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《Chinese Journal of Anatomy》 2006-04
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Genetic relationship between seven minorities in China by four short tandem repeats loci analysis

TENG Shao-Kang XU Lin CAO Lin-Zhi WANG Ping ZHAO Li-Juan HUANG Shi-Ning CHEN Zu-Cong (Youjiang Medical College for Nationalities,Baise 533000,China)  
Objective:To investigate the distribution of four short tandem repeats (STR) loci (D5S818,D7S820, D13S317,and vWA)in Heiyi Zhuang Ethnic in Guangxi autonomous region and to study the genetic relationship between 7 minorities.Methods:Totally 152 unrealated individulas were analyzed by STR genescanning marked by fluorescence.Genetic distance was computed and phylogenetic tree was constructed for studying the genetic rela- tionship between 7 minorities.Results:The average heterozygosity in the four STR loci was 0.781 4;the average polymorphism information content was 0.737 5;the accumulative discrimination power was 0.992 880 9,and the accumulative probability of paternity exclusion was 0.992 880 9.All 7 populations were clustered into 2 groups. Uzbek,Uigur,Yugu,Bai,She,and Heiyi Zhuang Ethnic of GuangXi were in the same group,and eastern Mon- golia alone was another group.Conclusion:The data obtained are highly polymorphisms.Genetic relationship be- tween Uzbek and Uigur,Heiyi Zhuang and She is closer.
【Fund】: 国家自然科学基金(30260044);; 广西右江民族医学院2005年重点项目
【CateGory Index】: R394
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