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《Chinese Journal of Prosthodontics》 2003-01
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Changes in the expression of TrkA mRNA and PPTA mRNA in the dog trigeminal ganglion induced by trauma occlusion

DONG Yan, LIU Hong-chen, WU Sheng-xi, WANG Xin-mu, WEI Jian-hua (Department of stomatology, General hospital of PLA Beijing 100853)  
Objective: To investigate the possible mechanisms of orofacial pain induced by traumatic occlusion, the expression changes of TrkA and PPTA mRNAs were detected in the dog trigeminal ganglion (TG). Method: The occlusal surface of the first and the second maxillary right molars in 10 dogs were unilaterally raised 1.5mm with the casting Ni-Cr high inlay which was fixed in I Class inlay hole . On 3,7,14,30 and 60 days after teeth operation, TG of two sides were removed. The expression of TrkA mRNA and PPTA mRNA in TG were detected in both experimental and control groups with reverse transcription -polymerasa chain reaction (RT_PCR). Results : (1) Both TrkA and PPTA mRNAs expression in the TG of traumatic side were upregulated compared to the contralateral side during observation period (2) The TrkA mRNA expression in the TG of traumatic side was stronger than that in control group at all the time points ,with the higher expression levels during 7-30 days. (3) PPTA mRNA level was increased during 3-30 days and reached the peak level around 3-14 days after traumatic occlusion. No significant change was found between experimental group and control group at 60 days. Conclusion: The present results observed the upregulated expression of TrKA and PPTA mRNAs in dog TG after traumatic occlusion and suggested the possible involvement of TrKA and PPTA in the orofacial pain induced by traumatic occlusion.
【Fund】: 全军医药卫生科研基金(01MB081)
【CateGory Index】: R782
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【References】
Chinese Journal Full-text Database 6 Hits
1 CHEN Jin-wu, LIU Hong-chen, RAO Zhi-ren, ZHANG Han-dong, WANG Qi, WANG Jing-jie.(Department of Stomatology, PLA General Hospital,Beijing,100853,China);The effect of traumatic occlusion on microglias in rat parabrachial nuc1eus and locus coeruleus[J];Chinese Journal of Prosthodontics;2006-02
2 Jia Jing,Liu Hong- chen,Hu ang Zhan,Zhang Han- Dong,Department of Stomatology,General Hospital of Chinese PLA,Beijing 100853,China;Establishment of traumatic occlusion model in rats[J];Chinese Journal of Clinical Rehabilitation;2005-18
3 JIA Jing, LIU Hong-chen, HUANG Zhan, ZHANG Han-Dong.(Department of Stomatology, THE PLA General Hospital ,Beijing. 100853,China);Effects of occlusal trauma on behavior and nutrition of rats[J];Chinese Journal of Geriatric Dentistry;2005-02
4 JIAJing, LIU Hong- chen, ZHANG Han- dong,HUANG Zhan, (Department of Stomatology, The PLAGeneral Hospital , Beijing. 100853,China);Response of astrocytes to occlusal trauma in rat spinal trigeminal nucleus caudalis and its relationship between cytokines[J];Chinese Journal of Geriatric Dentistry;2005-03
5 MA Jun-li, LIU Hong-chen, WANG Guan-chao, E Ling-ling, WANG Dong-sheng, LV-Yan. (Department of stomatology, PLA General Hospital, Beijing, 100853, China);Effects of diet consistency on the expression of Neurotrophin-3(NT-3)/trkc during the development of rat masseter muscle soon after weaning[J];Chinese Journal of Geriatric Dentistry;2007-01
6 DONG Yan *, LIU Hong chen, WANG Xin mu,LIU Da qing,WU Sheng xi. *Department of Stomatology, General Hospital of PLA, Beijing 100853,China;The expression of PPTA and c-fos mRNA in dog caudal spinal trigeminal nucleus induced by traumatic occlusion[J];Chinese Journal of Stomatology;2004-05
【Citations】
Chinese Journal Full-text Database 3 Hits
1 LIU Hong-chen. ( Department of stomatology , General Hospital of PLA. BeiJing 100853);Clinical analysis of early toothache caused by tramatic occlusion[J];Chinese Journal of Prosthodontics;2002-01
2 LIU Hong-Chen. (Department of stomatology, General Hospital of PLA. Beijing 100853);Study of relationship between oral function and brain function[J];Chinese Journal of Prosthodontics;2002-03
3 LIU Hong-chen, TIAN Jia-he, WANG Dong-sheng, CHEN Ying-mao (Department of stomatology , General Hospital ofPLA. BeiJing 100853);Primary study of relationship between the mastication and brain function with PET[J];Chinese Journal of Prosthodontics;2002-04
【Co-citations】
Chinese Journal Full-text Database 10 Hits
1 CHEN Ai-he,GU Yang(Stomatology College of Dalian Medical University,Dalian 116027,China);Dysfunction in chewing system arising from traumatic occlusion and occlusal reconstruction[J];Journal of Dalian Medical University;2006-06
2 SHI Ji-hong,et al(The Fourth Central Hospital of Tianjin,Tianjin 300140,China);Gustatory Acuity and its Improvement in Laryngectomees[J];Hebei Medicine;2007-06
3 YANG Xiu-wen1, LIU Hong-chen1, JIN Zhen2, LI Ke2. (1. Dept. of Stomatology, The PLA Gen- eral Hospital, Beijing 100853, China; 2. Dept. of Radiology, The PLA 306 Hospital, Beijing 100101, China);Cortical activation induced by intraoral stimulation with water in humans with functional magnetic reso-nance imaging[J];West China Journal of Stomatology;2008-04
4 ZHU Mei-ling, LIU Hong-chen, HAO Zuo-qi, DUAN Li-jun.(Department of Stomatology, general hospital of PLA, Beijing100853);Expression of PPTA mRNA in trigeminal ganglion in rat during occlusal trauma[J];Chinese Journal of Prosthodontics;2002-01
5 LIU Hong-Chen. (Department of stomatology, General Hospital of PLA. Beijing 100853);Study of relationship between oral function and brain function[J];Chinese Journal of Prosthodontics;2002-03
6 LIU Hong-chen, TIAN Jia-he, WANG Dong-sheng, CHEN Ying-mao (Department of stomatology , General Hospital ofPLA. BeiJing 100853);Primary study of relationship between the mastication and brain function with PET[J];Chinese Journal of Prosthodontics;2002-04
7 ZHU Mei-ling, LIU Hong-chen, HAO Zuo-qi, DUAN Li-jun (Department of Stomatology, Chinese PLA General Hospital,Beijing 100853 China);Expression of SP, NMDAR_1 in Vc during occlusal trauma in rat[J];Chinese Journal of Prosthodontics;2002-04
8 LIU Hong-chen, CHEN Ying-mao, WANG Dong-sheng, TIAN Jia-he (Department of stomatology , General Hospital of PLA. BeiJing 100853);Primary study of relationship between tast and brain function with PET[J];Chinese Journal of Prosthodontics;2003-01
9 LIU Hong-chen, WANG Dong-sheng, LIU Xiu-fang, ZHANG Qi-xhi.( Department of stomatology , General Hospital ofPLA. BeiJing 100853, China);The study of cerebral blood flow before and after mastication[J];Chinese Journal of Prosthodontics;2003-02
10 ZHANG Qing-shi, LIU Hong-chen, JIN Zhen, LI Ke.( Department of stomatology, General Hospital of PLA. BeiJing100853, China);A study on metabolic changes in cortices caused by mastication using method of magnetic resonance spectroscopy[J];Chinese Journal of Prosthodontics;2004-02
