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《Chinese Journal of Integrated Traditional and Western Nephrology》 2013-09
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Comparison of Anemia Between Diabetic Nephropathy and Non - diabetic Nephropathy and Analysis of Its Relevant Factors

ZHANG Shaochong;CHENG Dongsheng;WANG Niansong;Department of Nephrology,Shanghai Sixth People's Hospital,Shanghai Jiaotong University;  
Objective:To compare the characteristics of anemia in patients with stage 3 Chronic Kidney Disease(CKD3) and patients with Diabetic nephropathy(DN) as well as to evaluate their relevant factors.Methods:Methodology A total of 91 patients with diagnosis of CKD3 who were in-hospital during Feb.2012 to May 2013 in Shanghai Sixth Hospital Department of Nephrology were enrolled including 42 cases of DN and 49 cases of non-DN.Values were analyzed and compared between them such as Red Blood Cellcounts(RBC),hemoglobin,total protein,albumin,erythropoietin(EPO),ferritin,total iron binding,serum iron,folic acid,Vitamin B12,serum creatine,BUN,Ca、P、PTH、25OHD3 etc.Results:In 42 cases of DN,the incidence of anemia was 67%,In 49 cases of non-DN,the incidence of anemia was 39%,the levels of RBCs,hemoglobin,albumin and serum iron were remarkably lower in DN group than in non-DN group(P 0.05) while DN group had a much higher level of EPO than non-DN group(P 0.05).Conclusion:The level of anemia in non-DN is much lower than it in DN.This probably have close relationship with hypoalbuminia,extrarenal factors and metabolism.
【Fund】: 国家自然基金面上项目(No.81270824);; 上海市国际科技合作基金资助项目(No.11410708500);; 上海市科委引导类项目(No.114119a6100);; 上海市科委项目(No.11DZ1921904);; 上海市科委基础研究重大项目(No.11DJ1400101);; 上海市科委重大项目(No.11DZ1973103)
【CateGory Index】: R692.9;R587.12
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【Co-citations】
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