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《Acta Academiae Medicinae Jiangxi》 2007-03
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Effects of Gypenosides on Enzyme Activity and Phagocytic Capacity of Peritoneal Macrophage in Mice

DUAN Bing-Nan,CHENG Qin-lin(Department of Histology and Embryology of XiangYa Medical College of Central South University,changsha 410013,China)  
Objective To observe effects of Gypenosides on enzyme activity and phagocytosis of peritoneal macrophage(PM) in mice.Methods forty mice were randomly divided into four groups: the normal control group and the experimental groups with different doses of Gypenosides.Intragastric administration with saline was conducted in the normal control group;intragastric administration with Gypenosides was performed in the experiment groups;14 days later,the changes of ACP and LDH activity in PM and the phagocytosis of PM were determining.Results Compared with the control group,enzyme activity of ACP and LDH and phagocytosis of PM were increased in the experimental groups with different doses of Gypenosides;compared with the low doses of experimental group,enzyme activity of ACP and LDH and phagocytosis of PM were increased in high and average doses of experimental groups.Conclusion Gypenosides plays an important role in promotion on activity of ACP,LDH and phagocytosis of PM in mice.There are appropriate dosages on enzyme activity and phagocytosis of PM.
【CateGory Index】: R285.5
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