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《Journal of Jilin University(Science Edition)》 2010-04
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Fingerprints with Hierarchical Cluster Analysis for Ease Pill by Gas Chromatography

LIANG Yue,WEI Shi-gang,RU Xin,YU Ai-min,SHI Yu-hua(College of Chemistry,Jilin University,Changchun 130012,China)  
The volatile components in Ease Pill from 10 manufacturers were extracted by hydrodistillation and detected by gas chromatography(GC).GC fingerprints were established and analyzed by the method of hierarchical cluster analysis,by which the discrimination of the samples from different manufacturers was achieved.The optimized extraction parameters were distilling 11 h,a ratio of drug to water of 1:15,soaking 10 h and n-octadecane was chosen as the internal standard substance.The results of hierarchical cluster analysis show that there are discriminations among gas chromatography common peaks areas of Ease Pill from different manufacturers,which indicates the standard in medicine production should be improved.
【Fund】: 吉林大学科学前沿与交叉学科创新项目(批准号:200903131)
【CateGory Index】: R286.0
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