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《Medical Journal of Communications》 2009-06
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The study of HepG2 hepatic carcinoma cell’s apoptosis induced by the recombined TRAIL and Fuzhengyiliufang

FENG Quanlin, CAO Xiaolei1(Nanjing Traditional Medicine University, Affiliated Kunshan Hospital of Nanjing Traditional Medicine U- niversity,Jiangsu 215300; 1Medical College of Nantong University)  
Objective: To study the recombined solubilitied human TRAIL and Fuzhengyiliufang in the HepG2 hepatic carcinoma cell’s apoptosis. Methods: The HepG2 cells with recombined solubilitied human TRAIL and Fuzhengyiliufang were treated, and then the cell survival rate was detected by MTT, and the cell apoptotic index, by flow cytometry. Results: Fuzhengyiliufang could promoted TRAIL to induce cells apoptosis in the dose-dependent and time-dependent way, and at the 105mg/ml the and 24 hours, the effects reached the high level. Conclusion: Fuzhengyiliufang could promote the HepG2 cells apoptosis induced by TRAIL.
【Fund】: 国家自然科学基金(30772014)
【CateGory Index】: R735.7
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【Co-citations】
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