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《Chinese Journal of Integrated Traditional and Western Nephrology》 2002-06
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Experimental Study of Bao Shen Mixture on Mesangial Proliferative Glomerulonephritis

JIA Xiuqin,GONG Xuezhong,ZHANG Yongfeng,et al Institute of Integrated Traditional Chinese and Western Medicine, Shenzhen Second people's cross Hospital,Shenzhen (518035)  
Objective:To explore the effect and mechanism of Bao Shen Mixture on a rabbit model of mesangial proliferative glomerulonephritis(MsPGN)in 24 h urinary protein,renal function and blood-lipid.Methods:A rabbit model of MsPGN was created according to Wu Heng Shengs article.24 h urinary protein,renal function and blood-lipid were observed after treatment of Bao Shen Mixture.Results:24 h urinary protein in the model was significantly increased as compared with control.Lipid-metabolism was abnormal.Bao Shen Mixture significantly improve rabbit model of MsPGN in urinary protein and abnormal lipid-metabolism.Conclusions:The mechanisms of Bao Shen Mixture in treating MsPGN may be related to correction of abnormal lipid-metabolism .
【Fund】: 广东省中医药管理局资助项目 (No .980 8)
【CateGory Index】: R277.51
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