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《CHINESE JOURNAL OF ARTERIOSC LEROSIS》 1994-04
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Effect of Gypenosides on Nitric Oxide and Lipid Peroxidation in Blood-serum of Diet-induced Atherosclerotic Rabbit

LIAO DuanFang;YIN Wei-Dong;CHEN JianXiong;TEN Hua;TAN Xiao-Qing;LI Bo-Ping and YU Lin (Department of Cardiopulmonary Pharmacology,Institute of Cardiovascular Disease,Hengyang Medical College,Hengyang 421001,China)  
We reported the effects of gypenosides (GPS) on serum levels of nitric oxide(NO),lipid peroxidation(LPO)and superoxide dismudase(SOD)in atherosclerotic rabbit induced by high cholesterol diet.The results showed that GPS 60 mg·d-1 fed in company with 1% cholesterol for 8 weeks and GPS 120 mg·d-1 orally administrated for 4 weeks after development of aortic lesion could significantly protect the activity of NO and SOD,decrease the LPO content as well as lower the serum levels of total cholesterol and triglyceride.
【Fund】: 湖南省教委资助课题
【CateGory Index】: R965
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