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《Chinese Journal of Infection and Chemotherapy》 2005-01
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Surveillance of common pathogenic bacterial resistance in Guangzhou in 2003

YE Hui-fen, CHEN Hui-lin, YANG Yin-mei, LI Hong-yu, SU Dan-hong, Huang Lu-xia.(The First People's Hospital of Guangzhou,Guangzhou510180,China)  
ObjectiveTo investigate the antibiotic resistance of clinical pathogens isolated in Guangzhou.MethodsThe susceptibility of clinical isolates was tested by disk diffusion method.Data were analyzed with WHONET 5.1 software.ResultsA total of 2 047 clinical isolates were analyzed,including 697 strains of gram-positive cocci and 1 350 strains of gram-negative bacilli.Strains of methicillin-resistant Staphylcoccus aureus and methicillin-resistant coagulase-negative Staphylcocci accounted for 70.8% and 82.4% respectively.No vancomycin-resistant Staphylococcus strains was identified.ESBLs-producing strains accounted for 39.2% of E.coli and 44.7% of Klebsiella.The resistance rates of ESBLs-producing strains to antimicrobial agents (except imipenem) were generally higher than those of non-ESBL-producing strains.The resistance rates of Enterobacter sp.to the third generation cephalosporins were relatively higher.ConclusionsIt is important to monitor antimicrobial resistance of clinical pathogens.
【Fund】: 广州市重点攻关项目(2000 Z 027 01 2 2)。
【CateGory Index】: R446.5
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