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《Medical Journal of Chinese People's Liberation Army》 2004-09
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Study on the injury effect of EMP on Rhesus monkey eye

Jiang tao, Wang dewen, Zhang Jian et al . Institute of Radiation Medicine, Academy of Military Medical Sciences,Beijing 100850, China  
Objective To study the effect of EMP on optical system, Rhesus monkeys were irradiated with EMP, and the pathological changes in their cornea, lens, and retina were observed by microscopy. Methods Rhesus monkeys were irradiated with 6×10 4 V/m of EMP, and Feulgen, AgNOR, PI staining and LSCM, image analysis were all used to detect and analyze the pathological changes. Results AgNOR and DNA content in the lens epithelial cells of dead monkeys decreased at day 30 after irradiation, and they increased at day 136, 265, and 365 after irradiation. The sensitivity to EMP injury are as follows: lenscornearetina. Posterior capsular edema and vacuoles were found. The main complication of lens injury was cataract. Conclusions High power EMP may cause serious injuries to optical system. Lens is the most sensitive organ to EMP injury, and may lead to cataract
【Fund】: 全军医学科研“十五”计划指令性课题基金资助 (编号 0 1L0 2 3)
【CateGory Index】: R779.12
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【Co-citations】
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1 LI Yang, SONG Liang-Wen, PENG Rui-Yun, WANG De-Wen, JIN Mei-Hong, GAO Ya-Bing, MA Jun-Jie Department of Experimental Pathology, Beijing Institute of Radiation Medicine, Beijing, 100850, P. R. China;Effects of SB203580 and WP631 on Smad Signal Transduction Pathway in Lung Fibroblasts after Irradiation[J];Chinese Journal of Cancer;2008-07
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