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《Chinese Journal of Infection and Chemotherapy》 2002-01
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A study on antimicrobial resistance of clinical isolates of Staphylococcus species

MA Yue, YAO Lei, CHEN Hongbo, et al. National Institute for the Control of Pharmaceutical and Biological Products, National Center for Surveillance of Antimicrobial Resistance, Beijing 100050,China  
Objective: To investigate the antimicrobial resistance of staphylococcal isolates from 51 hospitals in 2000 in China. Methods:Antimicrobial susceptibility test was conducted by disk diffusion technique (K B method). Results:⑴ Resistance rates of MRSA, MRCNS isolates to ciprofloxacin, erythromycin, gentamicin, trimethoprim/sulfamethoxazole, tetracycline , chloramphenicol, and clindamycin were 76.0%, 91.0%, 72.0%, 55.0%, 72.0%, 44.0%, 74.0% and 55.2%, 82.0%, 32.2%, 77.4%, 58.8%, 45.1%, 52.7%, respectively. ⑵ The resistance rates of methicillin sensitive coagulase negative staphylococci (MSCNS) to ciprofloxacin, chloramphenicol, tetracycline and trimethoprim/sulfamethoxazole, were higher than those of methicillin sensitive S aureus (MSSA) MSCNS remains sensitive to most of antimicrobial agents routinely used in clinical practice including ciprofloxacin, gentamicin chloramphenicol and clindamycin, the resistance rates were 24.3%, 7.5%, 31.3%, 24.4%. Conclusions: It is important to monitor the antimicrobial resistance of staphylococcus species.
【CateGory Index】: R446.5
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