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《Chinese Journal of Interventional Imaging and Therapy》 2009-02
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Clinical application of percutaneous transhepatic biopsy of hepatic focal lesions guided by contrast-enhanced ultrasound

ZHOU Ping-an1,LIN Li-wu2,XUE En-sheng2,HE Yi-mi2,GAO Shang-da2,LIN Xiao-dong2(1.The Second Department of Ultrasound,YanAn University Affiliated Hospital,YanAn 716000,China;2.Department of Ultrasound,Fujian Medical University,Fuzhou 350001,China)  
Objective To assess the clinical value of percutaneous transhepatic biopsy of focal hepatic lesions guided by contrast-enhanced ultrasound.Methods Two hundred patients with focal hepatic lesions were randomly divided into two groups.All patients underwent percutaneous transhepatic biopsy.One group underwent biopsy indirectly guided by contrast-enhanced ultrasound(experiment-group,one hundred cases),another group underwent biopsy guided by conventional ultrasound(control-group,one hundred cases).The biopsy achievement ratio,puncture times and accurate diagnosis ratio of different character nodules were compared between two groups.Results The biopsy achievement ratio of experiment-group was 100%,higher than that of control-group respectively(94%,P0.05).The average times of puncture of experiment-group was 1.00±0,lower than that of control-group(1.12±0.41,P0.05).The biopsy achievement ratio of lesions diameter more than 5 cm of experiment group and control group was 100%,97.56% respectively(P0.05),accurate diagnosis ratio was 100% and 87.80% respectively(P0.05),while the biopsy achievement ratio of lesions diameter smaller than 5 cm was 100% and 93.22%,respectively(P0.05),accurate diagnosis ratio was 96.42% and 93.22% respectively(P0.05).The biopsy achievement ratio of HCC nodules after PEI of experiment group and control group was 100%,89.74%(P0.05),accurate diagnosis ratio was 100% and 84.61%,respectively(P0.05).Conclusion Contrast-enhanced ultrasound can improve the biopsy achievement ratio,accurate diagnosis ratio of percutaneous transhepatic biopsy.Especially for the lesions diameter more than 5 cm and HCC nodules after nonoperative therapy,contrast-enhanced ultrasound is helpful to decrease the false negative results of biopsy and the average times of puncture.
【CateGory Index】: R445.1;R446.8
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