Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
《Laboratory Medicine and Clinic》 2009-12
Add to Favorite Get Latest Update

Study on diagnostic value of determination of liver enzymology in liver disease

LUO Rong1,WANG Wei1,LI Zhuo-cheng1,XIONG Ying2.1.Department of Laboratory Medicine;2.Department of Gastroenterology,Shenzhen Second People's Hospital,Shenzhen 518035,China  
Objective To evaluate the diagnostic value for the examination of liver enzymology in the patients suffering from liver diseases.Methods Serum values of NAG,AFU,LAP,ASTm,GLDH,ADA,AST,ALT,ALP,GGT,5'-NT and CHE were determined with auto-biochemical analyzer and analyzed statistically in 308 hepatitis patients and 115 healthy subjects.Results In acute hepatitis patients,the mean values of NAG,AFU,LAP,ASTm,GLDH,ADA,AST,ALT,ALP,GGT and 5'-NT increased significantly compared with healthy subjects.In liver cirrhosis patients,the mean values of NAG,LAP,ASTm,GLDH,ADA,AST,ALP,GGT and 5'-NT increased significantly while that of CHE decreased significantly compared with healthy subjects.In severe hepatitis patients,the mean values of NAG,AFU,ASTm,GLDH,ADA,AST,ALT,ALP,GGT and 5'-NT increased significantly while that of CHE decreased significantly compared with healthy subjects.In hepatocellular carcinoma,the mean values of NAG,AFU,LAP,ASTm,GLDH,ADA,AST,ALP,GGT and 5'-NT increased significantly while that of CHE decreased significantly compared with healthy subjects.Conclusion ALT,LAP,AFU,ASTm,AST and ALP are valuable markers for diagnosing acute hepatitis,ADA,AST,5'-NT,GGT and CHE are valuable marker for diagnosing liver cirrhosis,AST,ALT,ASTm,CHE,AFU and GLDH are valuable marker for diagnosing severe hepatitis,and AFU,5'-NT,GGT,ALP and LAP are valuable markers for diagnosing hepatocellular carcinoma.All items are less valuable for diagnosing chronic hepatitis and alcoholic hepatitis.
【Fund】: 深圳市科技计划项目资助(200703168)
【CateGory Index】: R575;R446.1;R446.6
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
【Citations】
Chinese Journal Full-text Database 3 Hits
1 CHEN Ping-hu, LI Jian,LIU Pei-guang (The Department of Gastroenterology, the People's Hospital of Zhangjiang,Guangdong, Zhanjiang 524037, China);Effect of Chemotherapy on the Liver Function of HBV Carrier Cancer Patient[J];Journal of Tropical Medicine;2006-09
2 ZHU Jian-yun, CHEN You-ming, XIE Shi-bin,GAO Zhi-liang (Department of Infection Diseases, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China);Study on Severe Viral Hepatitis During Pregnancy[J];Journal of Tropical Medicine;2007-03
3 LUO Rong,LI Zhuo-cheng,CHEN Jian-xiong,XION Ying(Department of Laboratory Medicine,Shenzhen Second People's Hospital, Shenzhen 518035,China);Dynamic Changes of mAST/AST Ratio and Their Clinical Significances in Liver Damage[J];Journal of Tropical Medicine;2008-06
【Secondary Citations】
Chinese Journal Full-text Database 10 Hits
1 WANG Bo Liang 1, ZHONG Yue Xia 1, GU Bing Quan 2, CAO Yi Zhan 1, LU Jiang 1, TIAN Xiao Xi 1 1Department of Emergency, 2Department of Clinical Laboratories, Tangdu Hospital, Fourth Military Medical University, Xi'an 710038, China;Application of leucine aminopeptidse in the diagnosis of hepatic diseases[J];Journal of The Fourth Military Medical University;2003-09
2 Zhou Yong-Lie(Department of Laboratory Medicine.Zhejiang Provincial people's Hospital.310014);KINETIC ASSAY OF SERUM ISOCITRATE DEHYDROGENASE[J];JOURNAL OF CLINICAL LABORATORY SCIENCE;1995-04
3 PAN Xing-hua1,2, PANG Rong-qing2, CHEN Xi-gu1, LIU Jian-kun2,HE Zhan-long3,WANG Hui-xian2,ZHANG Bu-zhen2,WANG He-hua2, YANG Yong-qin2, QU Lu2(1. Medical Experimental Animal Center of Sun Yat-sen University,Guangzhou 510080;2. Medical Experimental Department of Kunming General Hospital of Chendu Military District of PLA,Kunming 650032; 3. Animal Center of Kunming Medical Biology Institute of Xuehe Medical University of Chinese Medical Academy,Kunming 650032,China);Application of Autologous Bone Marrow Stem Cells for the Treatment of Acute Liver Necrosis in Monkey[J];Journal of Tropical Medicine;2006-03
4 CHEN Li-mei(Guancheng Hospital, Dongguan, Guangdong,Dongguan 523000,China);A Clinical Study on the Effect of Anti-HBV Ig on Intrauterine HBV Infection[J];Journal of Tropical Medicine;2006-03
5 CHEN Ping-hu, LI Jian,LIU Pei-guang (The Department of Gastroenterology, the People's Hospital of Zhangjiang,Guangdong, Zhanjiang 524037, China);Effect of Chemotherapy on the Liver Function of HBV Carrier Cancer Patient[J];Journal of Tropical Medicine;2006-09
6 ZHU Jian-yun, CHEN You-ming, XIE Shi-bin,GAO Zhi-liang (Department of Infection Diseases, the Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China);Study on Severe Viral Hepatitis During Pregnancy[J];Journal of Tropical Medicine;2007-03
7 ZHANG Feng-ju, ZHAI Chun-xi (The Second People’s Hospital of Liaocheng, Linqing 252601, Shandong, China);Observation of serum monoamine oxidase activity in hepatopathy[J];Modern Jorunal of Integrated Traditional Chinese and Western Medicine;2004-04
8 Li Hang Li Lequn Wan Likai et alTumor Hospital Affiliated to Guangxi Medical University, Nanning;The Value of The Measurement of Fructose 1,6-Diphosphate Aldolase in Evaluating of Tumorous Tissue Damage by Percutaneous Ethanol Injection Therapy of Hepatocellular Carcinoma[J];Chinese Journal of Clinical Oncology;2004-06
9 Shu Jian-De; Xie Hong; Chen Xin-Gang et al (Department of Biochemistry, Qiannan Medical Collge, Guizhou 558003);Diagnostic Value of Aldolase-A Determination by ELISA of Human Aldolase-A Monoclonal Antibody in Primary Hepatocellular Carcinoma[J];CHINESE JOURNAL OF CLINICAL ONCOLOGY;1996-10
10 XUE Ai ling,GAO Zong ling,GUO Hai ge (Central hospital in Shangqiu city Henan province China 476000);The Diagnostic Value and Limitations of Serum Monoaminoxdase Examination[J];Chinese Journal of Misdiagnostics;2002-06
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved