INFECTION AND SUSCEPTIBILITY OF METHICILLIN-RESISTANT STAPHYLOCOCCUS IN CHILDREN
ZHU Ze-hang,CAI Yi-ting,YI Jun-wen(Shanghai No.1 People's Hospital affiliated to Shanghai Jiaotong University,Shanghai 200080,China)
Objective To explore the situation of methicillin-resistant staphylococcus(MRS) infection and its resistance in children.Methods The data of isolation and resistance of MRS in the last three years(Jan 2001-June 2004) were analysed by statistical method. Results The detection rate of MRS(including methicillin resistant coagulase negative staphylococcus(MRCNS),methicillin resistant staphylococcus aureus(MRSA)) in all of the specimen was 60.1%.There was no significant difference in all kind of MRCNS detection(P0.05).The deteection rate of MRCNS was significantly higher than MRSA(P0.05). The detection rate of MRS in blood(81.6%)or in urine(72.0%) was significantly higher than that in pus(52.3%) or in throat swab(44.7%)(P0.05).All of the staphylococci were sensitive to vancomycin and rifampin.The MRS isolates were partially sensitive to amikacin,ciprofloxacin,and fosfomycin. Moreover,they were poorly sensitive to erythromycin,clindamycin,and trimethoprim/sulfamethoxazole.Conclusion MRS strains have become the major course of children's infection.The detection rate of MRS in children is approaching to that in adults.The detection rate of MRCNS is higher than that of MRSA.Vancomycin becomes the first choice for children's MRS infection.It is important to prevent children from infection.
【CateGory Index】： R725.1