Full-Text Search:
Home|Journal Papers|About CNKI|User Service|FAQ|Contact Us|中文
Add to Favorite Get Latest Update

Apolipoprotein E Polymorphism in 110 Patients with Myocardial Infarction

YANG Zhi-Jian, ZHU Tie-Bing, YANG Bing, JIA Yong-Ping, MA Geng-Shan, KONG Xiang-Qing, CAO Ke-Jiang, ZHANG Fu-Min and MA Wei-Zhu (Department of Cardiology, First Affiliated Hospital, Nanjing Medical University, Naijing 210029, China)  
Aim To study the relation between apolipoprotein E polymorphism and myocardial infarction. Methods 110 patients with myocardial infarction and 131 normals were enrolled and blood samples were collected. Their apoE genotyping were performed by polymerase chain reaction (PCR). Results Both in cases and controls, the allelic frequency of E3/3 was highest, reaching 70.1 percentage of whole volume, hemozygote of apo E3 was moderate, and homozygote E4/4 was lowest. The frequencies of E3/4 and E4/4 was significantly high in patients with myocardial infarction compared with controls (P0.01). It was found primarily that the age of first acute myocardial infarction was earlier in the carriers of E4. Conclusions apo E4 is an important genetic mark of the patients with myocardial infaction. The age of first acute myocardial infarction was earlier in the carriers of E4.
【CateGory Index】: R542.22
Download(CAJ format) Download(PDF format)
CAJViewer7.0 supports all the CNKI file formats; AdobeReader only supports the PDF format.
Chinese Journal Full-text Database 10 Hits
1 CHEN Bao-Sheng;GUO zhong-Min;HE Ping;LU Xin-Yue;BAI Guang-Lin;JIN Ji-Kai;XUE Yan;YE Ping;XUE Hong;WU Gang;CHI Lai-Shun;ZENG Wu-Wei;LU Xiao-Qin and BAI Hai-Hua(Institute of Basic Medical Science,Chinese Academy of Medi cal Sciences and Peking Union Medical;The Distributions and Sequencing of Apo B Gene 3'-Variable Number of Tandemly Repeat Alleles in Chinese Han and Mongolian Nationalities[J];CHINESE JOURNAL OF ARTERIOSC LEROSIS;1996-02
2 XU Kui 1) ,QIU Zhi-ming 2) ,WAN Xiao-ying 2) (1) Department of Pharmacy; 2) Department of Biochemistry, Kunming Medical college, Kunming 650031);The Influence of PCR Amplification with DMSO[J];Academic Journal of Kunming Medical College;2001-01
3 Peng Shu, Peng Jian, Gong Wuxing. The Third Afflicated Hospital of Jinan University, Medical College, Zhuhai Municiple People's Hospital, Zhuhai 519000;Study of correlationship between apolipoprotein E gene polymorphism and coronary heart disease in male and female[J];South China Journal of Cardiovascular Diseases;1999-04
4 The Central Hospital,Qingpu County,Shanghai Yan Xuewei (201700);Observation of Clinical Effect of Notoginseng Total Saponin Tablets in High BloodViscosity and Hyperlipemia[J];SHANGHAI JOURNAL OF TRADITIONAL CHINESE MEDICINE;1999-05
5 Ye Bang ce (Research Institute of Biochemistry,State Key Laboratory of Bioreactor Engineering, East China University of Science & Technology,Shanghai,200237);Pharmacogenomics——Design of Personalized Medicines[J];Progress In Biotechnology;2000-06
6 Luo, Chao-quan Guo, Jun-ruing Yang, Ying-hao Wu, Xin-yao~* Liu, Xi-wen~1 (Department of Biochemistry, Sun Yat-Sen University of Medical Sciences * Department of Forensic Biology, Sun Yat-Sen University of Medical Sciences Guangzhou, 510089);Studying on Genetic Polymorphism of Apoliporotein B Gene 3'-End VNTR in the Han Nationality of Guangdong Province[J];;1993-04
7 LIU Yan-huan,SU Chang-lai(Department of PE,Tianjin Institute of Technology,Tianjin300381,China);Study Progress of ApoE Polymorphism,Exercise,Lipid Metabolism and Coro nary Artery Disease[J];Journal of Tianjin Institute of Physical Education;2003-03
8 Zhao Ruozhi; Liu Ximin; Cai Zhuan et al (Department of Neurology,Tongji Hospital. Tongji Medical University, Wuhan 430030);DNA Polymorphism of the Apolipoprotein B Gene Region in Chinese Population of Wuhan Area[J];ACTAUNIVERSITATIS MEDICTNAE TANGJI;1995-01
9 Gu Yun; Wang Luya; Wu Guixian; et al.(Medical Institute of Beijing Heart Lung and Blood Vessel 100029);The Relation between Apolipoprotein B Gene Loci Polymorphisms and Hyperlipidemia Studied by Polymerase Chain Reaction[J];JOURNAL OF CARDIOVASCULAR AND PULMONARY DISEASES;1998-01
10 ZHANG Li-li, L An-lin, WANG Hai-chang, JIA Guo-liang ( Department of Cardiovasology, Xijing Hospital, Fourth Military Medical University, Xi'an,Shaanxi 710032, China);The relationship between apolipoprotein E polymorphism and risk factors of coronary heart disease[J];Chinese Heart Journal;2004-03
©2006 Tsinghua Tongfang Knowledge Network Technology Co., Ltd.(Beijing)(TTKN) All rights reserved