Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Medical Journal of Chinese People's Liberation Army》 2002-06
Add to Favorite Get Latest Update

ACCELERATING THE REVASCULARIZATION OF TISSUE ENGINEERED BONE WITH FASCIA FLAP IN VIVO:AN EXPERIMENTAL STUDY

Chen Bin, Pei Guoxian, Wang Ke et al. Department of Orthopaedics and Traumatology, Nanfang Hospital, First Military Medical University, Guangzhou 510515  
To study the ability to repair the large segment defect of weight bearing bone of caprine with tissue engineered bone and the effect of revascularization of tissue engineered bone with fascia flap in vivo. 27 caprines were divided into three groups: group A (the defect was filled with coral hydroxyapatite CHAP); group B (the defect was filled with CHAP + bone marrow stroma cell BMSc); group C (the defect was filled with CHAP +BMSc + fascia flap). After BMSc was cultured and induced, CHAP in group B and C was combined with it. A 20mm bone defect was made and fixed with 93mm AO dynamic compression plate of levo tibia, and implanted with different materials as described above. Radionuclide bone imaging was used to monitor the revascularization of the implants 2, 4, 8 weeks after operation. X ray examination, optical density index of X ray film, HE staining of the implants were performed 4, 8, 12 weeks after operation to evaluate the bone regeneration and bone defect repairing effect. VG staining was an ideal method to judge the revascularization of implants. Group A showed some trace of bone regeneration. Group B manifested a good ability to repair the defect. In group C, with the assistance of fascia flap which gives more chance to make implants get more nutrient, the ability to repair the defect was quite strong. Fascia flap can accelerate the revascularization process of tissue engineered bone, and by this way, it augments the ability of tissue engineered bone to repair the large bone defect of caprine.
【Fund】: 国家重点基础研究发展规划 (编号G1 9990 543 0 9);; 全军医学科研“十五”计划重大项目 (编号 0 1Z0 4 5);; 广东省自然科学基金 (编号 990 4 1 4 );; 广东省团队项目 (编号 1 0 71 71 41A1 2J1 5)资助课题
【CateGory Index】: R318.0
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 8 Hits
1 Cui Jiande, Pei Guoxian, Jin Dan, et al. Department of Orthopaedics and Traumatology, Nanfang Hospital, Nanfang Medical University, Guangzhou 510515, China;Changes of CGRP and NPY expression in tissue-engineered bone with fascia flap[J];Medical Journal of Chinese People's Liberation Army;2008-06
2 ;Tissue engineered bone technique and its application in mandible defect reconstruction[J];Chinese Journal of Dental Materials and Devices;2005-02
3 ZHAO Ming-dong1 YIN Wang-ping1 DONG Jian2 (1Department of orthopaedics,Jinshan Hospital,Fudan University,Shanghai,200540,China;2Department of orthopaedics,Zhongshan Hospital,Fudan University,Shanghai,200032,China);Advances in therapy of bone defects with vascular bundle implantation[J];Fudan University Journal of Medical Sciences;2007-04
4 Wang Yu-xue, Bi Zheng-gang, Yang Cheng-Lin, Department of Orthopaedics, First Clinical Medical College, Harbin Medical University, Harbin 150001, Heilongjiang Province, China;Revascularization of tissue engineered bone[J];Chinese Journal of Clinical Rehabilitation;2005-30
5 PEI Guo xian, WEI Kuan hai Department of Orthopaedics and Traumatology, Nanfang Hospital, The First Military Medical University, Guangzhou 510515, China;Application of microsurgery in fabrication of vascularized engineered tissue[J];Chinese Journal of Orthopaedic Trauma;2004-04
6 GU Zu-chao1, LI Qi-hong2, ZHAO Yu-feng2, YANG Liu2, XU Jian-zhong2 1Department of Orthopaedics, The First People's Hospital of Chengdu, Chengdu 610016, China 2Department of Orthopaedics, Xinan Hospital, Third Military Medical University, Chongqing 400038, China Supported by State Foundation of Natural Sciences in China (3980100) and Foundation of Military Medical Science and Technology Research (01Z072) Corresponding author: LI Qi hong;An experimental study on the marrow stromal cells and biomaterial composites in repair of segmental defects of rabbit ulna[J];Chinese Journal of Orthopaedic Trauma;2004-06
