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《Jiangxi Journal of Medical Laboratory Sciences》 2002-04
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Experimental study of clearing free oxygen radicals by five polysaccharides.

XIE Daze,ZHAN Xuejun,ZHANG Tao,et al.Jiangxi Provincial In sti tute of Medi cal Science,Nan chang330006,China  
Objective To observe the function of clearing free oxygen radicals(O 2- )by five polysaccharides such as lycium chinensis etc.Methods Two chemiluminescence(CL)systems xanthine oxidase Luminescence(XL)and pyrogallol luminescence(PL)to produce O 2- were established.The inhibitory action of five polysaccharide solutions with different contents of sugar on XL and PL system was studied.Results The inhibition rates of the same dose of polysaccharide solutions(0.5mg)on XL system were Lycium chinense Radix astragalus Salvia miltiorrhize Schisandra chinensis Codonopsis pilosula respectively.The order of inhibition rates to PL system was similar to that to XL,but that of Condonopsis pilosula was higher than that of Schisandra chinensis.The difference in inhibition rates among five polysaccharide solutions on O 2- were significant (P0.01).Their inhibition rates on the two CL systems were significantly different,too (P0.05).Conclusion The five polysaccharides such as Lycium chinense etc have relatively high capability of clearing O 2- .They are worth to be studied and developed as antisenility drugs
【Fund】: 江西省卫生厅资助课题
【CateGory Index】: R285
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