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《Acta Entomologica Sinica》 1980-03
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STUDIES ON THE RESISTANCE OF DIPTEREX-RESISTANT MOSQUITO CULEX PIPIENS PALLENS COQUILLETT——THE RESISTANCE SPECTRUM OF VARIOUS COMPOUNDS AND JOINT ACTION WITH DIPTEREX

TANG ZHEN-HUA ZHANG ZHAO-TUAN CHEN WEN-MEI ZHUANG PEI-JUN SONG WEI-JUN LIU WEI-DEH (Shanghai, Institute of Entomology, Academia Sinica)  
A high level of resistance to Dipterex (more than 240-fold) has been induced in larvae of the mosquito, Culex pipiens pollens Coquillett, by selection of a population collected from Zhabei District, Shanghai, in the laboratory. The Dipterex-resistant strain (RD strain) has developed different levels of cross-resistance to all organo-phosphates tested. It showed a high level of dross-resistance to Dichlorvos (176-fold), Abate (85-fold) and Methyl parathion (51-fold), moderate level of cross-resistance to Malathion (40-fold), Fenthion (39-fold), Azodrin (22-fold), Phoxim (22-fold), Phos-phamidon (17-fold), Ofnack (14-fold), Parathion (13-fold), Sumithion (12-fold), and Ethyl Pirimiphos (11-fold), and low level of cross-resistance (less than 10-fold) to Diazinon, Brsan, Dimethioate, Ethyl Ainphos and Omethioate. It was found that the development of resistance to Dipterex seems to induce a slight negative cross-resistance to Pyrethrum, Tetramethrin, Permethrin and Resmethrin.Synergistic action of 29 compounds with Dipterex was evaluated in the RD strain and the normal strain (SEN strain). TPP, Kitazin, Kitazin-P, TOCP, Malathion, Ersan, Ofnack, Methyl Parathion, Fenthion, Sumithion, and Phosphamidon were all shown to have synergistic effect with Dipterex. Among these compoumds, TPP, Kitazin, Kitazin-P and TOCP had the most effective synergdstic activities with Dipterex, and its co-toxicity coefficients with Dipterex were 5.90, 4.84, 3.05 and 2.76 for the RD strain respectively, The synergistic action was not observed in the SEN strain.
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