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Dffects of Acute Hypoxia 5 km on Immune System

Gao Mei, et al(132013 Jilin PLA Air Force Junior College of Medicine)  
Objective The purpose of this study is to explore the effect of acute hypoxia 5 kmon immune system,Method Kunming mice were divided into three groups:hypoxia group 30min. 60 min,and the control group. experimental group underwent hypoxic exposure (5 kmfor 30 min, 60 min). In altitude chamber. mice was killed. IL-1, IL-2,IL-3 level was measuredthe method of H-TdR incorporation,thymuscyto proliferation and bonenarrowcyto proliferation of mice- Resuils the level of T lymphocyto trans formation. IL-1, IL-2 in experimentalgroup: 30 min,60 min was significantily suppressed as compared control (P<0. 05) ;while Bcell,IL-3 of experimental group was did not changed obviously as compard with contral. Conclusion 5 km acute hypoxia can suppress cell mediated immunity function of mice.
【CateGory Index】: R371
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