CHARACTERISTICS OF MITOSIS OF NERVE CELLS IN THE CEREBRAL CORTEX OF ADULT MAMMALS AFTER TRAUMA
Huang Lianbi, Yang Shuzhen, Xu Jing(Department of Histology and Embryology, Zhongshan Medical College)
After partial decortication of the parietal cortex of adult rats, division of neurons and glial cells as well as proliferation of macrophages, endothelial cells, pericytes, around the damaged cortical area were observed. The criteria for differentiating mitotic neurons from other cell components especially neuroglia are: (1) the cell body of a dividing neuron especially the pyramidal type is considerably larger than glial cells, and is slightly larger than the adjacent resting neurons of similar type; (2) a dividing neuron has characteristic cell processes, identifiable as axons and apical dendrites, a morphological feature of pyramidal cells; and (3) the dividing neurons contain Nissl granules.The neurons undergo mitosis were located around the lesion area, 37～500 μm from its border of the lesion. The cortical lamina No. V has more mitotic neurons than any other layers; the explanation for which has been discussed.