Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《JOUNAL OF JINNING MEDICAL COLLEGE》 1999-04
Add to Favorite Get Latest Update

INFLUENCE OF RADIX SALVIAE MILTIORRBIZAE ON PHENOTYPICAL EXPRESSION OF FIBROBLASTS

Li Jingshan, Ma Jing, Zhu Yaping,et al. (Jining Medical College)  
Objective In order to elucidate the effects of Radix Salviae Miltiorrbizae (RSM)on the phenotypical expression of fibroblasts cultured in vitro.Methods The fibroblasts were isolated and purified from human skin, and were cultured in the presence of various concentrations of RSM or cytokins associated with various concentrations of RSM. The characteristics of the fibroblastic morphology was observed with scanning electron microscope (SEM), and the nodules formed in the fibroblasts culture were analyzed using an eletron microscope fitted with a Kevex energy dispersive X-Ray analysis system.Result When the cualture was treated with 0.2% RSM,the fibroblasts could change from spindle-shape to squamous-shape. RSM was capable of inducing cell proliferation as well as stimulating secretion of collagen. The formation of mineralized nodules was observed in the fibroblast cultures with TNF-α and BMP 2.Conclusion RSM significantly enhanced the formation of these nodules, which showed the presence of Ca and P by using X-Ray microanalalysis. We may concluded the RSM can promote osteogenesis by the fibroblasts cultured in vitro.
【Fund】: 山东省自然科学青年基金!(Q96C01120)
【CateGory Index】: R285
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【References】
Chinese Journal Full-text Database 2 Hits
1 Ming Zhi-jun,Cao Li(School of Pharmacy,Suzhou Univeristy,Jiangsu Suzhou 215123);Effect of Extract of Paeonia Lactiflora and Salvia Miltiorrhiza on Antagonizing Liver Fibrosis Induced by Carbon Tetrachloride in Rats[J];Suzhou University Journal of Medical Science;2005-06
2 HE Xu-feng,SHEN Qiang.Department of Orthopaedics and Traumatology,Yueyang Hospital Affiliated to Shanghai University of TCM,Shanghai 200437,China;Progress of internal research of promotion of Salvia miltiorrhiza Bge on fracture healing[J];China Journal of Orthopaedics and Traumatology;2007-06
【Citations】
Chinese Journal Full-text Database 3 Hits
1 /XuRonghui,et al.(Shanghai Instittite of Traumatolo-gy and Orthopaedics 200025);Effect of Radix Salviae Miltiorhizae on Growth of Isolated Cells from Embryonic ChickenFrontal Bone Cultured in Vitro I.The Develop-ment and Maturation of Osteoblast -like Cells[J];CHINESE JOURNAL OF ORTHOPAEDICS;1994-03
2 Chai Ben-fu;Tang Xue-ming; XuRong-hui.( Shanghai Institute of Traumatolohy andOrthopaedics,Shanghai Second Medical University,Shanghai 200025. );TOsteogenic potential of rabbit dermal fibroblasts cul-tured in vitro: a histochemical and scanning electronmicroscopic study[J];Chiese Journal of Surgery;1994-07
3 Deng Lianfu, Tang Xueming, Chai Benfu et al. The Laboratory of Cell Biology. Second Medical University of Shanghai, Shanghai, P.R. China 200025;REGULATORY FACTORS OF OSTEOGENIC PHENOTYPICAL EXPERESSION BY FIBROBLASTS IN VITRO[J];CHINESE JOURNAL OF REPARATIVE AND RECONSTRUCTIVE SURGERY;1998-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Su Youxin,Zheng Liangpu,Qian Songtao,et al Fujian College of TCM,Fuzhou(350003);Effect of Qianggubao on Bone Density and Biochemical Quota of Diabetic Osteoporosis(DOP)Patients[J];Journal of Zhejiang College of Tcm;2002-04
2 QIAN Yi-ming, CHU Tong-wei, LI Jian-ming, LIU Yu-gang (Department of Orthopaedics, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China);Expressions of VEGF and TNF-α in interspinous ligament of patients with ankylosing spondylitis in active stage[J];Acta Academiae Medicinae Militaris Tertiae;2008-15
3 Gao Gende,Liu Yaosheng.Affiliated Hospital,Zhejiang College of Traditional Chinese Medicine,Hangzhou,310009.;OSTEOGENIC ROLE PLAYED BY FIBROBLASTS OF THE SUPRA INTERSPINOUS LIGAMENT OF ANKYLOSING SPONDYLITIS IN VITRO[J];CHINESE JOURNAL OF RHEUMATOLOGY;1998-04
4 SU You\|xin\+1,QIAN Song\|tao\+1,DONG Zhong\+2,et al\;(1.Dept.of Orthopaedics & Traumatology,FCTCM,Fuzhou,Fujian 350003,China; 2.Second Affiliated People's Hospital,FCTCM,Fuzhou,Fujian 350003,China);Clinical Observation on QIANGUBAO for Treating 40 Cases of Diabetic Osteoporosis[J];Journal of Fujian College of Traditional Chinese Medicine;2001-03
5 ZHANG Shaojun *, PENG Fengmei, ZHANG Jincai, et al. * West China College of Stomatology, Sichuan University, Chengdu 610041;The Effects of Recombinant Human Bone Morphogenetic Protein-2 on the Mineralization Capability of Human Gingival Fibroblasts in Vitro.[J];Journal of Dental Prevention and Treatment;2004-01
6 SHI Jian 1) , LIN Yue-qiu 2) , WANG Li 3) (1)Dept. of Postgraduate,The Third Military Medical College,Chongching 400038;2)Dept. of Orthopedics, Kunming General Hospital of PLA, Kunming 650032;3)Dept. of Pathology,Kunming General Hospital of PLA,Kunming 650032)$$$$;The Study of Dose-Effect Relationship on Human Fibroblasts Strain KMB-17 Trans Fected with Bone Morphogenetic Protein-2 Gene[J];Academic Journal of Kunming Medical College;2002-04
7 KONG Hang1,ZHANG Yan2,JIANG Xin-quan3,PAN Ke-feng2(1.School of Materials Science and Engineering,Tongji University,Shanghai 200092;2.Department of Oral and Maxillofacial Surgery,Hospital of Stomatology,Tongji University,Shanghai 200072;3.Laboratory of Oral Bioengineering,the Ninth People's Hospital,Shanghai Jiaotong University,Shanghai 200011,China);Differentiation and Proliferation of Rabbit Bone Marrow Stromal Cells into Osteoblasts in Vitro[J];Journal of Oral and Maxillofacial Surgery;2006-01
8 WANG Xing guo,WEN Shu zheng,CHONG Xiao xia,REN Xiao dong (Second Affiliated Hospital, Inner Mongolia Medical College,Hohhot 010030 China );EXPERIMENTAL STUDY OF PEDICLE SKIN FLAP TRANSPLANTED INTO THE ARTICULATION[J];ACTA ACADEMIAE MEDICINAE NEIMONGOL;2000-02
9 XUE Liang Zhejiang Sports Science Institution,Zhejiang Hangzhou,310004,China.;The Progress of Research on the Application of Bone Mophorgenetic Protein in Sports Injury[J];Sichuan Sports Science;2006-03
10 NIE Cai-xian1,YANG Cheng1,HE Cheng-qi2.1.Sichuan Provincial People's Hospital,Chengdu,Sichuan 610072;2.West China Hospital,Sichuan University,Chengdu,Sichuan 610041,China;The effect of gutongningcaiji on the histology of the femur with osteoporosis in ovariectomized rat[J];Sichuan Medical Journal;2008-10
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 Yuan Shu-Lan, Wang Xiu-Jie, Wei Yu-Quan Key Laboratory of Biotherapy of Human Diseases,Ministry of Education,West China Hospital, Sichuan University, Chengdu,Sichuan,610041, P.R.China;Anticancer Effect of Tanshinone and Its Mechanisms[J];Chinese Journal of Cancer;2003-12
2 WT5”BZ] LIU Xiao yong et al.Faculty of Stomatology,Capital University of Medical Science,Beijing 100050 [WT5”HZ];EFFECTS OF BASIC FIBROBLAST GROWTH FACTOR ON THE PROLIFERATION AND ALKALINE PHOSPHATASE EXPRESSION OF HUMAN PERIODONTAL LIGAMENT CELLS.[J];Beijing Journal of Stomatology;2001-02
3 Chen Ping;Han Benli;Li Kun;Duan Henchun (Department of Hepatobiliary Surgery, Southwest Hospital, Third Military Medical University,Chongqing, 400038);The effects of activated Kupffer cells on liver cell regeneration in cirrhotic rats[J];ACTA ACADEMIAE MEDICINE MILITARIS TERTIAE;1998-04
4 Gao Gende,Liu Yaosheng.Affiliated Hospital,Zhejiang College of Traditional Chinese Medicine,Hangzhou,310009.;OSTEOGENIC ROLE PLAYED BY FIBROBLASTS OF THE SUPRA INTERSPINOUS LIGAMENT OF ANKYLOSING SPONDYLITIS IN VITRO[J];CHINESE JOURNAL OF RHEUMATOLOGY;1998-04
5 ;新型义齿稳固剂的急性毒性实验[J];Journal of Dental Prevention and Treatment;2003-02
6 Zhang Zhiwei, Wu Zaide, Chen Xiaoping (Department of Surgery, Tongji Hospital Tongji Medical University, Wuhan 430030 China);THE INFLUENCE OF LABIATAE ON ENZYMHISTOCHEMI ISCHEMIC LIVER REMNANT IN RATS[J];CHINESE JOURNAL OF HISTOCHEMISTRY AND CYTOCHEMISTRY;1998-03
7 Chen Liming, Zeng Tairan, Tian Maoneng Department of Oral Medicine, Guiyang Stomatological Hospital, Guiyang 550002;Clinical studies of guided tissue regeneration on periodontal disease[J];Guizhon Medical Journal;2002-12
8 Ji Jianxin, Liao Weijiao, Qiu Zhihui, et al. Department of Stomatology, the First Affiliated Hospital, Guangzhou Medical College, Guangzhou 510120, China;Effect of transforming growth factor-α,β and basic fibroblast growth factor on the fibronectin and alkaline phosphatase activity in human periodontal ligament cells in vitro[J];Guangzhou Medical Journal;2005-02
9 Shen Jing 1, Zhu Haiqing 1, Zhao Yi 2, Pan Liquan 2 (1.the Affiliated Brain Diseases Hospital of Nanjing Medical University. Nanjing, Jiangsu, 210029; 2. Nanjing University of TCM. Nanjing, Jiangsu, 210029);Pathologic Observation of TGF-β Reaction of Gastric Wound Tissues Treated by Danshen Yaomo[J];Henan Traditional Chinese Medicine;2004-03
10 Wang Qintao, Wu Zhifen, Dong Guangying, et al Department of Periodontology, College of Stomatology, the Fourth Military Medical University;Effects of BMP on Periodontal Ligament Cell's Cell Cycling and DNA Synthesis: a Flow Cytometry (FCM) Analysis[J];WEST CHINA JOURNAL FOF STOMATOLOGY;1999-03
【Secondary References】
Chinese Journal Full-text Database 2 Hits
1 HUO Liwei,LIN Hanhua;CLINICAL OBSERVATION OF 36 CASES DELAYED HEALING FRACTURES TREATED WITH DECOCTION OF RADIX ANGELICAE PUBESCENTIS AND HERB TAXILLI[J];Modern Hospital;2009-06
2 HUO Liwei,LIN Hanhua;CLINICAL OBSERVATION OF MODIFIED DUHUO JISHENG DECOCTION TREATING IN 36 CASES OF FRACTURE DELAYED UNION[J];Modern Hospital;2009-07
【Secondary Citations】
Chinese Journal Full-text Database 1 Hits
1 Xu Ronghai, Chai Benfu Shanghai Institute of Traumatology and Orthopedics, Shanghai;Effect of Radix Salviae Miltiorrhizae on Fracture Healing of Rabbit Radius[J];Acta Universitatis Medicinalis Secondae Shanghai;1988-04
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved