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《CHINESE JOURNAL OF ARTERIOSC LEROSIS》 1997-03
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Effects of L-arginine on Atherosclerotic Plaque Area of Aortae and Coronary Arteries in Rabbit with Hypercholesterolemia

JIAO Hong-Li;;LIU Yi-Lin;; WAN La-Xiang;; HU Long-Mei;;YANG He-Ping and YANG Yong-Zong(Molecular Biology Center,Hengyang Medical College,Hengyang 421001, Guangdong Province Yuebei Hospital,Shaoguan 512026, Nanyue Pharmaceutical Factory,Hengyang 421001. C  
Aim A large amount of literature reported that Larginine-nitric oxide (L-Arg--NO) pathway involVed in the formation and progression of atherosclerosis (As)induced by hypercholesterolemia. The purpose of this study is to determine the effects of L-arginine on the atherosclerotic plaque formation.Methods New Zealand white rabbits (n=144 ) were assigned to control group, nifedipine group,isosorbide dinitrate group, L-arginine group and hypercholesterolemic group, respectively. Experiment included a 90 days' treatment and 180 days' treatment.The percentage of atherosclerotic plaque covering aortic and coronary intima was measured.Results The atherosclerotic plaque area was reduced by feeding with L-arginine at l, 1. 5 and 2 g/kg in each day at this study. While in nifedipine treated groups and in isosorbide dinitrate treated groups, the plaque area gave higher values than L-arginine treated groups, but lower than those of hypercholesterolemic groups. The effects of L-arginine on antiatherosclerosis was more significant than nifedipine and isosorbide dinitrate.Conclusion L-arginine exerts strong antiatherosclerotic effect in experimental rabbit. Nifedipine and isosorbide dinitrate has the similar effect but with a slightly weaker action.
【CateGory Index】: R543.5
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【References】
Chinese Journal Full-text Database 8 Hits
1 Zhang Mianzhi et al ( Hebei Medical University );Experimental Research of Chongcao Dihuang Promoting-blood-circulation Decoction for Atherosclerosis[J];China Journal of Traditional Chinese Medicine and Pharmacy;2003-04
2 Li Qi 1, Ouyang Jingping 2, Yu Zhui 3, et al 1. Department of Medical, Wuhan Polytechnic University, Wuhan 430023 2. Department of Pathophysiology, Medical College of Wuhan University, Wuhan 430071 3. Department of Emergency, Zhongnan Hospital of Wuhan University, Wuhan 430071;Effect of Angelica on High Lipid Induced Atherosclerosis in Rabbits Aorta[J];Journal of Hubei College of Traditional Chinese Medicine;2003-02
3 ZHANG Jing-fang~1, YANG Xue-qin~1,WANG Guang-hao~2 (1 Medical School of Jingmen Technical College,Jingmen,Hubei 448000,China;2 Jingmen NO.2 People's Hospital,Jingmen,Hubei 448000,China);The Function of Sodium Ferulae on Atherosclerosis Caused by High Fat Food[J];Journal of Jingmen Vocational Technical College;2004-06
4 HUANG Hong-Lin;YIN Wei-Dong;LIAO Duan-Fang;CHEN Jian-Xiong;TANG Xiao-Qing;LI Bo-Ping;CAO Jian-Guo and YU Lin (Division of Cardiopulmonary Pharmacology,Institute of Cardiovascular Diseases,Hengyang Medical College,Hengyang 421001,Chinas);Effect of Gypenosides on Formation of Atherosclerotic Plaque of Aorta in Hypercholesterolemic Rabbits[J];CHINESE JOURNAL OF ARTERIOSC LEROSIS;1998-04
5 YU Zhui, OUYANG Jing-Ping, LIU Yong-Ming, ZHENG Han-Qiao, YANG Jing-Wei, TU Shui-Zhen, and YANG Hai-Lu [WT6BX](Department of Pathophysiology, Hubei Medical University, Wuhan 430071, China);The Antiatherogenetic Effect of Angelica in Rabbits Aorta[J];CHINESE JOURNAL OF ARTERIOSC LEROSIS;2000-01
6 Si Yan-hong, Shang Zhan-ping, Wang Jia-fu,Jiang Xin-quan, Wang Xin-cheng, Qi Hui, Yao Shu-tong, Song Guo-hua, Department of Pathophysiology, Taishan Medical College, Taian 271000, Shandong Province, China;Interventional effect of propolis on atherosclerosis induced by hyperlipid in rabbits[J];Chinese Journal of Clinical Rehabilitation;2005-35
7 OU YANG Jing Ping, WANG Bao Hua, LIU Yong Ming, YANG Jing Wei, WEI Lei, LI Ke (Dept of Pathophysiology, Wuhan University Medical College, Wuhan 430071);Experimental study of the anti-atherogenesis effects of sodium ferulate in hyperlipidemia rabbit and its mechanisms[J];Chinese Pharmacological Bulletin;2002-02
8 ZHANG Rui-fen,XU Jin-rui1,ZHANG Ming-wei,CHI Jian-wei,ZHANG Yan,WEI Zhen-cheng (Key Laboratory of Functional Food Research Ministry of Agriculture, Guangdong Academy of Agricultural Sciences, Guangzhou,510610; 1 College of Public health, Guangdong Pharmaceutical University,Guangzhou 510310,China);THE ANTI-ATHEROGENIC EFFECTS OF BLACK SOYBEAN COAT ANTHOCYANIN EXTRACTS IN RABBITS[J];Acta Nutrimenta Sinica;2007-05
【Citations】
Chinese Journal Full-text Database 4 Hits
1 Department of Cardiology,People’s Hospital Wang Bingyin,et al;AN OBSERVATION OF ANTIATHEROGENIC EFFECTS OF L-ARGINING I HYPERCHOLESTEROLEMIC RABBIT[J];JOURNAL OF BEIJING MEDICAL UNIVERSITY;1994-03
2 YANG Ai-Lian; TANG Xiao-Qing; WANG XiaoPing; CHEN Yang-Fan; WANG La-Xiang; OU HeSheng; HUANG Zong-Zhi; PENG Jian-Ping; LIU Ge-Xiu; ZHANG Tong and YANG He-Ping(Molecular Biology Center, Hengyang Medical College,Hengyang 421001, China );L-Arginine Improves Endothelium Dependent Vasorelaxation and Reduces the Development of Proliferative atherosclerotic lesions[J];Chinese Journal of Arteriosc Lerosis;1995-01
3 TAN Xiao-Jin; DAI Ai-Guo; WEN Fang; LIAO Wen-Fu(Department of Internal Wedicine. First Affiliated Hospi tal) YANG He-Ping; ZOU Fei-Yan(Institute of Cardiovascular Disease, Hengyang Medical College, Hengyang, 421001)ZUO Gen-Ming(Hengyang Center Hospital,Ch;Effects of L-arginine on Serum Lipid,Lipoprotein, Apolipoprotein, Lipid Peroxide and Hemorheology in Patients with Coronary Heart Disease and Hyperlipemia[J];CHINESE JOURNAL OF ARTERIOSC LEROSIS;1997-01
4 YANG Yong-Zong; CHEN Yan-Fang; LIU Yi-Lin; LIN Xu-Guang; JIAO Hong-Li; WANG Zhou-Lian; DIN Cui-Fen; WAN La-Xian; YANG He-Ping (Molecular Biology Center, The Second Affiliated Hospital, Hengyang Medical College, Hengyang 421001; Guangdong Institute of Card;Effect of L-arginine on Lipoprotein, Nitric Oxide and Lipid Peroxide in Hypercholesterolaemic Rabbits[J];CHINESE JOURNAL OF ARTERIOSC LEROSIS;1995-03
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 Qiu Jiongliang, Chang Yan, Zhu Xinqiang Department of Toxicology, Zhejiang University, Hangzhou\ 310006;USE IN VIVO MULTIPLE ENDPOINTS ASSAY FOR STUDYING ESTROGENICITY OF ENDOSULFAN[J];CARCINOGENESIS, TERATOGENESIS AND MUTAGENESIS;1999-05
