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《Journal of Medical Postgraduates》 2009-11
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Experimental study on implanted microwave ablation in porcine lungs in vitro

LI Xin1,ZHANG Hong1,SHENG Lin2,CHI Bao-qi2,LU Tong3,HANG Zhi-yu3,DONG Bao-wei3(1.Department of Ultrasound,General Hospital of the Chinese Armed Police Force,Beijing 100039,China;2.Department of Ultrasound,The Second Affiliated Hospital of Tsinghua University,Beijing 100049,China;3.Department of Ultrasound,Chinese PLA General Hospital,Beijing 100853,China)  
Objective: Microwave ablation has a satisfactory clinical efficacy for hepatic carcinoma.The purpose of this study is to investigate the regularity of microwave ablation-induced temperature rising in porcine lungs in vitro,which is hoped to provide an experimental basis for the treatment of pulmonary carcinoma.Methods: The rigid microwave antenna with internally cooled water was directly implanted into the porcine lungs in vitro,with a microwave frequency of 2450 MHz.Different irradiation power outputs were used for 15 minutes and the temperature curves of the selected spots were simultaneously recorded by the iron-constantan couple temperature-measuring system.Results: Fifty-six experiments were accomplished,with the temperature curves of 224 spots recorded,4 spots(r=5,10,15 and 20 mm) in each experiment.The temperature at each spot reached the peak in a short time,then became steady,and began to fall rapidly when the microwave ablation was stopped.The changes of the curves were more obvious when the spot was nearer to the original point and/or when the power was higher.Conclusion: The characteristics of the temperature curve of the lungs in vitro are different from those of the liver.
【CateGory Index】: R73-3
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