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《MYCOSYSTEMA》 1999-04
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EFFECT OF SACCHAROMYCES CEREVISIAE BD101Cu--METALLOTHIONEIN ON RESISTINGIRRADIATION DAMAGE IN G12 CELLS

XUE Hong--Wei; LIN Wei-Ci; AN Dan(College of Public Health, Beijing Medical Unversity, Beijing 100083)SHU Jian--Fen; LIU Su--Pin; LIN Zhi--Lan(College of Life Sciences, Peking university, Beijing 100871)  
The effects of Cu-methllothionein from Saccharomyces cerevisiae(BD101 Cu-MT) on micronucleus formation and DNA sbrand breaks in g12 cellsinduced by 60Co r ray were investigated using cytochalasin B--blocked method andsingle cell electrophoresis assay. The results have shown that the trentment of 10 and50ug /mL BD101 Cu--MT could decrease the ratio of micromucleated binucleated cellsinduced by 1 or 3 Gy r--ray and inhibit the increase in frequency of comet cells anddistance of migration of nucleur DNA induced by 1 Gy r--ray. R suggest that there isa antagonistic effect of BD101 Cu-MT on genetic damage in g12 cells induced by y--ray.
【Fund】: 国家自然科学基金!39737021
【CateGory Index】: R37
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【Citations】
Chinese Journal Full-text Database 3 Hits
1 Lin Zhi-lan; Hao Fu-ying; Wang Long; Jia Le; Tian Feng; Li Qi(The College of Life Science, Peking University, Beijing 100871, China);STUDY ON ANTIOXIDATION OF SACCHAROMYCES CEREVIAE Cu-METALLOTHIONEIN[J];MYCOSYSTEMA;1997-04
2 JIA Le; WANG Long; LIN Zhilan; XUE Hongwei; WEI Xuetao; LIN Weici (College of Life Sciences, Peking University, Beijing 100871)(College Of Public Health, Beijing Medical University, Beijing 100083);EFFECT OF SACCHAROMYCES CEREVISIAE BD101 Cu-MT ON RESISTING IRRADIATION DAMAGE IN YEAST AND MICE[J];MYCOSYSTEMA;1999-01
3 LuoYing, Sun Zhixian. Yang Ruibiao. ZhangZhensheng. (Institute of Radiation Medicine,Beijing 100850).;Quantitative Analysis of DNA StructureChanges in Individual Irradiated Cells.[J];PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS;1994-05
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 MA Fu-rong,JIA Le,REN Xuan,YANG Feng-Ling,CHENG Cheng(College of Life Sciences,Shandong Agricultural University,Taian 271018,China);Selection of Molybdenum-enriched Saccharomyces cerevisiae Strain and Study on Its Biological Function[J];Shandong Agricultural Sciences;2008-06
2 LI Hong jun1*, WANG Qi en2, YU Li zhang3, DING Yi3, LIOU Li bo3, GUO Ying lu3 1.Daxing Male Hospital, Wu Jieping's Medical Foundation, Beijing 102600, P.R.China; 2.Public Health College of Beijing University, Beijing 100083, P.R.China; 3.Institute of;Detection of Cell Apoptosis Induced with Anti-Fas Antibody in Bladder Carcinoma Cell Line by Single Cell Gel Electrophoresis[J];Chinese Journal of Cancer;2002-01
3 ZHANG Bo (College of Applied Sciences and Humanities of Beijing Union Unversity,Beijing 100083,China);Applications of Single Cell Electrophoresis(SCGE) in Monitoring Environmental Pollutant[J];Journal of Beijing Union University;2005-01
4 ZHANG Bo, LIU Cheng yun, MENG Zi qiang (The Institute for Environmental Medicine and Toxicology, College of Life science and Technology, Shanxi University, Taiyuan 030006);Application of Single-cell Gel Electrophoresis Technique to Monitoring of Environmental Pollutants[J];Environmental Science and Technology;2003-04
5 LIU Zhi-yong~1,WEI Guo-lin~2(1.Jiangxi Labor Sanitation & Occupational Disese Prevention and Treatment Institute,Jiangxi Nanchang 330006 PRC)2.Jiangxi Nanchang Kelin Biotechnology Co.Ltd,Jiangxi Nanchang 330029 PRC);Development of Metallothionein Studies[J];Jiangxi Science;2004-02
6 JIA Le; WANG Long; LIN Zhilan; XUE Hongwei; WEI Xuetao; LIN Weici (College of Life Sciences, Peking University, Beijing 100871)(College Of Public Health, Beijing Medical University, Beijing 100083);EFFECT OF SACCHAROMYCES CEREVISIAE BD101 Cu-MT ON RESISTING IRRADIATION DAMAGE IN YEAST AND MICE[J];MYCOSYSTEMA;1999-01
7 LIU Suping LIANG Shuang LI Furong LIN Zhilan (The College of Life Sciences, Peking University, Beijing 100871);STUDY ON PROTOPLAST ELECTRIFUSION OF METALLOTHINEIN PRODUCING YEAST STRAINS[J];MYCOSYSTEMA;1998-04
8 QUAN Xian-qing,GAO Xiang( Department of Biology,Linyi Teachers' College,Linyi Shandong 276005,China);Plant Metallothionein and Its Function in Scavenging Hydroxyl Radical[J];Journal of Linyi Teachers' College;2003-06
9 Xing Xiaoyun, Li Mingchun, Hou Wenqiang, Xing Laijun (Department of Microbiology, Nankai University, Tianjin, 300071);PURIFICATION AND CHARACTERIZATION OF COPPER-BINDING PROTEIN IN A COPPER-RESISTANT STRAIN OF SACCHAROMYCES CEREVISIAE[J];JOURNAL OF NANKAI UNIVERSITY;2000-03
10 Wang Long; Jia Le ; Lin Zhilan(College of Life Sciences, PeKing University, Beijing 100871);SELECTION OF MUTANTS FROM METALLOTHIONEIN PRODUCING STRAIN[J];MICROBIOLOGY;1999-02
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 Lin Zhi-lan; Hao Fu-ying; Wang Long; Jia Le; Tian Feng; Li Qi(The College of Life Science, Peking University, Beijing 100871, China);STUDY ON ANTIOXIDATION OF SACCHAROMYCES CEREVIAE Cu-METALLOTHIONEIN[J];MYCOSYSTEMA;1997-04
2 Lin Zhilan;Chang Limei(The College of Life Science, Peking University, Beijing, 100871, China);Metallothionein in Eukaryotic Microorganism[J];PROGRESS IN BIOTECHNOLOGY;1996-03
3 Tie Jianke; Li Lingyuan; Ru Binggen (Deparmet of Biochemistry and Molecular biloogy. College of Life Science,Peking University, Beijing 100871)Ci Yunxiang (Collgeg of Chemistry and Molecular Engineering, Peking University, Beijing 100871);FREE RADICAL SCAVENGING AND DNA DAMAGE PROTECTION BY METALLOTHIONEIN[J];ACTA BIOPHYSICA SINICA;1995-02
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