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《Chinese Journal of Interventional Imaging and Therapy》 2008-01
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Clinical value of MSCT guided cool-tip radiofrequency ablation for refractory malignant tumors

GAO Jian-hua1, ZHAO Xiang-sheng1, SHANG Jian-biao2 (1.Department of Radiology, 2. Department of Oncology, Guangdong Jiangmen Wuyi Hospital of TCM, the Six Affiliated Hospital to Jinan University, Jiangmen 529031, China)  
Objective To evaluate the safety and efficacy of MSCT guided percutaneous cool-tip radiofrequency ablation treatment for refractory malignant tumors. Methods Eighty four lesions (diameter 3.0—15.0 cm, mean 8.5 cm) in 76 refractory malignant tumor patients underwent percutaneous MSCT guided cool-tip radiofrequency ablation (temperature 58—90℃, time 15—120 min). Treatment plan system was adopted based on computed tomography imaging before the procedure. The acute complications were observed immediately post operation and the efficacy was observed every 3 months after the procedure. The survival rate was analyzed. Results The procedure of percutaneous MSCT guided cool-tip radiofrequency ablation in 84 malignant tumors were all successful. No severe complications occurred. The complete response rate was 17.86% (15/84), the partial response rate was 53.57% (45/84), resulting a 71.43%(60/84)overall response rate. The survival rates of 6, 12, 18 and 24 months after the cool-tip radiofrequency ablation operation was 90.79%, 63.16%, 36.84% and 14.47%, respectively. Conclusion MSCT guided percutaneous cool-tip radiofrequency ablation is a minimally invasive, safe and effective method for treatment of refractory malignant tumors.
【CateGory Index】: R730.5
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