2 SHAN Bao-en 1 ,GUO Lan-tao 1 ,DONG Qing 1 ,MA Hong 2 (1.Research Center,The Fourth Hospital of Hebei Medical University,Shijiazhuang,050011,Hebei,China; 2.MD Technologies,Inc.845Pheasant Woods Drive Manchester,Mo63021,USA);Syk Can Influence As_2O_3 Induc ed Brain Tumor Cell Cycle Defects[J];Carcinogenesis,Teratogenesis and Mutagenesis;2005-06
3 SHAN Bao-en1,LIU Dong-qing2,LIANG Wen-jie1,ZHANG Jing1,LI Qiao-xia1(1.Research Center of the Fourth Hospital of Hebei Medical University,Shijiazhuang,050011,China;2.The First Hospital of Handan);The Anti-tumor Effect and Immunoregulatory Activity of PE2 From Rhizoma Menipermi Extracts in Vivo[J];Carcinogenesis,Teratogenesis & Mutagenesis;2006-05
4 SHEN Ye-shou,ZHENG Li-jun,WANG Zheng-liang,GU Li-ping(Laboratory of Glycoconjugate and Glycotechnology, Institute of Biochemistry and Microbiology, Anhui University, Hefei 230039,Anhui, China);Experimental Study on Anti-tumor Effects of Intracellular Polysaccharide from Phellinus Linteus[J];Carcinogenesis,Teratogenesis & Mutagenesis;2007-04
5 Li Guoxian;Analgesic and Central Inhibitory Action of the Essential of Aristolochia Mollisima[J];Journal of Anhui University(Natural Sciences);1989-01
6 CHEN Qin~1, TAO Xia-ping~2 (1.School of Life Science, Anhui University, Hefei230039,China; 2. China Academy of Traditional Chinese Medicine, Beijing100700, China);Experimental study of baochunjing capsules on effect of nourishing kidney and tonic yang[J];Journal of Anhui University(Natural Sciences);2004-03
7 DENG Xu et al (The National Base of Life Science and Biotechnology Education,Northwest A & F University,Yangling,Shaanxi 712100);Preliminary Study on Antimicrobial Activity of Fermentation Broths of Oudemansiella mucida[J];Journal of Anhui Agricultural Sciences;2006-19
8 ZHANG Gui-zhi et al(Animal Science Department,Zhengzhou College of Animal Husbandry & Engineering,Zhengzhou,Henan 450011);Joint Antibacterial Action between TMP and SMM in Vitro[J];Journal of Anhui Agricultural Sciences;2007-36
9 CAI Zhi-hua(Institute of Bio-pharmacies,College of Life Science,Chongqing Normal University,Chongqing 400047);Primary Exploration on the Extraction Technology of Crude Superoxide Dismutase from Chinese Quince[J];Journal of Anhui Agricultural Sciences;2008-05
10 CHEN Jiong-ran et al(Lanzhou Institute of Animal Husbandry and Veterinary,Chinese Academy of Agricultural Sciences,Lanzhou,Gansu 730050);Research on the Effect of the Compound Oral Chinese Medicine on Anti-inflammatory of Mice[J];Journal of Anhui Agricultural Sciences;2010-26
China Proceedings of conference Full-text Database 10 Hits
1 HU Xiao-bo,LIU Yang,ZHANG Xue-nong 1 (Department of Pharmaceutics,School of Pharmaceutical Science,Suzhou University;Jiangsu Suzhou 215123);Study on the anti-tumor activities of pH-sensitive Osthol-Nanoparticles[A];[C];2011
2 WANG Guo-dong WANG Zhu HAN Jun-hua HE Mei Institute of Nutrition and Food Safety,Chinese Center for Disease Control and Prevention,Beijing 100050,China;STUDY OF THE MODULATING EFFECTS OF PHYTOSTEROL ON SERUM LIPID[A];[C];2007
3 ;Study on the Functional Effect of Chufa Functional Component[A];[C];2004
4 Pan Hua-Xin, Wang Pei-Xxun, Zhou Lian, Cao Liu-Ying, Liang Rui-Yan (Immunological Laboratory of Clinical Pharmacology Institute, Guangzhou University of TCM. Guangzhou 510405. China);Comparison of anti-inflammatory and immunosuppress effects of two kind of tablets of tripterygium wilfordii polyglycosidium[A];[C];2006
5 WANG Xiao HU Shixing LIN Shaochun GUO Xuejun ZOU Yihai (Zhongshan Ophthalmic Center, Zhongshan University, Guangzhou, 510060; The Ophthalmology hospital, China Academy of TCM, Bejing, 100040 3 LAC, Guangzhou University of TCM, Guangzhou, 510405);Effects of the Lighting Decoction in models of Acute Light Damage in Rat's Retina[A];[C];2006
6 Zhang Dawei Bing Guoqiang LiPing Yang Donghua Yu Yanbo Liu Zhanjun Guo Chao Xu Caiyun (Center of Laboratory Animal, School of Basic Medical Sciences, Jilin University, Changchun, Jilin, 130021; Laboratory Center, College of Physical Education, Jilin University, Changchun, Jilin, 130012; Observation Room of Laboratory Animal, No. 2 School of Clinical Medicine, Jilin University; Laboratory Animal Room, Changchun Biological Products Research Institute; Changchun Jingyou Medicine Joint-stock Limited Company);Experimental animal barrier environment commonly used disinfection drugs stimulant quality and toxic experiment (五) --Inspiration toxicity experiment of 2% content peracetic Acid solution[A];[C];2006
7 HONG Hua~1,ZHAO Xiang-ren~2,LIU Huai-yu~1 (1.Laboratory Animal Center of Jilin University,Changchun,Jilin,130021 2.Dentrial Medical Colege of Jilin University,Changchun,Jilin,130041 );Safety Reevaluation of Tiopronin Injection[A];[C];2010
8 Suofei -ya Huang peiyou li qiang Wu liya. yiming ( College of Life science and techonolgy, Xinjing University, Wurumuqi, xinjing830046 College of Pharmacy, Xinjiang Medical University, Wurumuqi, Xinjiang 830011);The actue virulence of Cumin Seed Oil and protective effects on the experimental gastric ulcer[A];[C];2005
9 Chen Yan,Wu Li-ya,Chen Rong(Traditional Chinese physician hospital of Xinjiang autonomous region,Urumqi 830054,china);Experimental Study on Protective Effect of Celery root Against Acute Liver Injury[A];[C];2008
10 Yan Zen-kai1, Zhu Hui-ling2, Hu Chun-ju3, Huang Xian-ju2 (1. Department of Chemistry, Hanshan Normal University, Chaozhou 521041; 2. Medical School of Yangtze University, Jingzhou 434000; 3. Department of medical, Hanshan Normal University, Chaozhou 521041);Isolation and Pharmacological Action of Dihydromyricetin[A];[C];2006
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 LIU Ya-qiong1, ZHU Ling-qun1, ZHANG Yun-ling2, ZHENG Hong2, LIU Xue-mei2(1 Key Laboratory of Chinese Internal Medicine of Ministry of Education, DongzhimenHospital, Beijing University of Chinese Medicine, Beijing 100700 China; 2 Department of Neurology, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China; 3Expetiment Center, Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100078, China);Infulence of Kudiezi Injection on expression of NF-κB and adhesion molecules in human brain microvascular endothelial cells after high glucose damage[J];China Journal of Traditional Chinese Medicine and Pharmacy;2010-02
2 JIANG Ming-dong~(1,3),PENG Zhi-ping~(2,3),YIN Xiao-ling~(3),LI Shao-lin~(3)(1.The Irradiation Treat Center of Ninth People Hospital in Chongqing,Chongqing,400016,China;2.The First Affiliated Hospital in Chongqing Medical University,Chongqing,400016,China;3.Department of Nuclear Medicine in Chongqing Medical University,Chongqing,400016,China);Establishment of Rabbit Model of Atheromatous Abdomial Aorta[J];Progress In Veterinary Medicine;2005-09
3 Hu Yunqiao,Zhu Dongynu,Zhen Xun et al;The blood fat survey and nursing strategy for in-patient of coronary heart disease[J];JOURNAL OF NURSES TRAINING;2000-07
4 (received Nov. 28, 1996, revised April 22, 1997)Yang Heping; Yang Yongzong (Center of Molecular Biology, Hengyang Medical College, Hengyang 421001);Regulation of Proliferation and Apoptosis of Smooth Muscle Cell in Atherosclerosis[J];HIGH TECHNOLOGY LETTERS;1997-08
5 YU Ye-rong. Department of Endocrinology, West China Hospital, Sichuan University, Chengdu 610041, China;Insulin resistance and abnormal function of vascular endothelium cell:is high blood free fatty acid play a key role[J];International Journal of Endocrinology and Metabolism;2006-03
6 Ouyang Jingping, Wang Xiong,Muller S, Department of Pathophysiology,Basic Medical College, Hubei Medical University,Wuhan 430071,China;The Reverse Effect of Angelica on the Reorganization of Cytoskeleton Induced by TNF-α[J];JOURNAL OF HUBEI MEDICAL UNIVERSITY;2000-01
7 Yan Xiaohong,Ouyang Jingping,Tu Shuzhen,et al (Department of Pathophysiology,Basic Medical College,Hubei Medical University,Wuhan 430071,China);Protective Effects of Angelica on Oxidized Low density Lipoprotein Induced Damages of Vascular Endothelial Cells[J];JOURNAL OF HUBEI MEDICAL UNIVERSITY;1999-03
8 Lei Jianhua;et al(Department of Physiology Hengyang healthy academy,Hengyang,Hunan);Preventive Effect of Gypenoside Against Endotoxic Shock-Induced DIC in rabbit[J];JOURNAL OF HENGYANG MEDICAL COLLEGE;1994-02
9 Jiao Hongli Liu Yilin ★ Wan Laxiang Yang Heping Yang Yongzong(Molecular Biology Center,Hengyang Medical College,Hengyang,421001;Studies on Effect and its Mechanism of L arginine on Porcine Coronary Artery Endothelium[J];BASIC MEDICAL SCIENCES AND CLINICS;1997-04
10 YANG Ai-Lian; TANG Xiao-Qing; WANG XiaoPing; CHEN Yang-Fan; WANG La-Xiang; OU HeSheng; HUANG Zong-Zhi; PENG Jian-Ping; LIU Ge-Xiu; ZHANG Tong and YANG He-Ping(Molecular Biology Center, Hengyang Medical College,Hengyang 421001, China );L-Arginine Improves Endothelium Dependent Vasorelaxation and Reduces the Development of Proliferative atherosclerotic lesions[J];Chinese Journal of Arteriosc Lerosis;1995-01
【Secondary References】
Chinese Journal Full-text Database 10 Hits
1 YU Sheng-zhu, LI Xiao-min, ZHANG Min (Department of Traditional Chinese Medicine,the 324th Hospital,PLA,Chongqing 400020,China);STUDY ON ANTI-LIPOPERIOXIDE AND ENDOTHELIAL CELL PROTECTION EFFECTS OF ZHENGZHI PELLET[J];Journal of Anhui Traditional Chinese Medical College;2002-06
2 ZHANG Jing 1,HUANG Shu-huai 2,ZENG Bai-sheng 2 (1.School of Sports Science,Normal University,Beijing 100875, China;2.College of Physical Education,Yangzhou University,Yangzhou 225002,Jiangsu China);Effect of Mechanism of L-Arg of Aerobic Exercise on Anti-ApoE-Deficient Mice Antherosclerosis[J];Journal of Beijing Sport University;2008-03
