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《Journal of Jinan University(Natural Science & Medicine Edition)》 2009-05
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Chemical Constituents of Elephantopus scaber

HUANG Ting1,2,WU Xia1,2,WANG Ying1,2,YE Wen-cai1,2,LI Yao-lan1,2(1.Institute of Traditional Chinese Medicine & Natural Products,Jinan University; 2.Guangdong Province Key Laboratory of Pharmacodynamic Constituents of TCM and New Drugs Research,Jinan University,Guangzhou 510632,China)  
The chemical constituents of Elephantopus scaber was separeted and purified by various chromatogramphic technologies,including silica gel,Sephadex LH-20,and ODS columns.Nine compounds were obtained from the EtOAc fraction of ethnolic extract of the herb.On the basis of pectroscopic analyses and chemical reactions,the structures of the afforded compounds were identified as physcion(1),isovanillic acid(2),courmaric acid(3),p-hydroxybenzoic acid(4),ferulic acid(5),3-methoxy-4-hydroxyl-cinnamic aldehyde(6),stigmasterol-3-O-β-D-glucoside(7),stigmasterol(8),indazole(9).Compounds 1,2,4,5,6,9 were isolated from this herb for the first time,and compounds 9 is a new natural product.
【Fund】: 国家自然科学基金项目(30840099);; 教育部重点项目(106155);; 广东省自然科学基金项目(9151064101000027)
【CateGory Index】: R284.1
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