metastasis of Lewis lung carcinoma and its mechanism[J];Chinese Traditional and Herbal Drugs;2003-08
6 CHEN Gang1, XU Xiao-yu1, YAN Peng-ke2, LIAO Duan-fang2 (1.School of Chinese Traditional Medicine, Chongqing University of Medical Sciences, Chongqing 400050, China; 2. Department of Pharmacology, Nanhua University, Hengyang 410016, China);Relationship between effect of tetramethylpyrazine and Danshen on inhibiting Lewis lung carcinoma growth and tumor angiogenesis[J];Chinese Traditional and Herbal Drugs;2004-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Chen Liangliang,Huang JianfeiZhejiang Provincial TCM Hospital,Hangzhou(310006);Review on the Research of the Effect of Danshen and Its Extract on Tumor Metastasis[J];Journal of Zhejiang University of Traditional Chinese Medicine;2006-04
2 Ye Qing,Chen Peifeng Zhejiang Chinese Medical University,Hangzhou(310053);Review on Tumor Vessel Production Inhibited by Chinese Drugs Extract[J];Journal of Zhejiang University of Traditional Chinese Medicine;2007-04
3 YIN Long,XU Liang,HU Ge,SUO Zhan-wei,DUAN Hui-qin,YANG Zuo-jun,GAO Li-yun,MU Xiang(Department of Animal Science and Technology, Beijing Agricultural College, Beijing 102206,China);Advance in Herb Medicine and Its Bioactive Compounts in Antitumor’s Mechanism[J];Progress in Veterinary Medicine;2006-01
4 WU Jing-jing,HUANG Pei-huang,ZHU Liang,LIN Fu-lan(College of Light Industry and Food Sciences,South China University of Technology,Guangzhou 510640,China);Anti-fatigue Effects of Flavone in Pinus Massoniana Pollen on Mice[J];Modern Food Science and Technology;2010-08
5 LONG Sang,SHI Guo-rong (College of Science,Hunan Agricultural University,Changsha 410128,China);Research Progress on Pharmacological Activities of Rhizoma Fagopyrum Dibotryis[J];Journal of Hunan Environment-Biological Polytechnic;2007-03
6 HU Hui-qun,TANG Xue-yuan,PAN Yun-liang(Department of Oncology,the Third Xiangya Hospital,Central South University,Changsha,Hunan 410013,China);Inhibitory Effect of Tetramethylpyrazine in Combination With Cisplatin on Growth and Metastasis of Lewis Lung Carcinoma in Mice[J];Journal of Nanhua University(Medical Edition);2008-01
7 CHEN Cai-Fa②,MIAO Jin,LI Jing-Hui,ZHENG Wei-Fa(②Key Laboratory for Biotechnology on Medicinal Plants of Jiangsu Province,Xuzhou Normal University,Xuzhou 221116,Jiangsu China);The Inhibitory Effect of Pollen Typhae Extract on Lewis Lung Carcinoma[J];Pharmaceutical Journal of Chinese People's Liberation Army;2008-03
8 YU Jian-hua(Medical College of Shaoguan College,Shaoguan 512026,China);Effects of curcumin on proliferation of nasopharyngeal carcinoma cell line(CNE-2Z-H5)[J];Journal of Jinggangshan University;2007-06
9 Chen Gang Xu Xiaoyu Feng Jundong(College of Traditional Chinese Medicine, Chongqing University of Medical Sciences, Chongqing 400050 );Mechanism of inhibition effect of ligustrazine on synovium lesion in rats with arthritis induced by collagen II[J];Journal of Beijing University of Traditional Chinese Medicine;2005-03
10 HONG Xing-Qiu,HUANG Yan-Fen1,DING Zhi-San,LIU Yan,and LIU Hai-Long(Life Science Institute,Zhejiang Chinese Medical University,hangzhou 310053,China);The Effects of Ramification of Curcumin Hydrolyzed on Proliferation of Vascular Smooth Muscle Cells and Expression of Low Density Lipoprotein Receptor[J];Chinese Journal of Arteriosclerosis;2007-04
China Proceedings of conference Full-text Database 2 Hits
1 QIAN Ying, FAN Chun-lei, DOU Xiao-bing, HU Ling-fen, Wo Xing-de (Life Science Department, Zhejiang College of TCM, Hangzhou 310053);Effect of Curcumin on Sterol Regulatory Report System in HEK-293[A];[C];2005
2 Wang Jinnian~1,He Yuyou~2,Qin Guofeng~3,Chu Deyu~4,Hu Jiansheng~5 (1.Zhejiang Chun-an Forestry Bureau,Chun-an,Zhejiang 311700;2.Pine Pollen Research and Development Center,CAF,Fuyang,Zhejiang,311400;3.Subtropical Forestry Research Institute,CAF, Fuyang,Zhejiang,311400;4.Laoshan Stand,Xinanjiang Development Company,Chun-an,Zhejiang, 311700;5.Jinfengxiang Forest Station,Chun-an,Zhejiang,311701);Observe on the Mature Period of Masson Pine Male Cones and its Climatic Impact[A];[C];2010
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 Huang Renmin Yuan Shulan Song Yi, et al.The Institute of Cancer Research, West China University of Medical Science Chengdu, 610041;Apoptosis of human leukemic HL-60 cells induced by Tanshinone ⅡA[J];CHINESE JOURNAL OF CANCER;1998-03
2 ZHANG Ping; HAO Hongying; WANG Shenwu; ZHANG Yijun; LU Daopei (Institute of Hematology, Beijing Medical University, Beijing 100034);THE EXPRESSION OF BCL-2 GENE DURING APOPTOSIS OF HL-60 CELLS INDUCED BY ETOPSIDE[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1997-05
3 PAN Yao qian, YU Yan, XIA Zhi ping (Faculty of Animals Science, Quartermaster University of PLA, Changchun, 130062, China);The Common Methods for Detecting Apoptosis[J];Progress In Veterinary Medicine;2001-02
4 Xiao Jianchun;Study on Extracting method of active ingrident from Masson pine pollen[J];Guangzhou Food Science and Technology;2001-02
5 Zhao Yan Cao Jin Zhu Hecheng (Tea and Health Laboratory, Hunan Medical University, Changsha 410078);INDUCTION OF APOPTOSIS BY TEA POLYPHENOLS IN MGC CELLS[J];BULLETIN OF HUNAN MEDICAL UNIVERSITY;1997-05
6 LIU Xie, ZHANG Chi, BAO Liu—xing, et al. (Jiangsu Province Center for Disease Control and Prevention, Nanjing 210009,China);Study on the protective effect of pine pollen on alcohol-induced acute hepatic injury[J];Jiangsu Preventive Medicine;2005-02
7 CONG Tao,ZHAO Lin,BAO Shan-fen(Department of Nutrition,PLA General Hospital,Beijing 100853,China);Study on the treatment of rats with benign prostatic hypertrophy by Masson Pine Pollen[J];Academic Journal of Pla Postgraduate Medical School;2005-05
8 Wang Kai-Fa Zhang Yu-Lan (Research Center of Pollen Applying, Tongji University, Shanghai, 200092);STUDY ON THE VITAMIN POLLEN[J];JOURNAL OF BEE;1997-02
9 LIU Xie, HU Qi zhi, LI Xiao ning, BAO Liu xing (Jiangsu Provincial Center for Disease Prevention and Control, Nanjing 210009, China);Study on the antifatigue function of pine pollen[J];Chinese Journal of Biochemical Pharmaceutics;2004-03
10 ZHAO Li xin, YU Lu (1.Graduate Team,First Military Medical University,Guangzhou 510515,China; 2.Department of Nephrology,the PLA 305 Hospital,Beijing 100017,China);Experimental study on effects of pollenpini on anti-aging[J];Railway Medical Journal;2004-02
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