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《Jiangxi Medical Journal》 2011-09
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Expression of matrix metalloproteinase-2,7,9 in congenital muscular torticollis and its clinical significance

Liu Qiaofeng,Wu Xinle,Du Xiangping.Grade 2006 postgraduate,medical college of Nanchang university,Jiangxi nursing occupation technical college,Nanchang,330006,China  
Objective To observe the expression of matrix metalloproteinase-2,7,9(MMP-2,7,9)in sternocleidomastoid muscle of congenital muscular torticollis,and to explore pathogenesis of sternocleidomastoid muscle fibrosis.Methods Immunohistochemical method was performed to investigate the expression of MMP-2,7,9 in the control group and the experimental group.Results By the immunohistochemical method,there were scanty green collagen fibers in the control group and numerous in muscle type group and fibrous type group.The expression of MMP-2,7,9 in the fibrous type group was lower than that in the control group and the muscle type group(P 0.01).The expression of MMP-2,7,9 were similar between the control group and the muscle type group(P0.05).Conclusion The reducing expression of MMP-2,7,9 may be important factors of collagen deposition and sternocleidomastoid muscle extracellular matrix fibrosis aggravation.
【CateGory Index】: R726.8
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