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《Progress of Anatomical Sciences》 2011-02
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Genetic polymorphisms of 17 Y-STR loci in Han population in the western aera of Shandong province of China

HOU Wei-guang1,ZHANG Lei2,YANG Yong-li1,LIU Xue-feng1,YANG Xiao-lin1,REN Fu1(1. Research Institute of Anthropology,Liaoning Medical College,Jinzhou 121000;2.Liaocheng Institute of Criminal Science and Technology,Liaocheng 252000 China)  
Objective To investigate the genetic polymorphisms of 17 Y-chromosomal short tandem repeats(STR) loci of Han population in the western area of Shandong province and to evaluate their forensic applicability values. Methods Blood samples were collected from 250 unrelated healthy male individuals of Han population in the western area of Shandong province. 17 Y-STR loci were amplified in one tube by using AmpFLSTR Y-filerTM PCR amplification Kit,and the genotypes were determined using Genescan and Gnentype software of ABI 3100XL DNA sequencer and then the frequency of alleles and genotypes of group was obtained. Results 140 alleles were observed at 17 Y-STR loci,the frequency ranged from 0.0040 to 0.640 and the gene diversity ranged from 0.479 to 0.9664. Totally 244 different haplotypes were found and unique in 250 males,two were found in 2 individual,and the observed haplotypes diversity value was 0.9996. Conclusion 17 Y-STR loci are highly polymorphic in Han population in the western area of Shandong province and suitable for genetics and forensic research.
【CateGory Index】: Q987
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