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《Jiangxi Journal of Medical Laboratory Sciences》 2005-03
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Experimental study on drug-resistant characteristics of mucoid pseudomonads aeruginosa

YANG Yejian, HUANG Xinghua, CAI Huixing. Foshan Hospital of Traditional Chinese Medicine, Guangdong Foshan 528000, China  
Objecitive To approach into the drug-resistant characteristics of mucoid pseudomonads aeruginosa for choosing the eligible antibiotic in clinic. Methods The microdilution method was applied to detect the sensitivities of common 12 kinds of antibiotics against mucoid and non-mucoid pseudomonads aeruginosa and analysed statistically. Results The sensitive rates of mucoid pseudomonads aeruginosa to amikacin, tobramycin and imipenem were 100%, next to the latter were 93% with ceftazidime, piperacillin-tazobactam, ticarcillin-clavulanic acid, piperacillin and netilmicin, and there were 86% in ticarcillin, 79% in ciprofloxacin, and 47% in trimethoprim-sulfamethoxazole, respectively. Conclusions Drug resistance of mucoid pseudomonads is weak in vitro, and also is obviously weaker than that of non-mucoid pseudomonads aeruginosa(P0.005). It should consider the influencing factor being biomembrance of mucoid pseudomonads aeruginosa while using medcine in vivo.
【CateGory Index】: R446.5
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