Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Journal of Jining Medical College》 2008-01
Add to Favorite Get Latest Update

Effects of Rosiglitazone and Metformin on Insulin Resistance and Carotid Intima-Media Thickness in Patients with Type 2 Diabetes Mellitus

LIU Yanqing,WANG Xuguang(Shangdong Academy of Medical Sciences)  
Objective To analyze the relationship between insulin resistance,FINc and carotid intima-media thickness in type 2 diabetes mellitus,and to observe the therapetic effects of rosiglitazone and metformin,and investigate the potential cardiovascular protective effect of thiazolidinediones and biguanides and the early atherogenic risk factors in patients with type 2 diabetes mellitus.Methods 141 subjects with type 2 diabetes mellitus were selected and divided randomly into three groups: rosiglitazone,metformin and alliance groups,then the three groups were given different medicine.For 12 weeks,then compared the changes of above indexes with treatment.Results After treatment FINs and IRI of alliance group were showed more a decrease than rosiglitazone group(P0.05) and metformin group(P0.000).three groups before and after treatment the level of CIMT were not showed a significantly decrease(P0.05).Conclusion Resiglitazone and metformin may reduce more fasting insulin and insulin resistance than dependent each one,but three medicine have no influence on CIMT in short time.
【CateGory Index】: R587.1
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 1 Hits
1 ;Influence of rosiglitazone on serum resistin and blood pressure in rats with insulin resistance[J];Academic Journal of Second Military Medical University;2005-12
Chinese Journal Full-text Database 10 Hits
1 LI Xiaoling,ZHU Lüyun.Department of Endocrinology,the Bethune International Peace Hospital,Shijiazhuang 050082,Hebei;Relationship of albumin excretiontate and carotid intima-media thickness in newly diagnosed type 2 diabetic patients[J];Clinical Medicine;2006-10
2 Su Yana,Shi YaxiongThe Affiliated Second Hospital,Fujian Medical University,Quanzhou,362000,China;The Relationship between Microalbuminuria and Carotid Intima-media Thickness in Type 2 Diabetic Patients[J];Journal of Fujian Medical University;2006-05
3 YANG Teng-shun,SHAO Hui-ge,OUYANG Jun (The First Hospital of Changsha,Changsha,Hunan 410005,China);Modulation Effect on Dislipidemia and Atherosclerosis by Atorvastatin in Newly Diagnosed Type 2 Diabetes Patients[J];Journal of Hunan Normal University(Medical Sciences);2008-01
4 SUN Ming-Xiao1,2,GUO Han-Bang3,JIANG Lei2,DONG Jun3,WANG Shu3,and CHEN Wen-Xiang3 (1.Graduate School,Bejing Sports University;2.Department of Endocrinology and Metabolism,Beijing Hospital;3.Institute of Geriatrics,Beijing,100730,China);The Association of Lipoproteins Subfractions with Intimal Medial Thickness of Carotid Artery in Type 2 Diabetic Patients[J];Chinese Journal of Arteriosclerosis;2007-08
5 LV Xiao-hong~*,SU Sheng-ou,WANG Jie-chao,KANG Su-xian,YUE Yuan,SONG Xiao~*Department of Internal Medicine,the Elders′ Diseases Hospital of Hebei Province,Shijiazhuang 050011,China;Relationship between serum high sensitivity C-reactive protein and intima-media thickness of carotid artery in subjects with type 2 diabetes[J];Clinical Focus;2006-24
6 JIANG Yu,LI Chun-mingTeaching & Research Section of Internal Medicine,Medical School,Yichun University,Yichun 336000,China;Relation between minim albuminuria and fore arteriosclerosis of patients of type 2 diabetic mellitus[J];Clinical Focus;2007-21
7 Feng Ping,et al;Study on the relationship between the plasm level of homocysteine and C-reaction protein(CRP) level and carotic intimal-medial[J];Zhejiang Clinical Medical Journal;2007-10
8 ;测量踝臂指数对冠状动脉硬化程度和心血管事件的预测意义[J];Chinese Journal of Practical Internal Medicine;2007-19
9 JIANG Yi-nong,LU Yan.The First Affiliated Hospital of Dalian Medical University,Dalian 116011,China;Early evalutaion of the structure and function of vessels in patients with hypertension[J];Chinese Journal of Practical Internal Medicine;2009-01
10 LU Yan,LU Yi-qun,LI Hong-xia(1.Dept of Endocrinoloy,2.Dept of Cadiology,the First hosipital Affiliated to Suzhou University,Jiangsu Suzhou 215006,China);Relationship Between the Levels of Serum 8-OHdG and Macrovascular Disease in Type 2 Diabetic Patients[J];Suzhou University Journal of Medical Science;2007-05
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved