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《Jilin Medical Journal》 2002-05
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Changes of the Weight and Coefficient of Sexual Gland and the Level of Sexual Hormone in Adult Diabetic rat

LIU Su-huan,LI Zhe,ZUO Wen-jing,et al(Deptarment of Cell Biology,School of Basic Medical Sciences,Jilin University,Changchun 130021,China)  
Objective To investigate the influences of diabetes on the level of sexual hormone and the impairments on the sexual gland in adult rat.Method To detect the level of sexual hormone using radio-immune kit,weigh the sexual gland and calculate the coefficient of sexual gland.Results The weight of testis,epididymis,prostate and seminal resicle of the diabetic and insulin replacement group is significantly lower than that of the control group,the coefficient of prostate and seminal resicle of diabetic group is lower than that of the control group,the serum testosterone level of diabetic and insulin replacement group is significantly lower than that of the control group.Conclusion The sexual glands of the adult rat were impaired seriously by diabetes,also the ability of the testis to secrete testosterone was impaired.
【Key Words】: Adult Diabetes Reproductive gland Sexual hormone
【Fund】: 国家自然科学基金资助课题 (39870 31 3)
【CateGory Index】: R587.1
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【References】
Chinese Journal Full-text Database 1 Hits
1 Hong Jun WANG 1 , Jia Ying ZHANG 2 , Su Huan LIU 1 , Hui ZHAO 1 , Zhong Shan WANG 1 (1 Department of Cell Biology, 2 the Second General Laboratory, School of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, China);Changes of 5 Alpha-reductase Type Ⅱ Activity in Sexual Gland of Diabetic Male Rats[J];Acto andrologica Sinica;2003-02
【Citations】
Chinese Journal Full-text Database 1 Hits
1 Wang Zhong Shan, et al Norman Bethune University of Medical Sciences(Changchun 130021);Observation on sexual organ weight and behavior in pubertal rats with diabetes[J];;1996-02
【Co-citations】
Chinese Journal Full-text Database 5 Hits
1 ZOU Dong hui,WANG Zhong shan,ZHAO hui,Xu Zong ge (Department of Cell Biology, School of Basic Medical Sciences, Jilin University,Changchun130021 China);Dynamic analysis of sexual organ weight and serum levels of glucose, glycosylprotein, testosterone in male rats with short-term diabetes[J];Journal of Norman Bethune University of Medical Science;2001-05
2 Hong Jun WANG 1 , Jia Ying ZHANG 2 , Su Huan LIU 1 , Hui ZHAO 1 , Zhong Shan WANG 1 (1 Department of Cell Biology, 2 the Second General Laboratory, School of Basic Medical Sciences, Jilin University, Changchun, Jilin 130021, China);Changes of 5 Alpha-reductase Type Ⅱ Activity in Sexual Gland of Diabetic Male Rats[J];Acto andrologica Sinica;2003-02
3 Liu Suhuan, Zhao Hui, Xin Jili, Zou Donghui, Wang Zhongshan Dept. of Cell Biology, School of Basic Medical Sciences , Jilin University ( Changchun 130021) Liu Yijie Dept. of Radioactive Therapy, the General Hospital of the First Automobile Work;Changes of gene expression and the level of androgen receptor in reproductive glands of diabetic pubertal rat[J];Chinese Journal of Andrology;2002-05
4 Wang Zhongshan,Zhao hui,Zou Donghui,Xu Zongge,Xin Jili Department of Cell Biology,School of Basic Medical Sciences,Jilin University (Changchun 130021);A research on oxygen free radicals and antioxidant enzymes of testes in the male rats with short-term diabetes[J];Chinese Journal of Andrology;2003-02
5 HU Shan-shan,SHEN Xiu-ying,XU Xiao-lu,CHEN Yong-yi(Institute of ecology,Zhejiang Normal University,Jinhua 321004,China);Effect of subchronic samarium exposure on sexual behavior of mice[J];Journal of Toxicology;2008-03
【Co-references】
Chinese Journal Full-text Database 2 Hits
1 Yu-Gui CUI1, Gui-Yuan ZHANG2 (1. Department of Endocrinology, the First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China; 2. National Research Institute of Family Planning, Beijing 100081, China);Steroid 5α-Reductase Activity, Androgen Level and Its Receptor in the Target Tissues of Male Fetuses[J];Acto andrologica Sinica;2001-04
2 Wang Zhong Shan, et al Norman Bethune University of Medical Sciences(Changchun 130021);Observation on sexual organ weight and behavior in pubertal rats with diabetes[J];;1996-02
【Secondary References】
Chinese Journal Full-text Database 5 Hits
1 LI Xiao mei,LU Yan juan,LI Xiao lin * (Experimental Center of Biochemistry and Molecular Biology,School of Basic Medical Sciences, Jilin University, Changchun 130021,China);Changes of POD activities in the key organs in adult rats with diabetes[J];Journal of Jilin University of (Medicine Edition);2004-01
2 LU Yan juan, LI Xiao lin , LI Xiao mei (Experimental Center of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Jilin University, Changchun 130021,China);Changes of levels of GSH-Px, GSH,and GR in important organs and tissues of adult diabetic rats[J];Journal of Jilin University of (Medicine Edition);2004-03
3 YAN Dong-mei TU Ling-lan LI Wen-jun (Zhejiang Academy of Medical Sciences,Hangzhou 310013,China);