【Co-references】
Chinese Journal Full-text Database 10 Hits
1 ;Optic canal decompression through transcranial approach in treatment of traumatic optic nerve injury[J];Academic Journal of Second Military Medical University;2004-07
2 ZHANG Ying-fan, JIANG Hua *,LIN Zi-hao (Department of Plastic Surgery,Changzheng Hospital,Second Military Medical University,Shanghai 200003,China);Expression regulation of nicotinic acetylcholine receptor subtype and its physiological significance[J];Academic Journal of Second Military Medical University;2005-01
3 GAO Bei, LAN Li, RAO Zhi Ren PLA Institute of Neurosciences, Fourth Military Medical University, Xian 710033, China;Expression changes of Fos protein in neurons and OX42 in microglias of rat MVZ after intraperitoneal lipopolysaccharide injection[J];Journal of The Fourth Military Medical University;2004-08
4 SONG Lian- fang1,MENG Fan tang2,LIU Xi yu 2,et al. (1.Department of Technology,Super People′ s Court of Shandong Province,Jinan,250014; 2.Intermediate People′ s court of rizhao ,Shandong Province,rizhao 276800);A study of the relation between interval of the injury and the reaction of neurons, glial cells after experimental brain contusion[J];Journal of Forersic Medicine;2001-03
5 WANG Yonggang 1, 2) , ZHANG Yong 1) ,ZHANG Qi 1) , WU Aiqun 3) , HE Cheng 1) 1)Department of Neurobiology, the Second Military Medical University, Shanghai 200433 2)Department of Human Anatomy, College of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450052 3)Department of Anatomy, the Second Military Medical University, Shanghai 200433;Expression and distribution of nerve growth factor receptor TrkA in rat spinal cord[J];Journal of Zhengzhou University(Science Medical);2004-03
6 LI Xiao kun 1,HU Ai lian 3,XU Hua 1,ZHENG Yuan yuan 3,YAO Cheng can 1,Hong An 2 1 Biopharmaceutical R&D Center of Jinan University,Guangzhou 510632,China; 2 Institute of Bioengineering of Jinan University,Guangzhou 510632,China; 3 Beijing;PHARMACOLOGIC EFFECT OF RECOMBINANT BOVINE BASIC FIBROBLAST GROWTH FACTOR ON CRUSHED OPTIC NERVE IN RATS[J];West China Journal of Pharmaceutcal Sciences;2001-06
7 Liu Wanying, Zhang Maonian, Chen Bing et al. Department of Neurobiology, Fourth Military Medical Univercity, Xi'an 710032, China;Investigation on flash-visual evoked potentials of SD rats after injuries to optic nerve in different grades[J];Medical Journal of Chinese People's Liberation Army;2004-05
8 HAO Zuo-Qi, LIU Hon g-Chen, ZHU Mei-Ling, DUAN Li-Jun. (PLA Postgraduate Medical School, Beijing 100853);Effect of CGRP immunoreactive nerve fibers in pulpal tissue of traumatic occlusion molar[J];Chinese Journal of Prosthodontics;2001-02
9 DUAN Li-Jun, LIU Hong-Chen, ZHU Mei-Ling, HAO Zuo-Qi, (PLA Postgraduate Medical School, Beijing 100853);The change of CGRP immunoreactive nerve fibers in periodontium by traumatic occlusion[J];Chinese Journal of Prosthodontics;2001-02
10 LIU Hong-chen. ( Department of stomatology , General Hospital of PLA. BeiJing 100853);Clinical analysis of early toothache caused by tramatic occlusion[J];Chinese Journal of Prosthodontics;2002-01
【Secondary References】
Chinese Journal Full-text Database 5 Hits
1 CHEN Jin-wu, LIU Hong-chen, RAO Zhi-ren, ZHANG Han-dong, WANG Qi, WANG Jing-jie.(Department of Stomatology, PLA General Hospital,Beijing,100853,China);The effect of traumatic occlusion on microglias in rat parabrachial nuc1eus and locus coeruleus[J];Chinese Journal of Prosthodontics;2006-02
2 MA Jun-li,LIU Hong-chen,WANG Guan-chao,E Ling-ling,WANG Dong-sheng.(The Stomatological Center,Chinese PLA General Hospital,Beijing 100853,China);Effects of soft-diet feeding on mRNA expression of brain-derived neurotrophic factor/ receptor in rat masseter muscle during postnatal development[J];Stomatology;2009-06
3 Wang Jian-zhong,He Yu-min,Liao Xiao-ping,et al;Analysis of the PGE_2 and TXB_2 in Periodontium of the Rat with Occlusal Trauma[J];Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine;2009-01
4 LI Yan,ZHANG Zhi-guang,WU Shu-yi,LIANG Guo-bin,QIAO Yong-gang,ZHANG Yan-bo.Guanghua School of Stomatology,Inshtitute of Stomatological Research,Sun Yat-sen University,Guangzhou 510055,China;Establishment and evaluation of animal model of increasing occlusal vertical dimension[J];Chinese Journal of Stomatological Research(Electronic Version);2008-05
5 LIU Rui-rui,LIN Xue-feng.Dept.of Prosthodontics,Guanghua School of Stomatology,Sun Yat-sen University,Guangzhou 510055,China;The effect of occlusal interference on stomatognathic system and healthy condition[J];Chinese Journal of Practical Stomatology;2009-04
【Secondary Citations】
Chinese Journal Full-text Database 9 Hits
1 LIU Hong-chen, ZHAO Yan-pin, LI Shi-dong (Dental Department, General Hospital of Chinese PLA Beijing 100853 China);Traumatic occlussion pulpitis caused[J];Chinese Journal of Prosthodontics;2000-01
2 XU Juan, LIU Hong-Chen, WANG Yan-Rong, JIANG Xiang-Hua. (PLA Postgraduate Medical School, Beijing 100853) [;Three-dimensional finite element analysis of the stress of the mandible premolar under loading on its traumatic occlusal spots[J];Chinese Journal of Prosthodontics;2001-01
3 HAO Zuo-Qi, LIU Hon g-Chen, ZHU Mei-Ling, DUAN Li-Jun. (PLA Postgraduate Medical School, Beijing 100853);Effect of CGRP immunoreactive nerve fibers in pulpal tissue of traumatic occlusion molar[J];Chinese Journal of Prosthodontics;2001-02
4 DUAN Li-Jun, LIU Hong-Chen, ZHU Mei-Ling, HAO Zuo-Qi, (PLA Postgraduate Medical School, Beijing 100853);The change of CGRP immunoreactive nerve fibers in periodontium by traumatic occlusion[J];Chinese Journal of Prosthodontics;2001-02
5 ZHU Mei-ling, LIU Hong-chen, HAO Zuo-qi, DUAN Li-jun.(Department of Stomatology, general hospital of PLA, Beijing100853);Expression of PPTA mRNA in trigeminal ganglion in rat during occlusal trauma[J];Chinese Journal of Prosthodontics;2002-01
6 LIU Hong-Chen. (Department of stomatology, General Hospital of PLA. Beijing 100853);Study of relationship between oral function and brain function[J];Chinese Journal of Prosthodontics;2002-03
7 Wang Jiada;et al. (School of stomatologr,Beijing Medical University 100081);Analysis of 28 clinical cases and bone in stress around every tooth with Pericementitis caused by occlusal trauma[J];SHANGHAI JOURNAL OF STOMATOLOGY;1994-01
8 Zhu Meiling, Zhao Min, Hu Sanjue School of Stomatology, The Fourth Military Medical University, Xi'an 710032;Effect of noxious pulpal stimulation on PPTA mRNA -CGRP mRNA in trigiminal ganglion[J];CHINESE JOURNAL OF CONSERVATIVE DENTISTRY;1999-02
9 Shi Yubin,Wang Jiade,Cao Caifang School of Stomatology,Beijing Medical University,Beijing 100081;Clinical studies on pulpitis and periapical periodontitis caused by traumatic occlusion[J];CHINESE JOURNAL OF STOMATOLOGY;1997-01
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