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《Chinese Journal of Family Planning》 2005-01
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The Pharmacodynamic Studies of the Leaves of Disospyros Kaki for Treatment of Abnormal Uterine Bleeding

Wang shusong, Xu duo,Cai wenjuan, et al. Hebei Research Institute of Family Planning, Shijiazhuang 050071  
Objective: To explore the effect of the Leaves of Disospyros kaki on treatment of abnormal uterine bleeding. Methods: Pharmacodynamic studies of animal were adopted. Results:(1)the leaves of Disospyros kaki reduced the bleeding time and coagulation time of rats.(2)it increased the contraction of uterine muscle of normal and pregnant mice in vitro, promoted the contraction of Uterine muscle of rabbit in vivo.(3)it had obvious inhibitory effect on ear swelling raised by dimethylbenzene and vola pedis swelling raised by agar. It diminished uterine inflammation by plastic tube.(4)it had no effect on the uterine and ovary development. Conclusion: the Leaves of Disospyros kaki could be used for hemostasis, diminish inflammation and increase the contraction of uterus.
【Fund】: 河北省科技攻关项目 (972 761 55D)
【CateGory Index】: R285
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