7 WANG Qun-li, PEI Guo-xian, ZENG Xian-li, JIN Dan, WEI Kuan-hai, REN Gao-hongDepartment of Orthopaedics and Traumatology,Nanfang Hospital, The First Military Medical University,Key Laboratory of Tissue Construction and Detection of Guangdong,Guangzhou 510515, ChinaSupported by Chinese National High Technology Development Program(2003AA205010), State Foundation for Natural Sciences in China(30300367),Guangzhou Municipal Grants for Significant Projects of Science and Technology(200221-0038);Culture of the BMSCs of adult rhesus in vitro[J];Chinese Journal of Orthopaedic Trauma;2004-07
8 ZENG Xian li, PEI Guo xian, JIN Dan, TANG Guang hui, WANG Xue ming, LIU Xiao xia, ZENG Jun ling, ZHANG Wen gaoDepartment of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Key Laboratory of Tissue Construction and Detection of Guangdong Province, Guangzhou 510515, ChinaSupported by Chinese National High Technology Development Program (2003AA205010), State Foundation for Natural Sciences in China (30300367), Guangzhou Municipal Grants for Significant Projects of Science and Technology (200221 0038)Corresponding author: PEI Guo xian;An experimental pattern designed to prepare a kind of vascularized engineered bone in vivo for repairing tibial defect in rhesus: establishment and observation[J];Chinese Journal of Orthopaedic Trauma;2005-04
【Citations】
Chinese Journal Full-text Database 1 Hits
1 JIN Dan, PEI Guo- xian, CHEN Bin,et al.Nanfang hospital, The First Military Medical University, Guangzhou 510515, China;Angiogenesis and neurotization study of bone tissue engineering[J];Modern Rehabilitation;2001-16
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 WANG Qiu-shi, PEI Guo-xian, JINAG Shan, ZHAO Pei-ran, LIANG Shuang-wu, DAI Jin-liang, CUI Jian-de Department of Orthopedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;Effect of rabbit peripheral sensory and motor nerve homogenates on the proliferation and calcification of rabbit osteoblasts in vitro[J];Journal of Southern Medical University;2008-05
2 SUN An-ke,PEI Guo-xian(Center of Orthopaedics and Traumatology of PLA,Nanfang Hospital,The First Military Medical University,Guangzhou 510515,China);The problems and developmental way of tissue engineering[J];Foreign Medical Biomedical Engineering Fascicle;2003-05
3 Wang Yonggang, Pei Guoxian. Department of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;Experimental study on the vascularization of tissue-engineered bone with vascular bundle graft[J];Medical Journal of Chinese People's Liberation Army;2007-01
4 Xiao-Jun Duan,Liu Yang,Yue Zhou;Progress and strategy study of facilitating tissue engineering and blood vessel of bone[J];Chinese Journal of Clinical Rehabilitation;2003-26
5 Zhang Yuan-ping1, Cui Ji-xiu1, Li Qing-he1, Ma Zheng-kai1, Wang Yong-gang2, Pei Guo-xian2 1Department of Orthopaedics, Fourth Convalescent District of Lintong Sanatorium, Lanzhou Military Area Command of Chinese PLA, Xi'an 710600, Shaanxi Province, China; 2Department of Orthopaedics and Traumatology, Nanfang Hospital of Southern Medical University, Guangzhou 510515, Guangdong Province, China;Osteogenesis effects of tissue-engineered bone after sensory and motor nerve tract implantations[J];Chinese Journal of Clinical Rehabilitation;2006-21
6 PEI Guo-xian,JIN Dan Department of Orthopedics and Traumatology, Nanfang Hospital,First Military M edical University, Guangzhou 510515, China Supported by Chinese Key National Basic Scientific Research and Development Pr ograms(G1999054309), Chinese National High Technology Development Program(200 3AA205010);Advances in tissue engineering of bone[J];Chinese Journal of Orthopaedic Trauma;2004-01
7 ZHANG Yuan-ping 1 ,CUI Ji-xiu 2 ,PEI Guo-xian 1 ,WANG Yong-gang 1 ,JIN Dan 1 ,QIN Yu 1 ,CHEN Bin 1 ,WEI Kuan-hai 1 1 Department of Orthopaedics and Traumatology,Nanfang Hospital,Southern Medical University,Guangzhou510515,China 2 The First Department,The First Army Sanatorium,Lintong,Xi ' an 710600,China;A primary study on reconstruction of neurotization of tissue engineered bone[J];Chinese Journal of Orthopaedic Trauma;2005-01
