Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Medical Postgraduates》 2014-06
Add to Favorite Get Latest Update

The correlation research progress between leptin and senile osteoporosis

SUN Xi-feng;LIANG Jie;The Cadres Comprehensive Medical,First Affiliated Hospital of Xinjiang Medical University;  
Osteoporosis is a kind of systemic metabolic bone diseases,characterized by bone loss,bone subtle structural damage.Leptin is a peptide hormone which secreted by fat cells,that has both positive and negative effects to the bone,and plays a role of regulating on bone metabolism.In vitro,Leptin can regulate proliferation of osteoblast and inhibit reabsorption of osteoblasts depend on osteoclast.In vivo,Leptin can inhibit the synthesis of serotonin in the brain stem and increase the sympathetic nerve signals output by the hypothalamus to the bone,it mainly has a negative effect.But clinical trials about the correlation between Leptin and senile osteoporosis,the role of Leptin in the central nervous system and peripheral tissue problems are still unclear.In this paper,we will make a comprehensive overview about the latest research progress in the correlation between leptin and senile osteoporosis.
【CateGory Index】: R580
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 2 Hits
1 SHAO Jia-qing,CHEN Ji-hai reviewing,WANG Jian checking (Department of Endocrinology,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing 210002,Jiangsu,China);Suppressors of cytokine signaling proteins and diabetes mellitus[J];Journal of Medical Postgraduates;2010-05
2 WANG Gui-hua reviewing,ZHAO Jian-ning checking (Department of Orthopedics,School of Medicine,Nanjing University/Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing 210002,Jiangsu,China);Influence factors and detection of bone quality[J];Journal of Medical Postgraduates;2011-10
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 LIU Yong-liang,YE Gang,FANG Zhen-qiang(Department of Urinary Surgery,Renal Diseases Research Center of PLA,Xinqiao Hospital,Third Military Medical University,Chongqing 400037,China);Experimental study of primary culture and multi-directional differentiation of rabbit bone marrow derived mesenchymal stem cells in vitro[J];Chongqing Medicine;2008-08
2 QI Zhen-xi1,LI Shu-qiang2,YU Tao2(1.Institute of Medicine on Osteopathis,Fujian Academy of Integrative Medicine,Fuzhou,Fujian 350108,China;2.Orthopaedic and Traumatology Department,FUTCM,Fuzhou,Fujian 350108,China);Effect of Ground Beetle on Expression of PPARγmRNA and aP2mRNA in Steroid-induced Bone Marrow Mesenchymal Stem Cells[J];Journal of Fujian University of Traditional Chinese Medicine;2010-04
3 TANG Feng-ming,WANG Jing-gui,ZHAO Dong,et al. Department of Orthopedics,the Affiliated Hospital of Armed Police Medical College,Tianjing 300162,China;Mid-term analysis of glucocorticoid induced femoral head necrosis and osteoporosis in 49 patients[J];Chinese Journal of Bone and Joint Injury;2012-02
4 CHEN Yan-ping~(1*),XUE Yan~2,HUANG Ke-qin~3,et al 1.Orthopaedics Research Institute of China Academy of Chinese Medical Science,Beijing 100700; 2.Institute of Orthopaedics & Traumatology,Beijing Jishuitan Hospital,Beijing 100035; 3.Beijing Huang Cheng Osteonecrosis Hospital,Beijing 102200; 4.The Nantional Engineering Reseach Center for Beijing Biochip Technology,Beijing 102206,China;Gene expression profiling and pathways related fat metabolisim in rats with glucocorticoid-induced avascular necrosis of the femoral head[J];Chinese Journal of Osteoporosis and Bone Mineral Research;2010-03
5 XUAN Jing-jing,ZHANG Yuan-chao (Department of Rheumatology and Immunology,Provincial Hospital Affiliated to Shandong University,Ji'nan 250021,China);Glucocorticoids and femoral head osteonecrosis in systemic lupus erythematosus patients[J];World Clinical Drugs;2011-01
6 Massimo Marenzana;Timothy R. Arnett;Department of Bioengineering, Imperial College London and Kennedy Institute of Rheumatology, University of Oxford,UK;Department of Cell and Developmental Biology, University College London,UK;;The Key Role of the Blood Supply to Bone[J];骨研究(英文版);2013-03
7 WANG Chun-yu;LONG Feng-yun;CHEN Xiang;YU Xi-jie;Laboratory of Endocrinology and Metabolism,West China Hospital,Sichuan University;Sichuan Leshan Qianwei Maternal and Child Health Hospital;;The osteocalcin-mediated bone endocrine system[J];Chinese Journal of Osteoporosis and Bone Mineral Research;2013-03
8 LI Jing-bao;LIN Xiao;ZHOU Hong;Bone Research Program,ANZAC Research Institute,The University of Sydney;Key Laboratory for Space Biosciences and Biotechnology,Institute of Special Environmental Biophysics,School of Life Sciences,Northwestern Polytechnical University;;Glucocorticoids and bone[J];Chinese Journal of Osteoporosis and Bone Mineral Research;2013-04
9 CHEN Hui-ying;YUAN Hui-shu;Deparment of Radiology,Peking University Third Hospital;;Marrow fat quantifi cation by magnetic resonance technology:the aplication and prospect in bone diseases[J];Chinese Journal of Magnetic Resonance Imaging;2014-02
10 WANG Chengyong;LIN Hai;WANG Jin;WEI Hongying;ZHANG Deqing;LU Meng;CHEN Weihui;Department of Oral and Maxillofacial Surgery,Oral and Maxillofacial Deformity Prevention Laboratory,Fujian Medical University Union Hospital;Department of Dental Implant,Xiamen Stomatological Hospital;Department of Dental,Pucheng Hospital;Department of Dental,The Second Hospital of Longyan;;Effect of Sympathetic Denervation on Bone Formation and Remodeling[J];Journal of Fujian Medical University;2014-01
【Secondary Citations】
Chinese Journal Full-text Database 5 Hits
1 XIE Chao-yong reviewing,ZHANG Zhi-hong checking(Centre of Stomatology,Anhui Provincial Hospital,Hefei 230021,Anhui,China);The evaluation of the quality of jaws after dental implants and its significance[J];Journal of Medical Postgraduates;2007-08
2 PENG Xiao-ren,ZOU Da-jin(Department of Endocrinology,Changhai Hospital,the Second Military Medical University,Shanghai 200433,China);Expression of FOXC2 in adipose tissues and its correlation with obesity and insulin resistance[J];Journal of Medical Postgraduates;2008-06
3 ZHAO Ming reviewing,LIU Zhi-min checking(Department of Endocrinology,Nanjing General Hospital of Nanjing Military Command,PLA,Nanjing 210002,Jiangsu,China);Subcutaneous insulin resistance: a new type of insulin resistance[J];Journal of Medical Postgraduates;2008-10
4 XIA Xin-yi,CUI Ying-xia,YANG Bin,WANG Hao-yang,LU Hong-yong,YAO Bing,LI Xiao-jun,HUANG Yu-feng(Department of Clinical Experiment Medicine,Institute of Clinical Laboratory Medicine,Nanjing University School of Medicine,Nanjing General Hospital of Nanjing Military Commond,PLA,Nanjing 210002,Jiangsu,China);A novel RNA-splicing mutation in COL1A1 gene causing osteogenesis imperfecta typeⅠin a Chinese family[J];Journal of Medical Postgraduates;2009-03
5 WEI Yanan, MIAO Yide, LIU Zhonghou, et al. The Department of Geratology, Peking University People's Hospital, Beijing 100044, China;Clinical progress in biochemical markers for bone metabolism—Review in biochemical markers for bone metabolism in different countries and regions in premenopausal and postmenopausal women[J];Chinese Journal of Osteoporosis;2007-07
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved