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《Journal of Jinan University(Natural Science & Medicine Edition)》 2013-02
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Follow-up for 22 cases of lung cancer after radiofrequency ablation(RFA) by CT

ZHANG Hongdan1,CUI Yanhai2,ZHAO Zhenjun2(1.Department of Radiotherapy;2.Department of Radiology,Guangdong Academy of Medical Sciences & Guangdong General Hospital,Guangzhou 510080,China)  
Aim:The aim of this study was to evaluate the security and therapeutic value of CT guided radiofrequency ablation(RFA) in the treatment of lung cancer,and to find the CT features after RFA in follow-up.Methods: Twenty-two patients with pulmonary neoplasms were underwent CT guided RFA therapy.All lesions were adenocarcinoma,which were composed of 16 cases of primary lesion and 6 cases of secondary lesion.Tumor sizes were 7 mm~37 mm(median was 23mm).The therapeutic effects and complications after RFA were accessed by spiral CT scanning,including the changes of the size and blood supply.Results: All cases did not occur severe complications.The time of CT follow-up was from 14 days to 4 years(median was 10 months).There were 18 cases were followed up over 3 months,and 2 lesions recurred among the 18 cases.The size of lesion after RFA decreased gradually with time prolong,and no enhancement was found in ablation focus,and the cavity appeared in some cases.The size increased and irregular or nodule enhancement were showed when tumor recurred.Three month was regarded as a suitable time to judge tumor activity after RFA.Conclusion:CT guided RFA is a safe,effective and minimally invasive procedure for lung cancer.It can act as an alternative option to treat inoperable lung cancer and decrease tumor local burden.
【Fund】: 广东省医学科研基金项目(A2004038)
【CateGory Index】: R734.2
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