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《Bulletin of The Academy of Military(Medical Sciences)》 1987-06
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THE IMMUNOSTIMULATING EFFECT OF A CRUDE EXTRACT OF LYCIUM BARBARCEM L. ON MOUSE T LYMPHOCYTES

Geng Changshan et al (Institute of Pharmacology and Toxicology,Academy of Military Medical Sciences)  
LBP,a crude extract of Lycium barbarcem L.,increased the spleen weight and percen tage of T lymphocytes in peripheral blood in mice at dosages ranging from 5 to 50 mg/kg/day i.p.for 7 days.LBP did not alter the thymus weight at 5~10 mg/kg,but caused a weight decrease at 25~50 mg/kg.LBP potentiated the incorporation of ~3H-thymidine into thymus cells at doses of 50~200 mg/kg and at doses of 5~100 mg/kg induced by ConA. LBP doses at 25,50 or 100mg/kg were equally effective in increasing the incorporation of ~3H-thymidine induced by low concentration of ConA (5~40/μg/ml),while large dose of LBP was more effective to increase the incorporation induced by a high concentration of ConA (60/μg/ml).These results suggested that LBP potentiated the proliferation of T-lymphocytes under suitable conditions.
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