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《Journal of Jinan University(Natural Science & Medicine Edition)》 2003-06
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Ultrastucture of endometrium from rat endometriosis and the effect of Danazol on its ultrastructure

MA Bao-feng~1,ZHENG Hui~1,WANG Zi-neng~2,HE Si-chun~1, BAI Zhi-quan~1,WANG Yue-chun~1 (1. Dept. of Physiology, Medical College, Jinan University, Guangzhou 510632, China; 2. Dept. of Gynecology & Obstetrics, First Affiliated Hospital, Jinan University, Guangzhou 510630, China)  
Aim: To explore the ultrastructural change of eutopic and ectopic endometrium from rat uterus. Methods: According to Jones's method, rat animal model with endometriosis was established. The endometrial and endometriotic tissue was acquired for transmission election microscopic examination at six weeks after modeling. Results: In comparison with the control group , ectopic endometrium has discontinuous basement membrane and vacuolated mitochondrion; necrotic cell、 vacuolated mitochondrion、 expanded rough endoplasmic reticulum and autophagosome in ectopic endometrium were commonly seen after Danazol treatment. Conclusion: Ultrastructure of the endometrium was changed after transplantation; necrotic cell and altered organelles in ectopic endometrium are commonly seen after Danazol treatment.
【CateGory Index】: R711.71
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【References】
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1 Zhao Fang1, Chu Yuxia2, Feng Yinman3(1. Institute of Reproductive Medicine, Luoyang Heath Care Center of Maternity and Children, Luoyang, Hennan, 471000;2. Department of Gynecology and Obstetrics, Henan Hospital of TCM, Zhengzhou, Henan, 450002;3. Zhengzhou Board of Health, Zhengzhou, Henan, 450003);Influence of Daihuang Zhechong Pellet on Immunologic Function of Fxpriental Endometriosis Rats[J];Henan Traditional Chinese Medicine;2008-10
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