8 WANG Yong-gang, PEI Guo-xianDepartment of Orthopaedics and Traumatology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, ChinaSupported by Chinese National Program of Basic Scientific Research Development (G1999054309)Corresponding author: PEI Guo-xian;Effects of peripheral nerve system on bone tissue engineering[J];Chinese Journal of Orthopaedic Trauma;2005-07
9 JIN Dan,CHEN Bin,PEI Guo-xian,et al.Department of Orthopaedics and Traumatology,Nanfang Hospital,Nanfang Medical University,Guangzhou 510515,China;Accelerating osteogenesis and revascularization of tissue engineered bone using fascia flap in Chinese goats tibia defect repairing[J];Chinese Journal of Experimental Surgery;2005-03
10 XU Jinghong1, WANG Huiming2, LI Youqin2, TAN Weiqiang1, LIN Jun2, WANG Wei3. 1Department of Plastic Surgery, 2Department of Stomatology, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou Zhejiang, 310003, P. R. China; 3Department of Plastic Surgery, Shanghai Ninth People's Hospital, Medical College of Shanghai Jiaotong University.;EXPERIMENTAL STUDY ON REPAIRING COMPOSITE DEFECT OF MANDIBLE AND SKIN BY PREFABRICAT-ED MUSCULOCUTANEOUS FLAP INCLUDING ECTOPIC BONE[J];Chinese Journal of Reparative and Reconstructive Surgery;2008-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 HU Qun 1,NING Tao 1,SU Xiu Lan 2,WANG Wen Li 2,KE Yang 1 (1. Laboratory of Cytogenetics, Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100034, China; 2. Inner Mongolia Medical College);Improvement of chick chorioallantoic membrane technique[J];Journal of Beijing Medical University;2001-04
2 Chu Chenglin et al;Advancement of Hydroxyapatite(HA)Biological Composites[J];Materials Review;1999-02
3 Dai Zhaochen Liu Yu Shi Xiaoli Huang Ying Li Qiushan (Institute of Aeronautical Materials,Beijing);An Investigation on Preparation and Properties of Two Phase Porous Calcium Phosphate Bioceramics[J];Journal of Materials Engineering;1997-01
4 QIN Hui,XU Jian-zhong,WANG Xu-qian,et al. (Department of Orthopaedics,Southwest Hospital,the Third Military Medical University,Chongqing 400038,China);Experimental study of formatting tissue engineering bone with different densities of seeding cells in vitro[J];Chongqing Medical Journal;2004-10
5 GAO Chun-yang,LI Qi-hong,JIAN Yue-kui,et al.(Department of Orthopedics,Southwest Hospital,the Third Military Medical University,Chongqing 400038,China);Experimental study on properties of xenogeneic deproteinised cancellous bone as scaffold of bone tissue engineering[J];Chongqing Medical Journal;2005-12
6 JIANG Zong Lai, CONG Xing Zhong, LI Yu Quan, ZHANG Yan, CHEN Shuang Hong,ZHANG Chuan Sen, YANG Xiang Qun (Department of Anatomy, Institute of Biomedical Engineering, Department of Basic Medicine, Second Military Medical University, Shanghai 200433,;Morphology of endothelial cells co-cultured with vascular smooth muscle cells under shear stress[J];Academic Journal of Second Military Medical University;2000-11
7 DAI Gang, SHI Zong-li, LI Qi-hong, LI Chong-an (Department of Orthopedics, Southwest Hospital, Third Military Medical University, Chongqing 400038, China);Preparation and properties of novel scaffold composites for bone and cartilage tissue engineering[J];Acta Academiae Medicine Militaris Tertiae;2002-05
8 GU Zu-chao, LI Qi-hong, ZHAO Yu-feng, ZHOU Hong-xing, ZHOU Qiang (Department of Orthopedics, Southwest Hospital, Third Military Medical University, Chongqing 400038,China);Osteogenic property of cultured rabbit marrow stromal cells under condition of bone induction[J];Acta Academiae Medicine Militaris Tertiae;2002-05
9 WANG Wan-Ming, HU Yun-Yu, ZHAO Guang-Yue, LU Rang, YANG GuangInstitute of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710033;Investigation of the growth characteristics of cultured rabbit marrow stromal cells[J];Journal of The Fourth Military Medical University;1998-02
10 WU Xiao-Lin~1, LI Dong-Min~1,MA De-Mao~2, ZHANG Xiao-Tian~1, HUANG Shi~3, SONG Tian-Bao~1 ~1Department of Human Anatomy, Histology and Embryology, ~37-years Student, Grade 2003, Medical School, Xi'an Jiaotong University, Xi'an 710061, China, ~2Department of Cardiothoracic Surgery, Xi'an Railway Central Hospital, Xi'an 710054, China;Induced differentiation and labeling of bone marrow-derived mesenchymal stem cells in vitro[J];Journal of the Fourth Military Medical University;2006-21
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 ZHANG Jian,HU min,ZHANG Wen-yi,XIAO Hong-xi.Stomatological hospital Tianjin Medical University,Tianjin 300070,China;Experiment study of repairing mandibular defects with compound of tissue engineering bone and vascular endothelial cells[J];Beijing Journal of Stomatology;2008-05
2 WANG Qun-li1, PEI Guo-xian2, YUN Xiong1, JIN Dan2, WEI Kuan-hai2, REN Gao-hong2 1Department of Orthopedics, 187 Central Hospital of PLA, Haikou 571159, China; 2Department of Trauma Orthopedics, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China;Green fluorescent protein as atracer of bone marrow stromal cells in bone tissue engineering in rhesus[J];Journal of Southern Medical University;2007-02
3 ;Review:Biodental material research (2001-2006)[J];Chinese Journal of Dental Materials and Devices;2007-01
4 DONG Xiao-peng,WANG Rui-xue(Chengdu University of TCM,Chengdu 610075,Sichuan,China);Research progress of the Bone Marrow Stem cells for Treating common Orthopedic Disease[J];Journal of Liaoning University of Traditional Chinese Medicine;2009-05
5 CHEN Tao,LI Ning-yi (The affiliated Hospital of Medical College,Qingdao University,Qingdao 266003,P.R.China);Construction of Vascularization of tissue engineered bone and its application in the reanstructive surgery of experimental[J];Shandong Medical Journal;2009-07
6 ZHAO Ming-dong1 YIN Wang-ping1 DONG Jian2 (1Department of orthopaedics,Jinshan Hospital,Fudan University,Shanghai,200540,China;2Department of orthopaedics,Zhongshan Hospital,Fudan University,Shanghai,200032,China);Advances in therapy of bone defects with vascular bundle implantation[J];Fudan University Journal of Medical Sciences;2007-04
7 Chengde Medical College(Chengde 067000) Feng Lixin Wang Dong Xiao Guizhi et al;Study of the isolation,culture and growth characteristics of rabbit bone marrow-derived mesenchymal stem cells in vitro[J];Shaanxi Medical Journal;2007-03
8 TENG Donghui, SUN Yuanming, YANG Xueqi, YANG Fujun, LI Heda, XIA Yulian, WANG Shuxing,LIU Zongli,LI Yumin The First Central Hospital,Tianjin 300192,China;The Experiment Research of Auto-osteoblast and Allogeneic Bone Compound Transplant[J];Tianjing Medical Journal;2005-09
9 Xu Zhan-wang1,Zhang Jian-xin1,Xu Bo2,Zhang Peng3,Tan Guo-qing4,1Department of Orthopedics,Affiliated Hospital,Shandong University of Traditional Chinese Medicine,Jinan 250011,Shandong Province,China; 2Medical College of Suzhou University, Suzhou 215007, Jiangsu Province, China;3Shandong University of Traditional Chinese Medicine,Jinan 250014, Shandong Province, China;Characteristics of operational technique for in vitro culture of bone marrow stromal cells of rabbits[J];Chinese Journal of Clinical Rehabilitation;2005-22
10 Wang QL, Pei GX, Yun X, Jin D, Wei KH, Ren GH 1Department of Orthopaedics, the 187 Central Hospital of Chinese PLA, Haikou 571159, Hainan Province, China; 2Department of Orthopaedics and Trauma, Nanfang Hospital, Southern Medical University, Guangzhou 510515, Guangdong Province, China;Biological safety of tissue-engineered bone constructed in rhesus[J];Journal of Clinical Rehabilitative Tissue Engineering Research;2007-19
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 XIAO Yang,JIAO Bing Hua,MIAO Hui Nan(Department of Molecucular Toxicology,Second Military Medical University,Shanghai 200433,China).;Progress in Vascular Endothelial Growth Factor.[J];PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS;2000-02
2 SHANG Qing-xin,CAO Yi-lin,ZHANG Di-sheng. Tissue Engineering Center,Shanghai Second Medical University,Shanghai 200235,China;The new bioengineering subject-tissue engineering[J];Modern Rehabilitation;2001-12
3 CHEN Bin, PEI Guo-xian. Department of Traumatology and Orthopediatry,Nanfang Hospital,The First Military Medical University,Guangzhou 510515,China;The standard of clinical application of tissue engineering[J];Modern Rehabilitation;2001-12
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved