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《Chinese Journal of Interventional Imaging and Therapy》 2005-04
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Combined injection of collagenase and ozone for treatment of lumbar disk herniation

MENG Xiao-dong~1*, WANG Guang-zhou~1, XIAO Yue-yong~2(1.Department of Pain Treatment, Beijing Fangshan Hospital of TCM, Beijing 102400, China; 2.Department of Radiology, PLA General Hospital, Beijing 100853, China)  
Objective To study the clinical application of combined injection of collagenase and ozone for treatment of lumbar disk herniation. Methods Fifty patients with lumbar disk herniation were injected 5-10 ml of 60 μg/ml ozone intradisklly. Then the needle was retraded to the center of herniated nucleus pulposus (HNP), and a 2 ml of 600 U collagense and 5 ml of 60 μg/ml ozone were injected intrahernially via post route. Results All patients were followed up at 1 week,3 and 6 months. The best therapeutic outcome was obtained 6 months after the injection, and the best, good and poor therapy rate were 44%, 48% and 8%, respectively. Conclusion Combined injection of collagenase and ozone is a minimally invasive and effectively method for treatment of lumbar disk herniation.
【CateGory Index】: R681.5
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【Co-references】
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