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《Jilin Medical Journal》 2011-28
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Influence of total flavonoids in propolis on biochemical indexes in myocardial ischemia dogs with ligation of coronary artery

SUN Yan,LV Ruo-gu,QUE Xiao-dong,et al(The Jilin Provincial People's Hospital,Changchun 130021,China)  
Objective To observe the influence of total flavonoids in propolis on several serum biochemical indexes in myocardial ischemia dogs with ligation of coronary artery.Method The model of acute myocardial ischemia was established by ligating the left anterior descending(LAD) artery of anesthetic dogs,and the effects of total flavonoids in propolis on creatine kinase(CK),lactic dehydrogenase(LDH),free fatty acid(FFA),lipid peroxide(LPO),superoxide dismutase(SOD) and glutathione peroxide(GSH-Px) were observed.Results The total flavonoids in propolis could evidently lower the activity of CK and LDH,reduce FFA and LPO levels,as well as increase the activity of SOD and GSH-Px in serum.Conclusion Total flavonoids in propolis has protective effect on the damage of lipid peroxidation caused by experimental myocardial ischemia.
【CateGory Index】: R285.5
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