3 Zhang Daning et al (Tianjin Academy of Traditional Chinese Medicine);Discuss on The Kidney and “The Heart-The Kidney Axis and The Heart System Theory[J];China Journal of Traditional Chinese Medicine and Pharmacy;2003-10
4 Yang Mei,Xing Lin (Emergency Medicine Department,The Third People's Hospital of Jinan,Jinan 250101,China);Clinical Study of Low-molecular-weight Heparin in Combination With Sodium Ferulate in the Treatment of Acute Cerebral Infarction[J];Chinese Journal of Medicinal Guide;2008-08
5 Liang Mingjin, He Langchong  (College of Pharmacy, Xi′an Jiaotong University, Xi′an 710061);Analysis of the Effective Part and Effective Component of Angelica Sinensis in Siwutang[J];Chinese Journal of Analytical Chemistry;2004-01
6 ZHANG Wei,WANG Chun-hua,LI Feng,WANG Yu-qin,SHEN Yan(Department of Pharmacology,Medical College of Nantong University,Nantong 226001,Jiangsu Province,China);Influence of 2,3,4',5-tetrahydroxystilbene-2-O-β-D glucoside on the expression of matrix metalloproteinases-2,9 in rats with atherosclerosis[J];The Chinese Journal of Clinical Pharmacology;2008-02
7 LONG Wei;JIN Jin;SHEN Xiu;LI Wei-hong;ZHOU Xiao-liang;WANG De-zhi;ZHOU Ze-wei;Institute of Radiation Medicine,Chinese Academy of Medical Sciences & Peking Union Medical College;;Evaluation on Nutritional and Healthy Effects of Northeast Black Soybean by Using Novel System[J];Soybean Science;2014-06
8 Ouyang Jingping, Wang Xiong,Muller S, Department of Pathophysiology,Basic Medical College, Hubei Medical University,Wuhan 430071,China;The Reverse Effect of Angelica on the Reorganization of Cytoskeleton Induced by TNF-α[J];JOURNAL OF HUBEI MEDICAL UNIVERSITY;2000-01
9 BIE Jinghua,OUYANG Jingping,ZHANG Deling Dept.of Pathophysiology,School of Medicine,Wuhan University,Wuhan 430071,China;Role of VASP and PKA in Cell Migration Induced by PDGFBB[J];Medical Journal of Wuhan University;2006-06
10 GAO Shaofang,LI Diangui,JIA Yansu.Hebei Medical University,Hebei,Shijiazhuang 050000;Effect of HXTML on myocardial ischemic rats[J];Hebei Journal of Traditional Chinese Medicine;2008-11
【Secondary Citations】
Chinese Journal Full-text Database 3 Hits
1 YANG Ai-Lian; TANG Xiao-Qing; WANG XiaoPing; CHEN Yang-Fan; WANG La-Xiang; OU HeSheng; HUANG Zong-Zhi; PENG Jian-Ping; LIU Ge-Xiu; ZHANG Tong and YANG He-Ping(Molecular Biology Center, Hengyang Medical College,Hengyang 421001, China );L-Arginine Improves Endothelium Dependent Vasorelaxation and Reduces the Development of Proliferative atherosclerotic lesions[J];Chinese Journal of Arteriosc Lerosis;1995-01
2 YANG He-Ping; YANG Ai-Lian; WANG Xiao-Ping and CHEN Yan-Fang.(Molecular Biology Center, Hengyang Medical College,Hengyang 421001, China);Influence of L-Arginine on the Endothelium Lesion in Atherosclerotic Plaques in Rabbits[J];Chinese Journal of Arteriosc Lerosis;1995-01
3 YANG Yong-Zong; CHEN Yan-Fang; LIU Yi-Lin; LIN Xu-Guang; JIAO Hong-Li; WANG Zhou-Lian; DIN Cui-Fen; WAN La-Xian; YANG He-Ping (Molecular Biology Center, The Second Affiliated Hospital, Hengyang Medical College, Hengyang 421001; Guangdong Institute of Card;Effect of L-arginine on Lipoprotein, Nitric Oxide and Lipid Peroxide in Hypercholesterolaemic Rabbits[J];CHINESE JOURNAL OF ARTERIOSC LEROSIS;1995-03
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