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《Laboratory Medicine and Clinic》 2014-08
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Application of ER Xian Tang and QI Hai Xiao Ying Tang for the treatment of chronic lymphocytic thyroiditis complicated with hypothyroidism

CHEN Qiong-ke;ZHENG Shi-xia;LIU Jing;Special Traditional Chinese Medicine and Western Medicine Department of Thyroid,the Third People′s Hospital of Chongqing;Endocrine Department,the Third People′s Hospital of Chongqing;  
Objective To explore the curative effects of ER Xian Tang and QI Hai Xiao Ying Tang for the treatment of chronic lymphocytic thyroiditis(CLT)complicated with hypothyroidism.Methods A total of 70patients with CLT complicate with hypothyroidism were divided into treatment group,given Er Xian Tang,Qi Hai Xiao Ying Tang and levothyroxine sodium tablets,and control group,given evothyroxine sodium tablets.Curative effects, and serum levels of triiodothyronine(T3),thyroxine(T4),free triiodothyronine(FT3),free thyroxine(FT4),thyrotropic-stimulating hormone(TSH),thyroglobulin antibody(TGAb),thyroid peroxidase antibody(TPOAb)and so on were compared between the two groups.Results Before treatment,the differences of levels of T3,T4,TSH,FT3, FT4,TGAb,TPOAb and indexes of routine blood test between the two groups were not significant(P0.05),and liver function of patients in the two groups were all without abnormality.After treatment,the effective rate in treatment group was 91.4%,being significantly different with the 74.3%in control group(P0.05).After treatment, levels of T3,T4,FT3,FT4and TSH in the two groups all return to normal range,and levels of TGAb and TPOAb in treatment group were reduced,being significantly different with levels detected before treatment and with levels of control group(P0.05).In treatment group,the dosage of levothyroxine reduced significantly(P0.05).Thyroid volume reduced significantly only in treatment group(P0.05).Conclusion Er Xian Tang and Qi Hai Xiao Ying Tang could effectively regulate immune function,reduce levels of TGAb,TPOAb and thyroid volume in patients with CLT complicated with hypothyroidism.
【Fund】: 重庆市卫生局资助项目(2006-20)
【CateGory Index】: R581
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