Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Emergenoy Medicine》 2000-06
Add to Favorite Get Latest Update

Influence of rotundine on NO、ET-1 and energy metabolism after acute brain injury resulted from complete cerebral ischemia reperfusion in the rats

Tang Yan,Yang Guangtian,Jiang Chonghui.Department of Emergency,DongFeng Central Hospital,Shiyan 442008  
Objective:To find the influence of Rotundine(L THP) on NO、ET 1、ATP and Lactate in rat brain tissues after the global ischemia reperfusion and to investigate protective effects of L THP.Methods:The four vessel occlusion model was made as described by Pulsinelli Brierlog in Sprange Daweley rats.The influences of L THP on NO、ET 1 and energy metabolism during the reperfusion period was observed.Results:L THP can suppress the marked increase of NO、ET 1 and lactate in the early stage of reperfusion,and also improve the contents of ATP.Conclusion:L THP provides remarkable protection against cerebral ischemia reperfusion damage.Its mechanisms may be through its influence on NO、ET 1 and energy metabolism.
【CateGory Index】: R743
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 10 Hits
1 LU Shu -lai1,CHEN Li 2,XING Fu -bao1,CHENG Guo -xiang1(1.Materials Science and Engineerin g College,Tianjin University,Tian jin 300072,China;2.National Engineering and Technology Research Center for Agricultura l Products Freshness Protection,Ti anjin 300;Latest Advancse of Application of Chitosan in Drug Research[J];Storage and Process;2002-03
2 JIANG Chonghui,YANG Guangtian,TANG Yan,et al.Department of Emergency,Zhongshan City Peoples Hospital,Zhong Shan 528400,China;Effects of L-tetrahydropalmatine on neuronal apoptosis during cerebral ischemia/reperfusion in rats[J];Journal of Emergenoy Medicine;2001-06
3 JIANG Chonghui,HOU De ren,YANG Guangtian,et al.Zhongshan City Peoples Hospital,Zhong shan 528400,China;Effets of L-tetrahydropalmatine on ICAM-1 expression in cerebral microvascular endothelial cells during hypoxia-reoxygenation[J];Journal of Emergenoy Medicine;2003-01
4 WANG Min,CHEN Jian-ying,LIUJie (Institue of Biopharmaceuticals of Shandong Province, Jinan 250108 ,China);Overview of chitosan application in medicine[J];;2005-08
5 WANG Ya-hong, QU Xiao-shu, ZHU Bo, LIU Li-ye(Dept. of pharmacy and Applied Chemistry, Jinlin Institute of Chemical Technology, Jilin 132022, China);Application of chitosan and its derivatives in domain of the medicine[J];Tianjin Chemical Industry;2005-05
6 WANG Yan-bo,REN Yan-hua,ZHENG Ji-wang,ZENG Lan (National Institute on Drug Dependence , Peking University,Beijing 100083,China);Influence of l-tetrahydropalmatine on morphine-induced conditioned place preference[J];Chinese Pharmacological Bulletin;2005-12
7 WANG Yanbo, REN Yanhua **, ZHENG Jiwang (National Institute on Drug Dependence, Peking University, Beijing, 100083);THE EFFECTS OF l-THP ON MORPHINE-INDUCED DISCRIMINATION[J];Chinese Journal of Drug Dependence;2005-01
8 ZHANG Zhong miao 1,2 , ZHENG Xiao xiang, JIANG Bo 1, ZHOU Quan 1 ( 1.Department of Clinical Pharmacy,The Second Affiliated Hospital, College of Medicinal Sciences, Zhejiang University, Hangzhou 310009, China; 2.Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China );Effects of L-tetrahydropalmatine on concentrations of neurotransmitter amino acids in mice with cerebral ischemia[J];China Journal of Chinese Materia Medica;2004-04
9 ZENG Ai-ying,YANG Guangtian,TU En-yuan,et al.Department of Emergency,Tongji Hospital,Tongji Medical College,Huazhong University of Science and Technology,Wuhan 430030,China;Changes of Nitric Oxide Synthase in Lung,Liver and Kidney after Cerebral Ischemia Reperfusion in Rats[J];Chinese Journal of Rehabilitation;2006-06
10 MA Xiao-ya1,WU Dong-mei2,LI Ming3(1.Department of Pharmacy,the Second Affiliated Hospital,School of Medicine,Xi'an Jiaotong University,Xi'an 710004,China;2.Xi'an Children's Hospital,Xi'an 710003,China;3. Department of Histology and Embryology,School of Medicine,Xi'an Jiaotong University,Xi'an 710061,China);The Effects of L-tetrahydropalmatine on the Expression of Apoptosis Protein Fas and FasL in Himppocampal CA_1 after Focal Cerebral Ischemia Reperfusion Injury in Rats[J];Herald of Medicine;2010-09
【Citations】
Chinese Journal Full-text Database 2 Hits
1 LIANG Jian; ZHENG Ping-Xiang; LIANG Jing-Sheng(Dept of Pharmacology, Guangzhou Medical College, Guangzhou 510182);Protective effects of dl-tetrahydropalmatine on focal brain ischemia-reperfusion injury in rats[J];CHINESE PHARMACOLOGICAL BULLETIN;1998-05
2 Ma Jianqun,Mao Huanyuan,Cao Linsheng,et al.Institute of Cardiovascular Disease,Union Hospital of Tongji Medical University,Wuhan 430022;Effects of rotundine on ventricular arrhythmias and endothelin1 concentration in plasma during myocardial ischemiareperfusion[J];CHINESE CRITICAL CARE MEDICINE;1998-01
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 JIANG Chonghui,YANG Guangtian,TANG Yan,et al.Department of Emergency,Zhongshan City Peoples Hospital,Zhong Shan 528400,China;Effects of L-tetrahydropalmatine on neuronal apoptosis during cerebral ischemia/reperfusion in rats[J];Journal of Emergenoy Medicine;2001-06
2 YANG Guangtian,CAO Jianzhong,LIU Shushan,et al.Department of Emergency,Tongji Hospital,Huazhong Science and Technology University,Wuhan 430030,China;The effects of L-Tetrahydropalmatine on the expression of Bcl-2 and Bax in rats after acute global cerebral ischemia and reperfusion[J];Journal of Emergenoy Medicine;2002-06
3 CHEN Qi guo,YANG Guang tian.Department of emergency medicine,Tongji Hospital,Huazhong Science and Technology University,Wuhan 430030,China;The influence of ltetrahydropalmatine on electrolyte contents in brain tissues after cerebral ischemia reperfusion in the rats[J];Journal of Emergency Medicine;2003-03
4 ;Effective Observation on Treatment of Unstable Anginal Pectoris Perfused Rolundine Intravenously[J];Journal of Henan University of Science & Technology(Medical Science);2006-03
5 Sun Chengdong Liu Liqing Lu Yan Wang Shijun (Shandong University of Traditional Chinese Medicine,Jinan 250014);Markers for Experiment of Rat's Local Cerebral Ischemia and Evaluation[J];Shandong Journal of Biomedical Engineering;2002-03
6 YANG Guangtian; WANG Peihua; TANG Yan;JIANG Chonghui; WANG Dixun(Department of Emergency,Department of Internal Medicine,Tongji Hospital, Tongji Medical University, Wuhan 430030Department of Pathophysiology, School of Basic Medical Sciences, Tongji Medic;Effects of L-Tetrahydropalmatine on Energy Metabolism, Endothelin-1 and NO during Acute Cerebral Ischemia-reperfusion of Rats[J];同济医科大学学报(外文版);1999-04
7 YANG Guangtian, JIANG Chonghui , TANG Yan, WANG Peihua. (Department of Emergency, Tongji Hospital, Tongji Medical University, Wuhan 430030) Department of Internal Medicine, Tongji Hospital, Tongji Medical University, Wuhan 430030);Effects of L-Tetrahydropalmatine on Neuron Apoptosis during Acute Cerebral Ischemia-Reperfusion of Rats[J];同济医科大学学报(外文版);2000-02
8 LIU Yan-li1,2,YAN Ling-di1,QI Jia,WU Chun-fu3,GONG Ze-hui1(1.Lab of New Drug Evaluation,Beijing Institute of Pharmacology and Toxicology,Beijing 100850,China;2.College of Pharmacy,Soochow University,Suzhou Jiangsu 215123,China;3.Dept of Pharmacology,Shenyang Pharmaceutical University,Shenyang 110016,China);Studies on effects of ι-tetrahydropalmatine on locomotor sensitivity induced by oxycodone in mice[J];Chinese Pharmacological Bulletin;2007-12
9 JIANG Chong_hui 1,YANG Guang_tian 2,TANG Yan 3,et al. 1Zhongshan City People’s Hospital,Zhongshan 528400,China. 2Department of Emergency,Tongji Hospital,Tongji Medical University,Wuhan 430030,China;Effects of L-Tetrahydropalmatine on energy metabolism eodothelin-1 and NO during acute cerebral ischemia-reperfusion of rats[J];Chinese Journal of Critical Care Medicine;2001-06
10 CHEN Qi-guo YANG Guang-tian.Department of Emergency Medicine,Tongji Hospital,Tongji Medical College,Huazhong Science and Technology University,Wuhan 430030,China;Influence of L-tetrahydropalmatine on cerebral cell apoptosis and calcium content in brain tissues of a cerebral ischemia reperfusion in the rats[J];Chinese Journal of Critical Care Medicine;2002-11
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 YE Hua CHEN Meng ZHONG Lin TAN Tian-wei (College of Life Science and Technology,Beijing University of Chemical Technology,Beijing 100029,China);Effect of fed-batch models on production of hyaluronic acid(HA)[J];Journal of Beijing University of Chemical Technology(Natural Science Edition);2006-01
2 XU Jian-ye,ZHOU Qi, TANG Wei(1.Clinical Examination Center;2.Department of Gynecology;3.Department of Pharmacy,ChongqingTumor Hospital,Chongqing 400030,China);Reversal effect of tetrandrae,rotundini and ligustrazini on human multidrug resistant KBV200 cell line[J];Chongqing Medical Journal;2005-09
3 CHEN Ai Min,HOU Chun Lin,YIN Cheng Hui,WU Hai Shan (Department of Orthopaedic Surgery, Changzheng Hospital, Second Military Medical University, Shanghai 200003,China);Clinical study of chitosan for prevention of knee adhesion[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;2000-02
4 Hou Chunlin;Sheng Zhijian;Lu Jianxi;Cao Meixun;Wu Qingji(Department of Orthopaedic Surgery,Chang zheng Hospital,Second Military Medical University,Shanghai,200003);In Vivo Absorption of Chitin Suture:An Experimental Study[J];ACADEMIC JOURNAL OF SECOND MILITARY MEDICAL UNIVERSITY;1994-05
5 Wu Qingji, Liu Shiying, Zhang Min (College of Material Science & Engineering, China Textile UniTelsity, Shanghai, 200051);Production of Suture from Chitin[J];;1998-05
6 MOU Shan-song 1 , MA An-de 2 , TU Mei 1 , LI Li-hua 1 , ZHOU Chang-ren 11 Institute of Biomedical Engineering, Ji'nan University, Guangzhou 510632, China; 2 Central Laboratory, First Mili-tary Medical University, Guangzhou 510515, China;Preparation of polylactic acid/chitin composite material and its safety evaluation by animal experiments[J];Journal of First Military Medical University;2003-03
7 Pang Zhigong, Wang Baoqi, Wang Congying ( Xi'an Medical University, Xi'an 710061)Huang Hong (Xi'an Pharmaceutical Factory);Distribution and Remainer of Tetrahydropalmatine in Rabbit Viscera[J];Chinese Journal of Analytieal Chemistry;1994-06
8 Yao Zu Liao, Mei Hua Xin, Ming Chun Li, Sheng Su College of Materials Science and Engineering, Huaqiao University, Quanzhou 362021, China;Preparation and characterization O-lauroyl chitosan/poly (L-lactic acid) blend membranes by solution-casting approach[J];中国化学快报(英文版);2007-02
9 PAN Quan Ming, LIU Shi Yong, XIE Jing Wei *, JIANG Ming [WT5”BX](Department of Macromolecular Science and Key Laboratory of Molecular Engineering of Polymers, Fudan University, Shanghai 200433, China);Studies on Complexation-induced Micellization of Block-graft Copolymer SEPG and PS(OH)[J];Chemical Research In Chinese Universities;2000-11
10 TAN Li 1, CHEN Shi-Ming 1 *, YAN Xiao-Min 1, PING Zheng-Hua 2, SHEN Yi-Min 1 (1. Center of Analysis and Measurement; 2. Department of Macromolecular Science, Fudan University, Shanghai 200433, China);A Study of the Chain Motion in STVPh/PEO System by ESR Spin Label[J];Chemical Research In Chinese Universities;2003-06
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 CHEN Li-ming,LI Zhu-lai,WANG Jin(Faculty of Pharmacy,Fujian Medical Univesity,Fujian,350004,China);The Study of Immobilize A-amylase[J];Strait Pharmaceutical Journal;2006-05
2 Zhao Qingmei Lu Quanxian~* Tian Yong~*(College of Chemistry and Environment Engineering,Yangtze University,Hubei Jingzhou 434023;*.Maurer Bridge Accessories Co.Ltd.,Jiangsu Nanjing 211500);Application and Research of Chitin,Chitiosan and their Derivatives in Medicine[J];Chemical Industry Times;2006-05
3 TAN Cheng1 YU Huixin1,2 LIN Xiufeng1 ZHANG Li1 CHEN Bo1 SONG Cuicui2 CAO Guoxian1 1 (Key Laboratory of Nuclear Medicine, Jiangsu Institute of Nuclear Medicine, Ministry of Health, Wuxi 214063, China) 2 (Jiangnan University, Wuxi 214036, China );Radioiodine-labeling of tetrahydropalmatine and its biodistribution in mice[J];Nuclear Techniques;2008-03
4 Wang Huaming Wang Jian (College of Fundamental Subjects,SCUTA,Danzhou,Hainan,571737);Research Progress of Chitosan in Wound Dressing[J];Journal of South China University of Tropical Agriculture;2007-02
5 JIANG Chonghui,HOU De ren,YANG Guangtian,et al.Zhongshan City Peoples Hospital,Zhong shan 528400,China;Effets of L-tetrahydropalmatine on ICAM-1 expression in cerebral microvascular endothelial cells during hypoxia-reoxygenation[J];Journal of Emergenoy Medicine;2003-01
6 ZHOU Haiyan,LI Wei,ZHOU Yifeng,et al.Department of Anesthesiology,The Second Affiliated Hospital,Medical College of Zhejiang University,Hangzhou 310009,China;Effects of ketamine on neuron apoptosis and expression of Caspase-3 and c-fos in gerbils with cerebral ischemia/reperfusion injury[J];Journal of Emergency Medicine;2003-07
7 ZHAO Jian-hao1,2,ZENG Rong1,2,LIU Hong-wei1,TU Mei1,2,LUO Bing-hong1,2,ZHOU Chang-ren1,2(1.Department of Material Science and Engineering,College of Science and Engineering;2.Engineering Research Center of Artificial Organs and Materials,Ministry of Education,Jinan University,Guangzhou 510632,China);Synthesis of N-succinyl-chitosan and the physical-chemical properties[J];Journal of Jinan University(Natural Science Edition);2008-01
8 JIANG Zhen-ju(School of Bioengineering,Xihua University,Chengdu 610039 China),ZHU Liang,et al.JOURNAL OF XIHUA UNIVERSITY.v.27,no.4.PP.88-90,4/2008.(ISSN 1673-159X;In Chinese);Research on the Immobilization of α-amylase with Chitosan Glutaraldehyde[J];Journal of Xihua University(Natural Science Edition);2008-04
9 ZHANG Ai-di,DING De-run (College of Chemistry and Chemical Engineering,Shanghai University of Engineering Science,Shanghai 201620,China);Application Process of Chitosan-based Biomedical Materials[J];Journal of Shanghai University of Engineering Science;2009-01
10 ZHAO Hong-bin1,2,ZHANG Xi-zheng1,LI Rui-xin1,XIE Hong-wei3,CHEN Xu-yi1(1.Institute of Medical Equipment,Academy of Military Medical Sciences,Tianjin 300161,China;2.Generation Hospital Lanzhou Command,Lanzhou 730050,Gansu,China;3.Medical College of the Chinese People's Armed Police Forces,Tianjin 300162,China);Experimental study on bone marrow mesenchymal stem cells cultured with eggshell membrane scaffold[J];Biomedical Engineering and Clinical Medicine;2006-04
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Cheng Longxian Map Huanyuan Dai Shuiping et al (Institute of Cardiovascular Disease,Tongji Medical University,Wuhan);Effects of 1-tetrabydropalmatine on calcium channel currents in isolated guinea-pig ventricular myocytes[J];Journal of Clinical Cardiology;1995-03
2 Zhao Dongke, et al (Department of Pharmacology);EFFECTS OF DL-TETRAHYDROPALMATINE ON ACTION POTENTIALS AND CONTRACTILITIES OF GIUNEA PIG PAPILLARY MUSCLES AND ITS LOCAL ANESTHETIC ACTION[J];Journal of Xi'an Jiaotong University(Medical Sciences);1986-03
3 Huang Yali; Lu Tong;Jiang Wenpin.(First Affiliated Hospital, Suzhou Medical College, Suzhou 215006);The action and mechanism of trigger activity of endothelin-1 on ventricular myocytes of guinea pig[J];CHINESE JOURNAL OF CARDIOLOGY;1995-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved